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Statements of Stockholders’ Equity (Parenthetical) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2017 | Dec. 31, 2016
Shares issued, price per share (in dollars per share) | $ 1.35 | $ 3.00
Stock issuance costs |  | $ 1,150
Stock issuance costs, sale of units | $ 550 |
Stock warrants exercised, issuance costs | 73 |
Stock issuance costs, stock offering | $ 166 |

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