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Warrants (Details 1) - $ / shares
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Warrants (Equity) [Member]    
Summary of outstanding debt and equity warrants [Line Items]    
Number of Shares, Warrants, Beginning Balance 21,532,062 12,937,902
Number of Shares, Warrants issued to financial advisors   500,000
Number of Shares, Warrants issued with promissory notes   1,785,715
Number of Shares, Warrants issued with term loan 11,764,704 7,424,804
Number of Shares, Warrants expired (292,755) (1,116,359)
Number of Shares, Warrants, Ending Balance 33,004,011 21,532,062
Weighted Average Exercise Price, Beginning Balance $ 0.65 $ 1.88
Weighted Average Exercise Price, Warrants issued to financial advisors   0.28
Weighted Average Exercise Price, Warrants issued with promissory notes   0.28
Weighted Average Exercise Price, Warrants issued with term loan 0.28 0.28
Weighted Average Exercise Price, Warrants expired 46.68 11.52
Weighted Average Exercise Price, Ending Balance $ 0.47 $ 0.65
Weighted Average Remaining Contractual Life, Beginning Period 3 years 9 months 14 days 3 years 10 months 25 days
Weighted Average Remaining Contractual Life, Warrants issued to financial advisors   4 years 5 months 16 days
Weighted Average Remaining Contractual Life, Warrants issued with promissory notes   4 years 4 months 13 days
Weighted Average Remaining Contractual Life, Warrants issued with term loan 4 years 9 months 4 years 8 months 12 days
Weighted Average Remaining Contractual Life, Ending Period 3 years 6 months 18 days 7 months 24 days
Warrants (Liability) [Member]    
Summary of outstanding debt and equity warrants [Line Items]    
Number of Shares, Warrants, Beginning Balance 6,487,500 6,487,500
Number of Shares, Warrants issued to financial advisors  
Number of Shares, Warrants issued with promissory notes  
Number of Shares, Warrants issued with term loan
Number of Shares, Warrants expired
Number of Shares, Warrants, Ending Balance 6,487,500 6,487,500
Weighted Average Exercise Price, Beginning Balance $ 0.35 $ 0.35
Weighted Average Exercise Price, Warrants issued to financial advisors  
Weighted Average Exercise Price, Warrants issued with promissory notes  
Weighted Average Exercise Price, Warrants issued with term loan
Weighted Average Exercise Price, Warrants expired
Weighted Average Exercise Price, Ending Balance $ 0.35 $ 0.35
Weighted Average Remaining Contractual Life, Beginning Period 2 years 7 months 21 days 3 years 7 months 21 days
Weighted Average Remaining Contractual Life, Ending Period 1 year 7 months 21 days 2 years 7 months 21 days