    <SEC-DOCUMENT>0001493152-22-024146-index.html : 20220826
    <SEC-HEADER>0001493152-22-024146.hdr.sgml : 20220826
    <ACCEPTANCE-DATETIME>20220826144823
    ACCESSION NUMBER:		0001493152-22-024146
    CONFORMED SUBMISSION TYPE:	DEF 14A
    PUBLIC DOCUMENT COUNT:		5
    CONFORMED PERIOD OF REPORT:	20220826
    FILED AS OF DATE:		20220826
    DATE AS OF CHANGE:		20220826

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			LIXTE BIOTECHNOLOGY HOLDINGS, INC.
    		CENTRAL INDEX KEY:			0001335105
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				202903526
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DEF 14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-39717
    		FILM NUMBER:		221204436

    	BUSINESS ADDRESS:
    		STREET 1:		248 ROUTE 25A
    		STREET 2:		NO. 2
    		CITY:			EAST SETAUKET
    		STATE:			NY
    		ZIP:			11733
    		BUSINESS PHONE:		310 203 2902

    	MAIL ADDRESS:
    		STREET 1:		248 ROUTE 25A
    		STREET 2:		NO. 2
    		CITY:			EAST SETAUKET
    		STATE:			NY
    		ZIP:			11733

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	SRKP 7 INC
    		DATE OF NAME CHANGE:	20050803
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DEF 14A
    <SEQUENCE>1
    <FILENAME>formdef14a.htm
    <TEXT>
    Document 1 - file: formdef14a.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>def14a_001.jpg
    <TEXT>
    Document 2 - file: def14a_001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>def14a_002.jpg
    <TEXT>
    Document 3 - file: def14a_002.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>def14a_003.jpg
    <TEXT>
    Document 4 - file: def14a_003.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>def14a_004.jpg
    <TEXT>
    Document 5 - file: def14a_004.jpg

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    </SEC-DOCUMENT>