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Note 6 - Equity (Tables)

12 Months Ended

Dec. 31, 2022

Notes Tables

Share-based Payment Arrangement, Expensed, Amount [Table Text Block]

		Year Ended December 31,
		2022				2021
General and administrative		$	1,467			$	1,461
Research and development			808				912
Total stock-based compensation		$	2,275			$	2,373

Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

		Year Ended December 31,
		2022				2021
Risk-free interest rate			1.6% to 3.3%				0.9% to 1.4%
Volatility			107.0% to 113.2%				114.8% to 118.8%
Expected life (years)			5.3 to 6.3				5.3 to 6.2
Expected dividend yield			—%				—%

Share-Based Payment Arrangement, Option, Activity [Table Text Block]

		Number of Shares				Weighted Average Grant Date Fair Value				Weighted Average Exercise Price				Weighted Average Remaining Contractual Term (years)				Aggregate Intrinsic Value
Outstanding, December 31, 2021			1,438,352			$	6.35			$	8.45				7.8			$	—
Granted			842,832			$	1.26			$	1.49
Exercised			—			$	—			$	—
Forfeited			(5,834	)		$	15.57			$	24.39
Outstanding, December 31, 2022			2,275,350			$	4.44			$	5.83				7.8			$	—
Exercisable, December 31, 2022			927,723			$	7.53			$	10.38				6.3			$	—

Schedule of Nonvested Restricted Stock Units Activity [Table Text Block]

		Number of Shares				Weighted Average Grant Date Fair Value				Weighted Average Remaining Contractual Term (years)
Unvested Shares, December 31, 2021			220,559			$	4.59				3.0
Granted			452,334			$	1.49
Vested			(65,421	)		$	4.98
Unvested Shares, December 31, 2022			607,472			$	2.24				3.1

X

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