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Strategic Agreements (Details) - USD ($)
shares in Thousands
1 Months Ended 3 Months Ended 6 Months Ended
Aug. 31, 2022
Jul. 31, 2022
Mar. 31, 2022
Sep. 30, 2021
Jun. 30, 2021
Jan. 31, 2020
Nov. 30, 2019
May 31, 2018
Apr. 30, 2018
Feb. 28, 2018
Mar. 31, 2017
Jun. 30, 2023
Jun. 30, 2022
Mar. 31, 2022
Jun. 30, 2023
Jun. 30, 2022
Dec. 31, 2021
Dec. 31, 2020
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Total revenue                       $ 0 $ 10,000,000   $ 0 $ 10,000,000    
Upon Achievement of Specified Development and Regulatory Milestones | MilanaPharm                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Milestone payments, contingent amount                           $ 50,000,000        
Microchips Biotech, Inc.                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Payment of additional consideration         $ 1,250,000                          
Common stock issued to microchips capital stock holders (in shares)       700                            
Cash paid to stockholders' representative       $ 75,000                            
Asset acquisition, contingent consideration                                 $ 250,000 $ 500,000
Microchips Biotech, Inc. | Upon Achievement of Specified Development and Regulatory Milestones                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Milestone payments             $ 46,500,000                      
Current portion of contingent consideration             $ 55,000,000                      
ADVA Tec Agreement | Upon Achievement of Specified Development and Regulatory Milestones                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Milestone payments                     $ 14,600,000              
ADVA Tec Agreement | Maximum                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Percentage of royalty rate                     10.00%              
ADVA Tec Agreement | Minimum                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Percentage of royalty rate                     1.00%              
Bayer Healthcare License Agreement                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Upfront license fee paid           $ 1,000,000                        
Milestone payments, contingent amount           310,000,000                        
Total revenue           $ 20,000,000                        
Hennepin License Agreement | Clinical and Regulatory Milestones                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Maximum potential milestone payments $ 6,250,000                                  
Hennepin License Agreement | Sales Milestones                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Maximum potential milestone payments $ 45,000,000                                  
Licensing Agreements | MilanaPharm                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Milestone payments, contingent amount                             1,000,000      
Licensing Agreements | Licensed Product or Process for Vaginal or Urological Use | MilanaPharm                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Milestone payments, contingent amount                           $ 250,000        
Licensing Agreements | Upon Achieving Certain Commercial Milestones | MilanaPharm                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Milestone payments, contingent amount                             850,000      
Licensing Agreements | Maximum | Upon Achieving Certain Development Milestones | MilanaPharm                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Milestone payments, contingent amount     $ 300,000                              
Licensing Agreements | Upon Achievement of Specified Development and Regulatory Milestones | Upon Achieving Certain Commercial Milestones | MilanaPharm                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Milestone payments, contingent amount                     $ 1,200,000              
Licensing Agreements | ADVA Tec Agreement | Upon Reaching Certain Worldwide Net Sales Milestones                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Milestone payments                     $ 20,000,000              
Assignment Agreement | Maximum | Upon Achieving Certain Clinical and Regulatory Development Milestones | Hammock Pharmaceuticals, Inc                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Milestone payments, contingent amount                             1,100,000      
Merger Agreement | Upon Achieving Certain Clinical and Regulatory Development Milestones | Pear Tree Pharmaceuticals, Inc.                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Maximum potential milestone payments               $ 15,500,000                    
Merger Agreement | Upon Achieving Certain Clinical Development, Regulatory And Commercial Milestones | Pear Tree Pharmaceuticals, Inc.                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Milestone payments               3,200,000                    
Pear Tree Pharmaceuticals, Inc. | Sales Milestones                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Maximum potential milestone payments               $ 47,000,000                    
Juniper Pharmaceuticals, Inc                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Upfront license fee paid                 $ 250,000                  
Potential annual license maintenance fee payments, thereafter                 100,000                  
Juniper Pharmaceuticals, Inc | Clinical and Regulatory Milestones                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Maximum potential milestone payments                 13,500,000                  
Juniper Pharmaceuticals, Inc | Sales Milestones                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Maximum potential milestone payments                 $ 30,300,000                  
License and Collaboration Agreement | Strategic Science and Technologies D Limited Liability Company and Strategic Science Technologies Limited Liability Company                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Milestone payments, contingent amount                   $ 18,000,000                
License and Collaboration Agreement | Upon Achieving Certain Commercial Milestones | Strategic Science and Technologies D Limited Liability Company and Strategic Science Technologies Limited Liability Company                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Milestone payments, contingent amount                   $ 100,000,000                
Organon                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Upfront license fee paid   $ 10,000,000                         10,000,000      
First commercial sale amount                             2,500,000      
Milestone payments, contingent amount                             182,500,000      
Sales based milestones amount                       $ 180,000,000     180,000,000      
Catalent and MilanaPharm | Licensing Agreements                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                    
Milestone payments, contingent amount                             $ 1,000,000