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Intangible Assets - Narrative (Details) |  | 1 Months Ended | 4 Months Ended | 12 Months Ended
--- | --- | --- | --- | ---
May 02, 2016 USD ($) agreement $ / shares shares | Jul. 31, 2016 USD ($) $ / shares shares | May 02, 2016 USD ($) $ / shares shares | Dec. 31, 2017 USD ($) $ / shares | Dec. 31, 2016 USD ($) $ / shares
Indefinite-lived Intangible Assets [Line Items] |  |  |  |  |
Indemnification period granted to former officers (in years) | 6 years |  |  |  |
Shares of common stock issued | shares |  |  | 234,297 |  |
Shares issued, price per share (in dollars per share) | $ / shares |  |  |  | $ 1.35 | $ 3.00
Licensing agreement term | 3 years |  |  |  |
HPI option termination price | $ 1,000,000 |  | $ 1,000,000 |  |
Houston Pharmaceuticals, Inc |  |  |  |  |
Indefinite-lived Intangible Assets [Line Items] |  |  |  |  |
Price per share of common stock issued (in dollars per share) | $ / shares |  | $ 6.00 |  |  |
Accrued license agreement payment |  | $ 100,000 |  |  |
Shares of common stock issued | shares |  | 629,000 |  |  |
HPI option termination price |  | $ 3,874,000 |  | $ 3,874,000 |
Moleculin LLC |  |  |  |  |
Indefinite-lived Intangible Assets [Line Items] |  |  |  |  |
Price per share of common stock issued (in dollars per share) | $ / shares | $ 6.00 |  | $ 6.00 |  |
Loan to Moleculin | $ 57,822 |  | $ 57,822 |  |
Royalty on net revenues (as a percent) | 2.50% |  | 2.50% |  |
Number of agreements with HPI | agreement | 2 |  |  |  |
Moleculin LLC | Acquisition Date One |  |  |  |  |
Indefinite-lived Intangible Assets [Line Items] |  |  |  |  |
Amortization of debt issuance costs and discounts excluded from pro forma |  |  |  |  | $ 145,078
Moleculin LLC | License Agreement | Houston Pharmaceuticals, Inc |  |  |  |  |
Indefinite-lived Intangible Assets [Line Items] |  |  |  |  |
Accrued license agreement payment | $ 100,000 |  | $ 100,000 |  |
Shares of common stock issued | shares | 629,000 |  |  |  |
Shares issued, price per share (in dollars per share) | $ / shares | $ 6 |  | $ 6 |  |
Payments to acquire intangible assets |  |  |  | 300,000 |
Moleculin LLC | Out-Lincense Agreement | Houston Pharmaceuticals, Inc |  |  |  |  |
Indefinite-lived Intangible Assets [Line Items] |  |  |  |  |
Licensing arrangements consideration payable | $ 750,000 |  | $ 750,000 | 750,000 |
Licensing agreement term | 3 years |  |  |  |
Payments to acquire intangible assets |  |  |  | 1,000,000 |
Licensing arrangements reserve |  |  |  | $ 1,000,000 |
Common Stock | Moleculin LLC |  |  |  |  |
Indefinite-lived Intangible Assets [Line Items] |  |  |  |  |
Business acquisition, equity interest issued (in shares) | shares | 999,931 |  |  |  |
Business acquisition, value of equity interest issued | $ 5,999,586 |  | $ 5,999,586 |  |

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