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Intangible Assets (Details Textual) - USD ($) |  | 1 Months Ended | 12 Months Ended |
--- | --- | --- | --- | ---
May 02, 2016 | Jul. 31, 2016 | Dec. 31, 2016 | Dec. 31, 2015 | May 31, 2016
Indefinite-lived Intangible Assets [Line Items] |  |  |  |  |
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Liabilities |  |  |  |  | $ 1,000,000
Stock Issued During Period, Shares, New Issues | 234,297 |  |  |  |
Shares Issued, Price Per Share |  |  | $ 3.00 |  |
Houston Pharmaceuticals, Inc [Member] |  |  |  |  |
Indefinite-lived Intangible Assets [Line Items] |  |  |  |  |
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Liabilities |  |  | $ 3,874,000 |  |
Stock Issued During Period, Shares, New Issues |  | 629,000 |  |  |
Accrued license agreement payment |  | $ 100,000 |  |  |
Share Price |  | $ 6.00 |  |  |
Moleculin LLC [Member] |  |  |  |  |
Indefinite-lived Intangible Assets [Line Items] |  |  |  |  |
Notes Receivable, Related Parties | $ 57,822 |  |  |  |
Royalty On Net Revenues | 2.50% |  |  |  |
Share Price | $ 6.00 |  |  |  |
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Current Liabilities, Notes Payable |  |  | 469,939 |  |
Moleculin LLC [Member] | Acquisition Date One [Member] |  |  |  |  |
Indefinite-lived Intangible Assets [Line Items] |  |  |  |  |
Amortization of Debt Issuance Costs and Discounts |  |  | 145,078 | $ 422,874 |
Moleculin LLC [Member] | License Agreement [Member] | Houston Pharmaceuticals, Inc [Member] |  |  |  |  |
Indefinite-lived Intangible Assets [Line Items] |  |  |  |  |
Stock Issued During Period, Shares, New Issues | 629,000 |  |  |  |
Payments to Acquire Intangible Assets | $ 75,000,000,000 |  |  |  |
Accrued license agreement payment | $ 100,000 |  |  |  |
Shares Issued, Price Per Share | $ 6 |  |  |  |
Moleculin LLC [Member] | Out-Lincense Agreement [Member] | Houston Pharmaceuticals, Inc [Member] |  |  |  |  |
Indefinite-lived Intangible Assets [Line Items] |  |  |  |  |
Licensing Arrangements Consideration Payable | $ 750,000 |  | 750,000 |  |
Licensing Arrangements Reserve |  |  | 1,000,000 |  |
Payments to Acquire Intangible Assets |  |  | $ 1,000,000 |  |
Common Stock [Member] | Moleculin LLC [Member] |  |  |  |  |
Indefinite-lived Intangible Assets [Line Items] |  |  |  |  |
Business Acquisition, Equity Interest Issued or Issuable, Number of Shares | 999,931 |  |  |  |
Business Acquisition, Equity Interest Issued or Issuable, Value Assigned | $ 5,999,586 |  |  |  |

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