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Condensed Consolidated Statements of Cash Flows (unaudited) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Cash flows from operating activities:    
Net loss $ (13,542) $ (8,428)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 741 440
Noncash rent expense 124 (6)
Depreciation and amortization 61 41
Amortization of debt discount and deferred financing costs 127 515
Loss on disposal of property and equipment 4  
Changes in operating assets and liabilities:    
Accounts receivable, prepaid expenses and other current assets (192) (120)
Accounts payable 141 378
Accrued expenses (724) (761)
Net cash used in operating activities (13,260) (7,941)
Cash flows from investing activities:    
Purchases of property and equipment (359) (29)
Decrease in restricted cash 117  
Net cash used in investing activities (242) (29)
Cash flows from financing activities:    
Proceeds from sale of common stock 41 2,411
Proceeds from issuance of loans payable   15,000
Payments on loans payable (1,932) (3,921)
Cash paid for debt issuance costs   (359)
Cash paid for deferred financing costs   (19)
Net cash (used in) provided by financing activities (1,891) 13,112
Net increase in cash and cash equivalents (15,393) 5,142
Cash and cash equivalents — Beginning of period 75,908 51,174
Cash and cash equivalents — End of period 60,515 56,316
Supplemental cash flow information — Interest paid $ 372 $ 163