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Subsequent Events (Details) |  |  |  | 12 Months Ended |
--- | --- | --- | --- | --- | ---
Mar. 22, 2018 USD ($) ft² | Feb. 16, 2018 USD ($) $ / shares shares | Jan. 11, 2018 $ / shares shares | Dec. 31, 2017 $ / shares shares | Dec. 31, 2016 $ / shares shares | May 31, 2016 $ / shares shares
Subsequent Event [Line Items] |  |  |  |  |  |
Number of shares, granted | shares |  |  |  | 835,000 | 460,000 |
Options issued, exercise price (in dollars per share) | $ / shares |  |  |  | $ 2.42 | $ 5.83 |
Warrants to purchase common stock | shares |  |  |  |  |  | 107,802
Warrants, exercise price (in dollars per share) | $ / shares |  |  |  |  |  | $ 7.50
Subsequent Event |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |
Gross proceeds received from sale of shares and warrants | $ |  | $ 9,000,000 |  |  |  |
Exercisable period, subject to beneficial ownership limitations |  | 6 months |  |  |  |
Warrants exercisable period |  | 5 years |  |  |  |
Warrants, exercise price (in dollars per share) | $ / shares |  | $ 2.80 |  |  |  |
Net proceeds from sale of shares and warrants | $ |  | $ 8,270,000 |  |  |  |
Right of first refusal period (in months) |  | 9 months |  |  |  |
Tail fee period (in months) |  | 6 months |  |  |  |
Science Advisory Board Member | Subsequent Event |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |
Number of shares, granted | shares |  |  | 10,000 |  |  |
Options issued, exercise price (in dollars per share) | $ / shares |  |  | $ 1.89 |  |  |
IPX Memorial Drive Investors, LLC | Lease Agreement For Corporate Office Space | Subsequent Event |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |
Rentable square feet | ft² | 2,333 |  |  |  |  |
Lease agreement, initial term | 66 months |  |  |  |  |
Lease agreement, renewal period (in years) | 5 years |  |  |  |  |
Base monthly rent | $ | $ 4,300 |  |  |  |  |
Annual increase in rent expense (as a percent) | 3.00% |  |  |  |  |
Placement Agency Agreement | Subsequent Event |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |
Commission payment to agents (as a percent) |  | 6.50% |  |  |  |
Warrants granted to purchase common stock, percentage |  | 3.00% |  |  |  |
Reimbursement of expenses | $ |  | $ 75,000 |  |  |  |
Common Stock | Subsequent Event |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |
Warrants to purchase common stock | shares |  | 2,145,000 |  |  |  |
Common Stock | Securities Purchase Agreement | Subsequent Event |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |
Shares of common stock sold | shares |  | 4,290,000 |  |  |  |
Price per share of common stock issued (in dollars per share) | $ / shares |  | $ 2.10 |  |  |  |
Employee Stock Option | Science Advisory Board Member | Subsequent Event |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |
Options issued, vesting period (in years) |  |  | 3 years |  |  |

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