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Stock-Based Compensation - Summary of Stock Option Activity for Amended 2014 Plan and Related Information (Detail)	3 Months Ended
	Mar. 31, 2019 $ / shares shares
Number of shares
Outstanding beginning balance (in shares)	1,635,790
Granted (in shares)	563,000
Exercised (in shares)	0
Canceled/forfeited (in shares)	(8,360)
Expired (in shares)	70
Outstanding ending balance (in shares)	2,190,360
Exercisable (in shares)	650,151
Weighted-Average Exercise Price
Outstanding beginning balance (in usd per share) | $ / shares	$ 11.08
Granted (in usd per share) | $ / shares	0.76
Exercised (in usd per share) | $ / shares	0.00
Canceled/forfeited (in usd per share) | $ / shares	17.81
Expired (in usd per share) | $ / shares	59.48
Outstanding ending balance (in usd per share) | $ / shares	8.40
Exercisable (in usd per share) | $ / shares	$ 25.97
2015 Stock Incentive Plan [Member] | Employee Stock Option [Member]
Number of shares
Outstanding ending balance (in shares)	10,149
Private Dare [Member] | 2015 Stock Incentive Plan [Member] | Employee Stock Option [Member]
Number of shares
Outstanding beginning balance (in shares)	10,149
Outstanding ending balance (in shares)	50,000

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The number of shares into which fully or partially vested stock options outstanding as of the balance sheet date can be currently converted under the option plan.

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The weighted-average price as of the balance sheet date at which grantees can acquire the shares reserved for issuance on vested portions of options outstanding and currently exercisable under the stock option plan.

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Number of options or other stock instruments for which the right to exercise has lapsed under the terms of the plan agreements.

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The number of shares under options that were cancelled during the reporting period as a result of occurrence of a terminating event specified in contractual agreements pertaining to the stock option plan.

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Gross number of share options (or share units) granted during the period.

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Number of options outstanding, including both vested and non-vested options.

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Weighted average price at which option holders acquired shares when converting their stock options into shares.

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Weighted average per share amount at which grantees can acquire shares of common stock by exercise of options.

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