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Significant Accounting Policies - Schedule of Property and Equipment Estimated Useful Lives (Detail)
12 Months Ended
Dec. 31, 2015
Laboratory Equipment [Member]  
Property Plant And Equipment [Line Items]  
Property and equipment estimated useful life 5 years
Computer Equipment [Member]  
Property Plant And Equipment [Line Items]  
Property and equipment estimated useful life 3 years
Office Furniture and Equipment [Member]  
Property Plant And Equipment [Line Items]  
Property and equipment estimated useful life 5 years
Leasehold Improvements [Member]  
Property Plant And Equipment [Line Items]  
Property and equipment estimated useful life Lesser of useful life or remaining lease term