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Condensed Consolidated Statements of Operations (unaudited) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Income Statement [Abstract]    
Revenue $ 1,192  
Operating expenses:    
Research and development 4,651 $ 9,770
General and administrative 3,587 3,118
Gain on asset sale (1,500)  
Total operating expenses 6,738 12,888
Other income (expense):    
Interest income 33 16
Interest expense (797) (663)
Other expense (29) (7)
Total other expense, net (793) (654)
Net loss attributable to common stockholders $ (6,339) $ (13,542)
Net loss per share attributable to common stockholders:    
Basic and diluted $ (0.22) $ (0.49)
Weighted-average common shares outstanding:    
Basic and diluted 29,019,582 27,362,643