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Stockholders' Equity - Additional Information (Details) - USD ($)
$ / shares in Units, $ in Thousands
 3 Months Ended 6 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Jun. 30, 2025
Sep. 30, 2025
Sep. 30, 2024
Dec. 31, 2024
Common Stock, Shares Authorized 400,000,000     400,000,000   400,000,000
Common Stock, Par Value $ 0.0001     $ 0.0001   $ 0.0001
Common Stock, Shares Outstanding 5,907,233     5,907,233   3,420,906
Common Stock, Shares issued 5,907,233     5,907,233   3,420,906
Issuance of preferred shares 10,000,000     10,000,000    
Preferred Stock, Undesignated Shares Authorized 4,818,654     4,818,654   4,818,654
Preferred stock, par value $ 0.0001     $ 0.0001    
Preferred Stock convertible into share of common stock 1     1   1
Weighted average remaining contractual life options exercisable       6 years 3 months 25 days    
Unrecognized Compensation Costs $ 18,400     $ 18,400    
Weighted average remaining vesting period       1 year 6 months 18 days    
Compensation Expense $ 5,500 $ 9   $ 14,000 $ 35  
August 2024 Private Placement Financing [Member] | Pre-Funded Warrants [Member]            
Exercise price $ 0.01     $ 0.01    
Warrant to purchase share of common stock       1,450,661    
Common stock shares       31,882,671    
Warrant purchase       16,666,666    
Offering Price       $ 3    
Common stock warrant       $ 2.99    
Gross proceeds form warrant       $ 99,700    
Agent fees and direct offering expenses       92,300    
fair value allocated       3,200    
Pre-funded warrants       69,400    
Warrant       $ 27,100    
March 2025 Private Placement Financing | Pre-Funded Warrants [Member]            
Exercise price $ 0.01     $ 0.01    
Warrant to purchase share of common stock       378,346    
Common stock shares       3,760,726    
Offering Price       $ 6.04    
Common stock warrant       $ 6.03    
Gross proceeds form warrant       $ 25,000    
Agent fees and direct offering expenses       23,200    
fair value allocated       2,300    
Pre-funded warrants       $ 22,700    
February 2024 Offering 1 [Member]            
Common stock shares       1,178,740    
Warrant purchase       3,200,000    
Offering Price       $ 5.65    
Common stock warrant       $ 5.649    
Gross proceeds form warrant       $ 9,000    
Agent fees and direct offering expenses       8,000    
fair value allocated       900    
Pre-funded warrants       2,400    
Warrant       $ 5,700    
February 2024 Offering 1 [Member] | Pre-Funded Warrants [Member]            
Warrant to purchase share of common stock       421,260    
February 2024 [Member]            
Warrant to purchase share of common stock       3,200,000    
Offering Price       $ 5.65    
Weighted average remaining contractual life options exercisable       5 years    
fair value allocated       $ 5,700    
Risk-free interest rate       4.12%    
Expected dividend yield       0.00%    
Dividend Yield       131.87%    
August 2024 Warrants [Member]            
Issued unregistered warrants to purchase shares of common stock       16,666,666    
Offering Price       $ 4.5    
Weighted average remaining contractual life options exercisable       1 year 9 months 18 days    
fair value allocated       $ 27,100    
Risk-free interest rate       3.83%    
Expected dividend yield       0.00%    
Dividend Yield       177.27%    
2022 Stock Incentive Plan            
Shares remained available for issuance 1,881,121     1,881,121    
Series A Stock Plan            
Issuance of preferred shares 5,181,346     5,181,346    
Prefered Stock ,Shares Outstanding 210     210   210
First Inducement Stock Options            
Number of shares of common stock authorized for issuance       250,000    
Stock Option Award Granted       1,400,000    
Stock Options Description       The option award will vest in four equal annual installments beginning on the first anniversary of the date of issuance, subject to the employee's continued employment with the Company through each applicable vesting date. The option has a 10-year term and an exercise price of $6.45 per share, the January 21, 2025 closing price of the Company’s common stock.    
Risk-free interest rate       4.49%    
Dividend Yield       0.00%    
Volatility Factor Rate       123.41%    
Expected Life       6 years    
Inducement Stock Options [Member]            
Unrecognized Compensation Costs $ 1,400     $ 1,400    
Compensation Expense $ 89 $ 6   $ 326 $ 121  
Inducement Stock Options [Member] | President and Chief Executive Officer [Member]            
Number of shares of common stock authorized for issuance       157    
Stock Option Award Granted     403,000      
Stock Options Description       This award vested as follows: 25% on the one-year anniversary of the Chief Executive Officer's employment start date and an additional 25% on each of the following three anniversaries of the Chief Executive Officer's employment start date, subject to continued employment. The option has a 10-year term and an exercise price of $3,152 per share, the July 6, 2021 closing price of our common stock.    
Risk-free interest rate     1.13%      
Dividend Yield     0.00%      
Volatility Factor Rate     99.36%      
Expected Life     7 years      
Vesting milestone achieved percentage     75.00%      
Inducement Stock Options [Member] | Chief Medical Officer [Member]            
Stock Option Award Granted       157    
Stock Options Description       This employment inducement stock option was awarded in accordance with the employment inducement award exemption provided by Nasdaq Listing Rule 5635(c)(4) and was therefore not awarded under the Company’s stockholder approved equity plan. The option award will vest as follows: 25% upon initiation of a Phase 3 trial; 25% upon database lock; 25% upon acceptance for review of an investigational NDA; and 25% upon approval. The options have a 10-year term and an exercise price of $2,848 per share, the January 15, 2021 closing price of our common stock.    
Estimated Fair Value Of The Inducement Stock Option Award Granted     $ 403      
Risk-free interest rate     11.00%      
Dividend Yield     0.00%      
Volatility Factor Rate     103.94%      
Expected Life     10 years