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Grant Awards (Details) - USD ($)
1 Months Ended 3 Months Ended 12 Months Ended
Sep. 30, 2021
Jul. 31, 2021
Aug. 31, 2020
Mar. 31, 2022
Dec. 31, 2018
Dec. 31, 2021
Jun. 30, 2021
Accounts, Notes, Loans and Financing Receivable [Line Items]              
Amount awarded for grant   $ 11,450,000     $ 1,900,000    
Deferred grant funding       $ 9,731,363   $ 10,542,983  
Grant, DARE-FRT1              
Accounts, Notes, Loans and Financing Receivable [Line Items]              
Amount awarded for grant     $ 300,000        
Additional potential grant funding     $ 2,000,000        
Initial payment             $ 48,950,000
Grant, DARE-PTB1              
Accounts, Notes, Loans and Financing Receivable [Line Items]              
Credits recorded to research and development expense for costs related to award       17,000      
Receivable for expenses eligible for reimbursement       19,000      
DARE-LARC1              
Accounts, Notes, Loans and Financing Receivable [Line Items]              
Amount awarded for grant $ 300,000            
Credits recorded to research and development expense for costs related to award       165,000      
Receivable for expenses eligible for reimbursement       173,000      
Business development       $ 5,400,000