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Statements of Stockholders' Equity (Unaudited) - USD ($)
$ in Thousands
Common stock
Additional paid-in capital
Accumulated other comprehensive income (loss)
Accumulated deficit
Total
Balance at Beginning of period at Dec. 31, 2021 $ 5 $ 675,346 $ (413) $ (356,281) $ 318,657
Balance at Beginning of period (in shares) at Dec. 31, 2021 54,244,996        
Stockholders' equity          
Exercise of stock options and vesting of restricted stock units   128     128
Exercise of stock options and vesting of restricted stock units (in shares) 146,056        
Issuance of shares in connection with employee stock purchase plan   243     243
Issuance of shares in connection with employee stock purchase plan (in shares) 155,544        
Unrealized gain (loss) on marketable securities     (1,055)   (1,055)
Share-based compensation expense   15,477     15,477
Net loss       (109,054) (109,054)
Balance at end of period at Sep. 30, 2022 $ 5 691,194 (1,468) (465,335) 224,396
Balance at end of period (in shares) at Sep. 30, 2022 54,546,596        
Balance at Beginning of period at Jun. 30, 2022 $ 5 688,253 (1,578) (438,634) 248,046
Balance at Beginning of period (in shares) at Jun. 30, 2022 54,463,235        
Stockholders' equity          
Issuance of shares in connection with employee stock purchase plan   79     79
Issuance of shares in connection with employee stock purchase plan (in shares) 83,361        
Unrealized gain (loss) on marketable securities     110   110
Share-based compensation expense   2,862     2,862
Net loss       (26,701) (26,701)
Balance at end of period at Sep. 30, 2022 $ 5 691,194 (1,468) (465,335) 224,396
Balance at end of period (in shares) at Sep. 30, 2022 54,546,596        
Balance at Beginning of period at Dec. 31, 2022 $ 5 694,733 (966) (492,406) 201,366
Balance at Beginning of period (in shares) at Dec. 31, 2022 54,614,690        
Stockholders' equity          
Exercise of stock options and vesting of restricted stock units (in shares) 98,042        
Issuance of shares in connection with employee stock purchase plan   89     89
Issuance of shares in connection with employee stock purchase plan (in shares) 100,240        
Unrealized gain (loss) on marketable securities     774   774
Share-based compensation expense   9,351     9,351
Net loss       (85,304) (85,304)
Balance at end of period at Sep. 30, 2023 $ 5 704,173 (192) (577,710) 126,276
Balance at end of period (in shares) at Sep. 30, 2023 54,812,972        
Balance at Beginning of period at Jun. 30, 2023 $ 5 701,349 (340) (550,600) 150,414
Balance at Beginning of period (in shares) at Jun. 30, 2023 54,745,680        
Stockholders' equity          
Exercise of stock options and vesting of restricted stock units (in shares) 67,292        
Unrealized gain (loss) on marketable securities     148   148
Share-based compensation expense   2,824     2,824
Net loss       (27,110) (27,110)
Balance at end of period at Sep. 30, 2023 $ 5 $ 704,173 $ (192) $ (577,710) $ 126,276
Balance at end of period (in shares) at Sep. 30, 2023 54,812,972