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Note 5 - Warrants (Tables) | 12 Months Ended
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Dec. 31, 2022
Notes Tables |
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block] |
|  | Number of Shares Under Outstanding Warrants at December 31, 2022 |  |  | Number of Shares Under Outstanding Warrants at December 31, 2021 |  |  | Weighted Average Exercise Price at December 31, 2022 |  |  | Remaining Contractual Life at December 31, 2022 (Years) |
Liability Classified Warrants (1) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issued February 2017 |  |  | — |  |  |  | 67,349 |  |  | $ | — |  |  |  | — |
Issued February 2018 |  |  | 378,951 |  |  |  | 378,951 |  |  |  | 16.80 |  |  |  | 0.6 |
Issued June 2018 (2) |  |  | 123,836 |  |  |  | 123,836 |  |  |  | 12.20 |  |  |  | 0.9 |
Issued March 2019 |  |  | 263,507 |  |  |  | 263,507 |  |  |  | 6.60 |  |  |  | 1.2 |
Issued April 2019 |  |  | 875,001 |  |  |  | 875,001 |  |  |  | 10.50 |  |  |  | 1.3 |
Issued February 2020 |  |  | 1,015,001 |  |  |  | 1,015,001 |  |  |  | 6.30 |  |  |  | 2.6 |
|  |  | 2,656,296 |  |  |  | 2,723,645 |  |  | $ | 9.49 |  |  |  |  |
Equity Classified Warrants |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issued July 2017 - Consulting (3) |  |  | — |  |  |  | 25,001 |  |  | $ | 15.64 |  |  |  | — |
Issued August 2019 - Consulting |  |  | — |  |  |  | 25,000 |  |  |  | 9.84 |  |  |  | — |
Issued April 2020 - Consulting |  |  | 16,667 |  |  |  | 16,667 |  |  |  | 6.84 |  |  |  | 2.3 |
Issued December 2020 - Consulting |  |  | 8,334 |  |  |  | 8,334 |  |  |  | 4.72 |  |  |  | 3.0 |
Issued April 2021 - Consulting |  |  | 71,500 |  |  |  | 71,500 |  |  |  | 3.63 |  |  |  | 3.3 |
Issued August 2021 - Consulting |  |  | 250,000 |  |  |  | 250,000 |  |  |  | 3.08 |  |  |  | 8.6 |
Issued June 2022 - Consulting |  |  | 50,000 |  |  |  | — |  |  |  | 1.49 |  |  |  | 9.5 |
Issued September 2022 - Consulting |  |  | 250,000 |  |  |  | — |  |  |  | 1.24 |  |  |  | 9.7 |
|  |  | 646,501 |  |  |  | 396,502 |  |  | $ | 2.42 |  |  |  |  |
Balance outstanding |  |  | 3,302,797 |  |  |  | 3,120,147 |  |  | $ | 8.10 |  |  |  |  |
Schedule of Warrants or Rights, Assumptions Used [Table Text Block] |
|  | Year Ended December 31, |
|  | 2022 |  |  | 2021 |
Risk-free interest rate |  |  | 4.2% to 4.8% |  |  |  | 0.1% to 1.1% |
Volatility |  |  | 63.1% to 76.3% |  |  |  | 71.8% to 114.5% |
Expected life (years) |  |  | 0.1 to 2.6 |  |  |  | 0.1 to 3.6 |
Dividend yield |  |  | —% |  |  |  | —% |
Schedule of Warrant Activity [Table Text Block] |
|  | Number of Shares Under Warrant |  |  | Range of Warrant Exercise Price per Share |  |  | Weighted Average Exercise Price |  |  | Weighted Average Remaining Contractual Life (Years) |
Outstanding at December 31, 2021 |  |  | 2,723,645 |  |  | 6.60 to 16.80 |  |  | $ | 9.46 |  |  |  | 2.6 |
Granted |  |  | — |  |  | 6.30 to 6.30 |  |  | $ | — |  |  |  | — |
Exercised |  |  | — |  |  | 6.60 to 6.60 |  |  | $ | 6.60 |  |  |  | — |
Expired |  |  | (67,349 | ) |  | 8.10 to 9.00 |  |  | $ | 8.42 |  |  |  | — |
Outstanding at December 31, 2022 |  |  | 2,656,296 |  |  | 6.30 to 16.80 |  |  | $ | 9.49 |  |  |  | 1.7 |
Vested and Exercisable at December 31, 2022 |  |  | 2,656,296 |  |  | 6.30 to 16.80 |  |  | $ | 9.49 |  |  |  | 1.7 |

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- Definition Tabular disclosure of warrants or rights issued. Warrants and rights outstanding are derivative securities that give the holder the right to purchase securities (usually equity) from the issuer at a specific price within a certain time frame. Warrants are often included in a new debt issue to entice investors by a higher return potential. The main difference between warrants and call options is that warrants are issued and guaranteed by the company, whereas options are exchange instruments and are not issued by the company. Also, the lifetime of a warrant is often measured in years, while the lifetime of a typical option is measured in months. Disclose the title of issue of securities called for by warrants and rights outstanding, the aggregate amount of securities called for by warrants and rights outstanding, the date from which the warrants or rights are exercisable, and the price at which the warrant or right is exercisable. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (a) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5047-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 50 -Section S99 -Paragraph 1 -URI https://asc.fasb.org/extlink&oid=6784392&loc=d3e188667-122775 + Details
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