EX-99.1 2 tm2523752d1_ex99-1.htm EXHIBIT 99.1
Exhibit 99.1

| Diagnostics Biotech Company NASDAQ: PRPO Founded in 2011 HQ: New Haven, CT DISCLAIM ER T HIS PRESENT AT ION HAS BEE N PREPARE D B Y P RE CIPIO IN C. (T HE “C O MPAN Y”) AND IS GENERA L BA CKGROUND IN FOR MAT I ON ABOUT T HE C O MPAN Y’S ACT IV IT IES AS O F T HE DAT E O F T HIS PRESENT AT ION . B Y AC CEPT ING T H IS PRESENT AT ION , T HE RE CIPIENT ACKNOW LEDGES AND AG REES T HAT A LL OF T HE IN FOR MAT ION CONT A INED HEREIN IS CO N FIDENT IA L, T HAT T HE RECIP IENT W IL L DIST R IBUT E , D ISC LOSE , AND U SE SUCH IN FOR MAT ION ON L Y FOR SUCH PU RPOSE AND T HAT T HE RECIP IENT SHA L L N OT D IST RIBUT E, D ISC LOSE OR USE SUCH IN FOR MAT IO N IN AN Y W AY DET RI MENT AL T O T HE C O MPAN Y. T HE IN FOR MAT IO N CONT A IN ED HEREIN DOES NOT PURP OR T T O BE A L L INC LUS IVE AN D T HE CO MPAN Y NOR AN Y O F IT S RESPE CT IVE A F FI L IAT ES N OR AN Y O F IT S OR T HE IR CONT RO L L ING PERSONS , O F F ICERS , DIRECT ORS , E MP LO YEES OR REP RESENT AT IVE S MAKES AN Y REP RESENT AT I ON O R W ARRANT Y, E XP RESS OR I MP L IED , AS T O T HE ACCURA C Y, CO MP L ET ENESS OR RE LIAB I LIT Y O F T H E IN FOR MAT ION CONT AI NED I N T HI S PRESENT AT IO N . T H IS PRESENT AT ION D OES NOT CONT A IN A L L T HE IN FOR MAT IO N T HAT IS OR MA Y BE MAT ERIA L T O INVEST O RS OR P OT ENT IA L INVEST OR S AND SHOU LD NOT BE CONS IDERED AS ADVICE OR A RECO MMENDAT ION T O IN VEST ORS OR POT ENT IA L INVEST ORS IN RE SPECT O F T HE HOLD ING , PURCHA SING OR SE L LI NG O F SEC URIT I ES OR OT HER F INANC IA L INST RU MENT S AND DOE S NOT T AKE INT O ACC OUNT AN Y INVEST OR ’S PAR T ICU LAR OBJECT IVES, FINAN CIA L S IT UAT ION OR N EEDS. CERT A IN ST AT E MENT S I N T HIS PRESENT AT I ON MA Y CON ST IT UT E “ FORW ARD-LOOK ING ST AT E MENT S ” W IT HIN T HE MEAN ING O F SECT ION 2 7A O F T HE SECUR IT IES ACT O F 1 93 3 , A S A MEN DED, AND SE CT ION 2 1E O F T HE SE CURIT IE S E XCHAN GE ACT O F 1 9 34 , AS A MEN DED, W HICH I NVOLVE KN OW N AND U NKNOW N RISKS , UNCERT A I NT IES AND OT HER FACT ORS T HAT MA Y CA USE AC T UAL RESU LT S T O B E MAT ER IAL L Y DI F FERENT FR OM A N Y ANT IC IPAT ED / FORECAST E D RESULT S , PER FO R MANCE OR ACH IEVE MENT S E XPRESSED OR I MP L IED B Y SUC H ST AT E MENT S. F ORW ARD-LOOK ING ST AT E MENT S I NC LUDE, BUT ARE NOT LI MIT ED T O, T HOSE W IT H RESPECT T O MANAGE ME NT ’S C URRENT V IEW S AND EST I MA T ES OF FUT URE EC ONO MIC C IRCU MST A NCES, I NDUST R Y COND IT I ONS, CO MPAN Y PERFO R MANCE , F INANC IA L RESU LT S , INC LUD ING T HE ABI L IT Y O F T HE CO MPAN Y T O INCREA SE IT S PRESENCE /I MPA CT / MA RKET SHAR E IN T HE DIA G NOST IC PRODUCT S AND SERVICES MARKET S, AN D REGU LAT OR Y MAT T ERS. T HE SE FORW ARD-LOO KING ST AT E MENT S A RE BASED UPON EST I MAT ES AND ASSU MPT IO NS T HAT , W HILE CONSIDERED REASON ABL E B Y T HE CO MPAN Y AN D IT S MANAGE ME NT , AS T HE CASE MA Y BE , ARE IN HERENT L Y UNCERT A IN . NEW RISKS AND UNCERT AI NT IES MA Y E MER GE FRO M T I ME T O T I ME, AND IT I S NOT POS SIB LE T O PRED ICT AL L RI SKS AND UNC ERT AINT IES. T HE KNOW N RISKS, UNC ERT AINT IES AND OT HER FACT ORS A F FECT IN G T HESE F ORW ARD-LOOK ING ST AT E MENT S A RE DES CRIBED FR O M T I ME T O T I ME IN T HE CO MPAN Y’S F I LI NGS W IT H T HE SECUR IT IES AND E XCHA NGE CO M MISSI ON, INC LUD ING T HE CO MPAN Y’S MOST RE CE NT ANNUA L REPORT ON FO R M 1 0-Q AND 1 0 -K. AN Y CHANGE IN SUCH FACT ORS , R ISKS AND U NCERT A INT IES MA Y CAUSE T HE ACT UA L RESULT S , EVENT S AND PE R FOR MAN CE T O DI F FE R MAT ER IA L L Y FRO M T HOSE RE FERRE D T O IN SUC H ST AT E MENT S. FACT ORS T HAT MA Y C AUSE ACT U AL RESU LT S T O DI F FER MAT ERI AL L Y F RO M CUR R ENT E XPECT AT IONS INC LUDE , BUT ARE NOT LI MIT ED T O , VAR IOUS FACT ORS BE YOND MANAGE ME NT ’ S CO NT RO L IN C LUDIN G GENERA L ECONO MIC COND IT IO NS AND OT HER R ISKS , AS W ELL AS FACT ORS ASSOC IAT ED W IT H CO MPANIE S, SUCH AS PREC IPI O, T HAT ARE EN GAGED IN D IAGNOST ICS AND OT HER RESEARCH AND DEVE L OP MENT ACT IV IT IE S IN T HE B IOT ECHN OL OG Y IN DUST RY, I NC LUDI NG UNCERT A INT Y I N P RODUCT ACCEPT ANCE AND/ OR RECE IPT O F REGULAT OR Y APPROVA LS FOR PRODUCT CAND ID AT ES, INC LUD ING AN Y DE LA YS A ND OT HER I MPA CT S FRO M T HE COV ID 1 9 PANDE MIC . A CCORD ING L Y, T HE CO MPAN Y CLA I MS T HE PROT ECT ION O F T HE SA FE HARBOR FOR FORW ARD-LOOKIN G ST AT EMENT S CO NT AINED IN T HE SEC URIT IES A CT W ITH RESPECT T O A LL ST AT E MENT S CONT AINED IN T HIS PR ESENT AT I ON. A LL IN FOR MA T ION IN T H IS PRESENT AT ION IS AS O F T HE DAT E W HEN T HIS PRESENT AT ION W AS PROVIDED T O T H E RECIP IENT B Y PR ECIP IO AND PREC IPIO DOES N OT UNDERT AKE AN Y DUT Y T O UPDAT E T H IS IN FOR MAT ION , INC LUDI NG AN Y FORW ARD-LO OKING ST A T EMENT S, U NLESS REQU IRED B Y LAW . NO REP RESENT AT I ON OR W ARRANT Y, E XPR ESS OR I MP LIED, IS MA DE AS T O T HE FA IRNESS , ACCURAC Y OR CO MP LET ENESS O F T HE P RESENT AT ION AND T HE IN FOR MAT IO N CONT A INED HERE I N AND NO RE LIA NCE SHOU LD BE P LACE D ON IT . I NFOR MAT I ON IN T H IS PRESENT AT ION ( INC LUDI NG MARK ET DAT A AND ST AT IST ICA L IN FOR MAT ION ) H AS BEEN OBT A INED FRO M VARI O US SOURCES (INC LU DING T H IRD-PART Y S OURCES) AND T HE CO MPA N Y DOE S NOT GUARA NT EE T HE ACCURAC Y OR CO MP LET EN ESS O F SUCH IN F OR MAT ION . W HILE T HE CO MPAN Y BE LIEVE S IT S INT ERNAL RESEARCH IS RE L IAB LE, SUCH RESEARCH HAS N OT BEEN VER I FIED B Y AN Y INDEPENDENT SOURCE. A L L PROJECT IONS, VA LUA T IONS AN D ST AT IST ICA L ANA L YSES A RE PROV IDE D FOR IN FOR MAT ION PURPOS ES ON L Y. T HE CONT ENT S O F T H IS P RESENT AT I ON SHO U LD NOT BE C ONSIDERED T O B E LEGA L , T A X, INVEST MENT OR OT HER ADV ICE, AND AN Y INVEST OR OR PROSPEC T IVE INVEST OR CONS IDER ING T H E PURCHASE O R D ISPOSA L O F AN Y SEC URIT IES O F T HE C O MPAN Y SHOU LD CONS ULT W IT H IT S OW N COUNSE L AND ADVISE RS AS T O A L L LEGA L , T A X, REG UL AT OR Y, F INANCI AL AND RE LAT ED MAT T E RS CONCER NING AN INVEST MENT IN OR DISP OSA L O F SUC H SECU RIT IES AN D AS T O T HEIR SU IT A BIL IT Y FOR SUCH INVEST O R OR PROSPECT IVE I NVEST OR T HIS PRESE NT AT IO N AN D IT S CO NT ENT S ARE CON FI DENT IA L AND PROPR I ET ARY T O T HE CO MPA N Y, AND NO PART O F IT OR IT S SUBJECT MAT T ER MA Y BE REP RODUCED , REDI ST RIBUT ED , PASSE D ON, OR T HE CONT ENT S OT HE RW ISE DIVU LGED , D IRECT L Y OR I NDIRE CT L Y, T O ANY OT HER PERS ON (E XC LUD ING T HE RELEVANT PERSON’S PROFESSIONAL ADVISERS) OR PUBLISHED IN W HOLE OR IN PART FOR ANY PURPOSE W IT HOUT T HE PRIOR W RIT T EN CONSENT OF T HE COMPANY.

| We develop products that save lives 2 Acute Myeloid Leukemia (AML) is one of the deadliest forms of cancer. Physicians treating patients with AML face two unsuitable options. Precipio’s assay enables immediate, targeted treatment - SAVING LIVES Patient diagnosed with AML Molecular tests ordered (10-15 day wait) Consequence: potentially inadequate treatment; targeted therapy options eliminated Begin Standard Chemo; (Don’t wait for molecular results) OPTION 1 Consequence: patient’s life at risk due to treatment delay Wait 10-15 days for Molecular Results OPTION 2 vs 4-hour Rapid AML test All treatment options available DAY 1

| 3 Precipio is eliminating ineffective diagnosis We eliminate both misdiagnosis and diagnostic delays, where outcomes depend on speed and accuracy. of blood cancer diagnoses are incorrect 25-40%* diagnostic errors cost US healthcare annually 10+ $100B** days generally accepted industry turnaround times in molecular testing * Journal of Clinical Oncology: Errors in Cancer Diagnosis. June 2007 American Society of Clinical Oncology: Second-opinion pathologic review, July 2014 ** American Medical Association: Diagnostic error in medicine. Nov 2009

| We’ve built an innovative product development platform, creating an unfair advantage Our Unfair Advantage We are the first customer of every product we develop Our hands-on experience is translated to our customers We develop products in a rapid, cost-effective manner Pathology Service Lab Facilities, equipment & talent Patient samples arriving daily Exceptional clinical team Foundation 4 Diagnostics Product Division R & D Unsolved diagnostic problems drive innovative products Leveraging clinical laboratory to achieve cost-effective, rapid product development

| Our profitable clinical lab business fully funds R&D, significantly de-risking the company ▪ Identifies market needs ▪ Provides infrastructure and patient samples R&D Platform Clinical Lab ▪ Leverages infrastructure & samples for rapid product development Example: Precipio’s BCR-ABL1 assay 1. Most advanced assay in market 2. Development time: 3 months 3. Development cost: <$100K Product Release 5

| 6 We deliver testing options not available before Our products address the key challenges laboratories face: Staff shortage, Capital budgets, and the ability to deliver timely results Factor Competition Precipio Solution Impact Workflow Complex Simple Simplified workflow enables streamlined process, fewer errors, and faster results Labor Skill High Low Lower labor costs; Easier recruiting, training and management of lab staff; Capital Equipment > $1,000,000 < $25,000 Lower economic adoption threshold Gross Margins 10–15% > 50% Attractive, contributing economics Results Delivery 1 – 3 weeks 1 – 3 days Better patient care

| We scale through national distribution partner agreements already in place Go-to-market efficiency through leading channel partners, with nationwide reach 7 POL* Hospital / Academic Reference Lab * Physician-Owned Laboratory

| Blood cancers are just the beginning: Expanding into a $40B+ market * Transparency Market Research Onco-Hematology Molecular Market Testing June 2023 ** BioSpace Molecular Diagnostic Market Size Report Aug 2024 Our technology is platform-ready to expand beyond hematology into broader cancer and molecular testing. 8 10% Other cancers 87% Other Molecular Diagnostics PRESENT: Blood Cancer Genetics TAM: $500M* LONG TERM: Molecular Diagnostics 80% Other Cancers 20% Blood Cancers NEAR TERM: Cancer Genetics TAM $6.7B** TAM $43B** 2025 2027 2030 2.5% blood cancers

| Recurring revenue growth, high-margin outlook 0% 20% 40% 60% 80% 100% Current Short term Long term Revenue mix Products Path services 0% 20% 40% 60% 80% 100% Current Short term Long term Path Services Products Blended Gross Margin Analysis As we scale products and alter the revenue mix, gross margins increase dramatically. 9

| Proven leadership with deep clinical and commercial experience Ilan Danieli CEO Ilan Danieli CEO Dr. Ayman Mohamed CTO Dr. Ayman Mohamed CTO Zaki Sabet COO Zaki Sabet COO Miri Radomski CPO Legal Counsel Miri Radomski CPO & Legal Counsel Stephen Miller CCO Stephen Miller CCO Matt Gage CFO Matt Gage CFO 10

| Precipio: A high-margin, proprietary diagnostics platform with massive upside Disruptive, Proprietary Products Rooted in solutions to real-world diagnostic and monitoring challenges 1 Unique Development Platform - rapid and capital efficient 2 3 Massive Market Opportunity – growing from $0.5B TAM to multi billion-dollar markets in the future 4 Scalable, cost-efficient Go-To-Market with broad coverage distribution model 5 Attractive Business Model – recurring, high margin revenues and a Cash flow positive business 11

| Thank you. Please contact us at investors@precipiodx.com 20250817