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Stock-Based Compensation (Details 1) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 12 Months Ended
Jul. 31, 2015
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
May 31, 2013
Stock-based compensation            
Stock-based compensation   $ 2,662 $ 2,673 $ 5,442    
Stock Options            
Stock-based compensation            
Shares outstanding   308,967 370,547 460,213 446,365  
Weighted average exercise price of options outstanding   $ 60.80 $ 77.23 $ 87.36 $ 114.99  
2013 Plan            
Stock-based compensation            
Shares authorized           500,000
Shares available for grant   100,000        
2013 Plan | Stock Options            
Stock-based compensation            
Shares outstanding   0        
2013 Plan | Stock Options | Minimum            
Stock-based compensation            
Weighted average exercise price of options outstanding   $ 16.70        
2013 Plan | Stock Options | Maximum            
Stock-based compensation            
Weighted average exercise price of options outstanding   $ 88.50        
2013 CEO Plan | Restricted Stock Units            
Stock-based compensation            
Accelerated compensation cost $ 1,200          
2013 CEO Plan | Stock Options            
Stock-based compensation            
Accelerated compensation cost $ 500          
Inducement Awards | Stock Options            
Stock-based compensation            
Shares outstanding   100,000        
Inducement Awards | Stock Options | Minimum            
Stock-based compensation            
Weighted average exercise price of options outstanding   $ 10.00        
Inducement Awards | Stock Options | Maximum            
Stock-based compensation            
Weighted average exercise price of options outstanding   $ 42.60        
2005 Plan            
Stock-based compensation            
Shares available for grant   0        
2005 Plan | Stock Options            
Stock-based compensation            
Shares outstanding   100,000        
2005 Plan | Stock Options | Minimum            
Stock-based compensation            
Weighted average exercise price of options outstanding   $ 60.40        
2005 Plan | Stock Options | Maximum            
Stock-based compensation            
Weighted average exercise price of options outstanding   $ 159.00