<SEC-DOCUMENT>0001140361-21-036646.txt : 20211104
<SEC-HEADER>0001140361-21-036646.hdr.sgml : 20211104
<ACCEPTANCE-DATETIME>20211104213312
ACCESSION NUMBER:		0001140361-21-036646
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20211104
FILED AS OF DATE:		20211104
DATE AS OF CHANGE:		20211104

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Vendola Keith A.
		CENTRAL INDEX KEY:			0001740994

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-41008
		FILM NUMBER:		211382032

	MAIL ADDRESS:	
		STREET 1:		111 LIVORNO WAY
		CITY:			REDWOOD CITY
		STATE:			CA
		ZIP:			94065

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			IO Biotech, Inc.
		CENTRAL INDEX KEY:			0001865494
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				870909276
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		OLE MAALOES VEH 3
		CITY:			COPENHAGEN
		STATE:			G7
		ZIP:			2200
		BUSINESS PHONE:		4570702980

	MAIL ADDRESS:	
		STREET 1:		OLE MAALOES VEH 3
		CITY:			COPENHAGEN
		STATE:			G7
		ZIP:			2200
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>form3.xml
<DESCRIPTION>FORM 3
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<ownershipDocument>

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    <periodOfReport>2021-11-04</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001865494</issuerCik>
        <issuerName>IO Biotech, Inc.</issuerName>
        <issuerTradingSymbol>IOBT</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001740994</rptOwnerCik>
            <rptOwnerName>Vendola Keith A.</rptOwnerName>
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        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O IO BIOTECH, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>OLE MAALOES VEH 3</rptOwnerStreet2>
            <rptOwnerCity>COPENHAGEN</rptOwnerCity>
            <rptOwnerState>G7</rptOwnerState>
            <rptOwnerZipCode>2200</rptOwnerZipCode>
            <rptOwnerStateDescription>DENMARK</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isOfficer>true</isOfficer>
            <officerTitle>Chief Financial Officer</officerTitle>
        </reportingOwnerRelationship>
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    <derivativeTable>
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            <securityTitle>
                <value>Warrants (Right to Buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>12.64</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F2"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>87065</value>
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            <ownershipNature>
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                    <value>134324</value>
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                    <value>D</value>
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    <footnotes>
        <footnote id="F1">These Warrants vest 25% on the one-year anniversary of the October 15, 2021 vesting commencement date, and then in 1/48 monthly increments thereafter, subject to the reporting person's continued service through the applicable vesting date, and subject to 50% acceleration upon a change of control and subject to 100% acceleration upon termination of service by the Issuer without cause or by the reporting person within 24 months of a change of control.</footnote>
        <footnote id="F2">Warrants expire in annual increments on the fifth anniversary of the vesting date.</footnote>
    </footnotes>

    <remarks>Exhibit List: Exhibit 24 - Power of Attorney</remarks>

    <ownerSignature>
        <signatureName>/s/ Brian Burkavage, Attorney-in-Fact for Keith Vendola</signatureName>
        <signatureDate>2021-11-04</signatureDate>
    </ownerSignature>
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<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>vendola.htm
<DESCRIPTION>EXHIBIT 24
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  <div style="text-align: center; font-weight: bold;">POWER OF ATTORNEY</div>
  <div>&#160;</div>
  <div style="text-indent: 36pt;">Know all by these presents, that the undersigned hereby makes, constitutes and appoints each of <u>Mai-Britt Zocca</u> and <u>Brian Burkavage</u>, or either of them acting individually, and with full power of
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        <td style="width: 31.5pt; vertical-align: top; align: right; color: #1F1F1F;">(1)</td>
        <td style="width: auto; vertical-align: top;">
          <div style="color: #1F1F1F;">prepare, execute in the undersigned's name and on the undersigned's behalf, and submit to the U.S. Securities and Exchange Commission (the "SEC") a Form
            ID, including amendments thereto, and any other documents necessary or appropriate to obtain codes and passwords enabling the undersigned to make electronic filings with the SEC of reports required by Section 16(a) of the Securities Exchange
            Act of 1934 or any rule or regulation of the SEC;</div>
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        <td style="width: 31.5pt; vertical-align: top; align: right; color: #1F1F1F;">(2)</td>
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          <div><font style="color: #1F1F1F;">execute for and on behalf of the undersigned, in the undersigned's capacity
              as an officer and/or director of </font>IO Biotech, Inc., <font style="color: #1F1F1F;">a Delaware corporation (the "Company"), Forms 3, 4, and 5, including amendments thereto,
              in accordance with Section 16(a) of the Securities Exchange Act of 1934 and the rules and regulations thereunder;</font></div>
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        <td style="width: 31.5pt; vertical-align: top; align: right;">(3)</td>
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          <div style="color: #1F1F1F;">do and perform any and all acts for and on behalf of the undersigned which may be necessary or desirable to complete and execute any such Form 3, 4, or 5,
            complete and execute any amendment or amendments thereto, and timely file such form with the SEC and any stock exchange or similar authority; and</div>
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        <td style="width: 31.5pt; vertical-align: top; align: right;">(4)</td>
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          <div style="color: #1F1F1F;">take any other action of any type whatsoever in connection with the foregoing which, in the opinion of such attorney-in-fact, may be of benefit to, in the
            best interest of, or legally required by, the undersigned, it being understood that the documents executed by such attorney-in-fact on behalf of the undersigned pursuant to this Power of Attorney shall be in such form and shall contain such
            terms and conditions as such attorney-in-fact may approve in such attorney-in-fact's discretion.</div>
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  <div>&#160;</div>
  <div style="text-indent: 36pt; color: #1F1F1F;">The undersigned hereby grants to each such attorney-in-fact full power and authority to do and perform any and every act and
    thing whatsoever requisite, necessary, or proper to be done in the exercise of any of the rights and powers herein granted, as fully to all intents and purposes as the undersigned might or could do if personally present, with full power of substitution
    or revocation, hereby ratifying and confirming all that such attorney-in-fact, or such attorney-in-fact's substitute or substitutes, shall lawfully do or cause to be done by virtue of this power of attorney and the rights and powers herein granted. The
    undersigned acknowledges that the foregoing attorneys-in-fact, in serving in such capacity at the request of the undersigned, are not assuming, nor is the Company assuming, any of the undersigned's responsibilities to comply with Section 16 of the
    Securities Exchange Act of 1934.</div>
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  <div style="text-indent: 36pt;"><font style="color: #1F1F1F;">This Power of Attorney shall remain in full
      force and effect until the undersigned is no longer required to file Forms 3, 4, and 5 with respect to the undersigned's holdings of and transactions in securities issued by the Company, unless earlier (a) revoked by the undersigned </font><font style="color: #3F3F3F;">i</font><font style="color: #1F1F1F;">n a signed writing delivered to the foregoing
      attorneys-in-fact or (b) superseded by a new power of attorney regarding the purposes outlined herein at a later date.</font></div>
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  <div style="text-indent: 36pt;"><font style="color: #1F1F1F;">IN WITNESS WHEREOF, the undersigned has caused
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          <td style="width: 25%; text-align: center; border-bottom: 2px solid rgb(0, 0, 0);"><font style="font-family: 'Times New Roman',Times,serif; color: rgb(31, 31, 31);">/s/ Keith Vendola</font></td>
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