<SEC-DOCUMENT>0001493152-22-028641.txt : 20221018
<SEC-HEADER>0001493152-22-028641.hdr.sgml : 20221018
<ACCEPTANCE-DATETIME>20221018131420
ACCESSION NUMBER:		0001493152-22-028641
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		15
CONFORMED PERIOD OF REPORT:	20221013
ITEM INFORMATION:		Other Events
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20221018
DATE AS OF CHANGE:		20221018

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			LIXTE BIOTECHNOLOGY HOLDINGS, INC.
		CENTRAL INDEX KEY:			0001335105
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				202903526
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-39717
		FILM NUMBER:		221315536

	BUSINESS ADDRESS:	
		STREET 1:		248 ROUTE 25A
		STREET 2:		NO. 2
		CITY:			EAST SETAUKET
		STATE:			NY
		ZIP:			11733
		BUSINESS PHONE:		310 203 2902

	MAIL ADDRESS:	
		STREET 1:		248 ROUTE 25A
		STREET 2:		NO. 2
		CITY:			EAST SETAUKET
		STATE:			NY
		ZIP:			11733

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	SRKP 7 INC
		DATE OF NAME CHANGE:	20050803
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>form8-k.htm
<TEXT>
<XBRL>
<?xml version="1.0" encoding="utf-8"?>
<html xmlns="http://www.w3.org/1999/xhtml" xmlns:xs="http://www.w3.org/2001/XMLSchema-instance" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:xbrldi="http://xbrl.org/2006/xbrldi" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xmlns:iso4217="http://www.xbrl.org/2003/iso4217" xmlns:ix="http://www.xbrl.org/2013/inlineXBRL" xmlns:ixt="http://www.xbrl.org/inlineXBRL/transformation/2015-02-26" xmlns:ixt-sec="http://www.sec.gov/inlineXBRL/transformation/2015-08-31" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:dei="http://xbrl.sec.gov/dei/2022" xmlns:ref="http://www.xbrl.org/2006/ref" xmlns:us-gaap="http://fasb.org/us-gaap/2022" xmlns:us-gaap-supplement="http://fasb.org/us-gaap-sup/2022q3" xmlns:srt-supplement="http://fasb.org/srt-sup/2022q3" xmlns:us-roles="http://fasb.org/us-roles/2022" xmlns:dtr-types="http://www.xbrl.org/dtr/type/2020-01-21" xmlns:country="http://xbrl.sec.gov/country/2022" xmlns:srt="http://fasb.org/srt/2022" xmlns:LIXT="http://lixte.com/20221013">
<head>
     <title></title>
<meta http-equiv="Content-Type" content="text/html" />
</head>
<!-- Field: Set; Name: xdx; ID: xdx_02B_US%2DGAAP%2D2022 -->
<!-- Field: Set; Name: xdx; ID: xdx_03B_LIXT_lixte.com_20221013 -->
<!-- Field: Set; Name: xdx; ID: xdx_049_20221013_20221013 -->
<!-- Field: Set; Name: xdx; ID: xdx_058_edei%2D%2DEntityCentralIndexKey_0001335105 -->
<!-- Field: Set; Name: xdx; ID: xdx_059_edei%2D%2DAmendmentFlag_false -->
<!-- Field: Set; Name: xdx; ID: xdx_06B_USD_1_iso4217%2D%2DUSD -->
<!-- Field: Set; Name: xdx; ID: xdx_062_Shares_2_xbrli%2D%2Dshares -->
<!-- Field: Set; Name: xdx; ID: xdx_06D_USDPShares_3_iso4217%2D%2DUSD_xbrli%2D%2Dshares -->
<body style="font: 10pt Times New Roman, Times, Serif">
<div style="display: none">
<ix:header>
 <ix:hidden>
  <ix:nonNumeric contextRef="From2022-10-13to2022-10-13" name="dei:EntityCentralIndexKey">0001335105</ix:nonNumeric>
  <ix:nonNumeric contextRef="From2022-10-13to2022-10-13" name="dei:AmendmentFlag">false</ix:nonNumeric>
  </ix:hidden>
 <ix:references>
  <link:schemaRef xlink:href="lixt-20221013.xsd" xlink:type="simple" />
  </ix:references>
 <ix:resources>
    <xbrli:context id="From2022-10-13to2022-10-13">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001335105</xbrli:identifier>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-13</xbrli:startDate>
        <xbrli:endDate>2022-10-13</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-132022-10-13_custom_CommonStockParValue0.0001PerShareMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001335105</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">LIXT:CommonStockParValue0.0001PerShareMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-13</xbrli:startDate>
        <xbrli:endDate>2022-10-13</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-132022-10-13_custom_WarrantsToPurchaseCommonStockParValue0.0001PerShareMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001335105</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">LIXT:WarrantsToPurchaseCommonStockParValue0.0001PerShareMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-13</xbrli:startDate>
        <xbrli:endDate>2022-10-13</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:unit id="USD">
      <xbrli:measure>iso4217:USD</xbrli:measure>
    </xbrli:unit>
    <xbrli:unit id="Shares">
      <xbrli:measure>xbrli:shares</xbrli:measure>
    </xbrli:unit>
    <xbrli:unit id="USDPShares">
      <xbrli:divide>
        <xbrli:unitNumerator>
          <xbrli:measure>iso4217:USD</xbrli:measure>
        </xbrli:unitNumerator>
        <xbrli:unitDenominator>
          <xbrli:measure>xbrli:shares</xbrli:measure>
        </xbrli:unitDenominator>
      </xbrli:divide>
    </xbrli:unit>
  </ix:resources>
 </ix:header>
</div>


<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p>

<!-- Field: Rule-Page --><div style="width: 100%"><div style="border-top: Black 4pt solid; font-size: 1pt; border-bottom: Black 1.5pt solid">&#160;</div></div><!-- Field: /Rule-Page -->

<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 18pt">UNITED
STATES</span></p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 18pt">SECURITIES
AND EXCHANGE COMMISSION</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 12pt"><b>WASHINGTON,
D.C. 20549</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 18pt">FORM
<span id="xdx_901_edei--DocumentType_c20221013__20221013_zmLDwNZgsS36"><ix:nonNumeric contextRef="From2022-10-13to2022-10-13" name="dei:DocumentType">8-K</ix:nonNumeric></span></span></p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">CURRENT
REPORT</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">PURSUANT
TO SECTION 13 OR 15(d) OF THE</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">SECURITIES
EXCHANGE ACT OF 1934</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Date
of Report (Date of earliest event reported): <span id="xdx_905_edei--DocumentPeriodEndDate_c20221013__20221013_zVlLizJ4msYc"><ix:nonNumeric contextRef="From2022-10-13to2022-10-13" format="ixt:datemonthdayyearen" name="dei:DocumentPeriodEndDate">October 13, 2022</ix:nonNumeric></span></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 18pt"><b><span id="xdx_906_edei--EntityRegistrantName_c20221013__20221013_zfJEviTFPEsd"><ix:nonNumeric contextRef="From2022-10-13to2022-10-13" name="dei:EntityRegistrantName">LIXTE
BIOTECHNOLOGY HOLDINGS, INC.</ix:nonNumeric></span></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Exact
name of registrant as specified in its charter)</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="font: 10pt Times New Roman, Times, Serif; width: 32%; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_909_edei--EntityIncorporationStateCountryCode_c20221013__20221013_zgX9mZCEZWb9" style="text-transform: uppercase"><ix:nonNumeric contextRef="From2022-10-13to2022-10-13" format="ixt-sec:stateprovnameen" name="dei:EntityIncorporationStateCountryCode">delaware</ix:nonNumeric></span></span></td>
    <td style="width: 2%">&#160;</td>
    <td style="font: 10pt Times New Roman, Times, Serif; width: 32%; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_902_edei--EntityFileNumber_c20221013__20221013_zphBMhw9q1M4"><ix:nonNumeric contextRef="From2022-10-13to2022-10-13" name="dei:EntityFileNumber">001-39717</ix:nonNumeric></span></span></td>
    <td style="width: 2%">&#160;</td>
    <td style="font: 10pt Times New Roman, Times, Serif; width: 32%; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_904_edei--EntityTaxIdentificationNumber_c20221013__20221013_zpgagvpp0aEj"><ix:nonNumeric contextRef="From2022-10-13to2022-10-13" name="dei:EntityTaxIdentificationNumber">20-2903526</ix:nonNumeric></span></span></td></tr>
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="font: 10pt Times New Roman, Times, Serif; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(State
    or other jurisdiction of incorporation)</span></td>
    <td>&#160;</td>
    <td style="font: 10pt Times New Roman, Times, Serif"><p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Commission</span></p>
    <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">File
    Number)</span></p></td>
    <td>&#160;</td>
    <td style="font: 10pt Times New Roman, Times, Serif"><p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(I.R.S.
    Employer</span></p>
    <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Identification
    Number)</span></p></td></tr>
  </table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_902_edei--EntityAddressAddressLine1_c20221013__20221013_z2g7uaUMvdRl"><ix:nonNumeric contextRef="From2022-10-13to2022-10-13" name="dei:EntityAddressAddressLine1">680
East Colorado Boulevard</ix:nonNumeric></span>, <span id="xdx_90A_edei--EntityAddressAddressLine2_c20221013__20221013_zr1hdmlFaT9k"><ix:nonNumeric contextRef="From2022-10-13to2022-10-13" name="dei:EntityAddressAddressLine2">Suite 180</ix:nonNumeric></span></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90E_edei--EntityAddressCityOrTown_c20221013__20221013_zEb9uQdiyXDk"><ix:nonNumeric contextRef="From2022-10-13to2022-10-13" name="dei:EntityAddressCityOrTown">Pasadena</ix:nonNumeric></span>,
<span id="xdx_90B_edei--EntityAddressStateOrProvince_c20221013__20221013_zCY6B2UTgJq7"><ix:nonNumeric contextRef="From2022-10-13to2022-10-13" format="ixt-sec:stateprovnameen" name="dei:EntityAddressStateOrProvince">California</ix:nonNumeric></span> <span id="xdx_908_edei--EntityAddressPostalZipCode_c20221013__20221013_zhlLNwXQO8Kl"><ix:nonNumeric contextRef="From2022-10-13to2022-10-13" name="dei:EntityAddressPostalZipCode">91101</ix:nonNumeric></span></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Address
of principal executive offices)</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_909_edei--CityAreaCode_c20221013__20221013_zbuhKCmPxbT9"><ix:nonNumeric contextRef="From2022-10-13to2022-10-13" name="dei:CityAreaCode">(631)</ix:nonNumeric></span>
<span id="xdx_90D_edei--LocalPhoneNumber_c20221013__20221013_zCifNxMMoPu3"><ix:nonNumeric contextRef="From2022-10-13to2022-10-13" name="dei:LocalPhoneNumber">830-7092</ix:nonNumeric></span></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Registrant&#8217;s
telephone number, including area code)</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Check
the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under
any of the following provisions (See General Instruction A.2. below):</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="font: 10pt Times New Roman, Times, Serif; width: 0.25in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_909_edei--WrittenCommunications_c20221013__20221013_ze8hKnnLdwib"><ix:nonNumeric contextRef="From2022-10-13to2022-10-13" format="ixt:booleanfalse" name="dei:WrittenCommunications">&#9744;</ix:nonNumeric></span></span></td>
    <td style="font: 10pt Times New Roman, Times, Serif; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Written
    communications pursuant to Rule 425 under the Securities Act of 1933 (17 CFR 230.425)</span></td></tr>
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="font: 10pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="font: 10pt Times New Roman, Times, Serif; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="font: 10pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span><span id="xdx_907_edei--SolicitingMaterial_c20221013__20221013_ziYBNghX4eZk"><ix:nonNumeric contextRef="From2022-10-13to2022-10-13" format="ixt:booleanfalse" name="dei:SolicitingMaterial">&#9744;</ix:nonNumeric></span></td>
    <td style="font: 10pt Times New Roman, Times, Serif; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Soliciting
    material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)</span></td></tr>
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="font: 10pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="font: 10pt Times New Roman, Times, Serif; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="font: 10pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span><span id="xdx_906_edei--PreCommencementTenderOffer_c20221013__20221013_zfxhVBs9JDq1"><ix:nonNumeric contextRef="From2022-10-13to2022-10-13" format="ixt:booleanfalse" name="dei:PreCommencementTenderOffer">&#9744;</ix:nonNumeric></span></td>
    <td style="font: 10pt Times New Roman, Times, Serif; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Pre-commencement
    communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))</span></td></tr>
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="font: 10pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="font: 10pt Times New Roman, Times, Serif; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="font: 10pt Times New Roman, Times, Serif"><span id="xdx_904_edei--PreCommencementIssuerTenderOffer_c20221013__20221013_zs8C13Fdvksg"><ix:nonNumeric contextRef="From2022-10-13to2022-10-13" format="ixt:booleanfalse" name="dei:PreCommencementIssuerTenderOffer">&#9744;</ix:nonNumeric></span></td>
    <td style="font: 10pt Times New Roman, Times, Serif; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Pre-commencement
    communications pursuant to Rule 13e-4(e) under the Exchange Act (17 CFR 240.13e-4(c))</span></td></tr>
  </table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0.25in; text-align: justify; text-indent: -0.25in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0.25in; text-align: justify; text-indent: -0.25in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Securities
registered pursuant to Section 12(b) of the Act:</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0.25in; text-indent: -0.25in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="border-bottom: Black 1.5pt solid; font: 10pt Times New Roman, Times, Serif; width: 42%; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Title
    of Each Class</span></td>
    <td style="padding-bottom: 1.5pt; width: 2%">&#160;</td>
    <td style="border-bottom: Black 1.5pt solid; font: 10pt Times New Roman, Times, Serif; width: 18%; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Trading
    Symbol(s)</span></td>
    <td style="padding-bottom: 1.5pt; width: 2%">&#160;</td>
    <td style="border-bottom: Black 1.5pt solid; font: 10pt Times New Roman, Times, Serif; width: 36%; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Name
    of each exchange on which registered</span></td></tr>
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="font: 10pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90F_edei--Security12bTitle_c20221013__20221013__us-gaap--StatementClassOfStockAxis__custom--CommonStockParValue0.0001PerShareMember_zQw6i68uIB2i"><ix:nonNumeric contextRef="From2022-10-132022-10-13_custom_CommonStockParValue0.0001PerShareMember" name="dei:Security12bTitle">Common
    Stock, par value $0.0001 per share</ix:nonNumeric></span></span></td>
    <td>&#160;</td>
    <td style="font: 10pt Times New Roman, Times, Serif"><p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p>
    <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90D_edei--TradingSymbol_c20221013__20221013__us-gaap--StatementClassOfStockAxis__custom--CommonStockParValue0.0001PerShareMember_zDlyzErPUUVl"><ix:nonNumeric contextRef="From2022-10-132022-10-13_custom_CommonStockParValue0.0001PerShareMember" name="dei:TradingSymbol">LIXT</ix:nonNumeric></span></span></p></td>
    <td>&#160;</td>
    <td style="font: 10pt Times New Roman, Times, Serif"><p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p>
    <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90A_edei--SecurityExchangeName_c20221013__20221013__us-gaap--StatementClassOfStockAxis__custom--CommonStockParValue0.0001PerShareMember_zFrTM0k0Mhz2"><ix:nonNumeric contextRef="From2022-10-132022-10-13_custom_CommonStockParValue0.0001PerShareMember" format="ixt-sec:exchnameen" name="dei:SecurityExchangeName">The
    NASDAQ Stock Market, LLC</ix:nonNumeric></span></span></p></td></tr>
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="font: 10pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_909_edei--Security12bTitle_c20221013__20221013__us-gaap--StatementClassOfStockAxis__custom--WarrantsToPurchaseCommonStockParValue0.0001PerShareMember_zxJWJ4sVPJA9"><ix:nonNumeric contextRef="From2022-10-132022-10-13_custom_WarrantsToPurchaseCommonStockParValue0.0001PerShareMember" name="dei:Security12bTitle">Warrants
    to Purchase Common Stock, par value $0.0001 per share</ix:nonNumeric></span></span></td>
    <td>&#160;</td>
    <td style="font: 10pt Times New Roman, Times, Serif"><p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p>
    <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90D_edei--TradingSymbol_c20221013__20221013__us-gaap--StatementClassOfStockAxis__custom--WarrantsToPurchaseCommonStockParValue0.0001PerShareMember_zXnhlSArmNh8"><ix:nonNumeric contextRef="From2022-10-132022-10-13_custom_WarrantsToPurchaseCommonStockParValue0.0001PerShareMember" name="dei:TradingSymbol">LIXTW</ix:nonNumeric></span></span></p></td>
    <td>&#160;</td>
    <td style="font: 10pt Times New Roman, Times, Serif"><p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p>
    <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90E_edei--SecurityExchangeName_c20221013__20221013__us-gaap--StatementClassOfStockAxis__custom--WarrantsToPurchaseCommonStockParValue0.0001PerShareMember_zllsLzzYqVT2"><ix:nonNumeric contextRef="From2022-10-132022-10-13_custom_WarrantsToPurchaseCommonStockParValue0.0001PerShareMember" format="ixt-sec:exchnameen" name="dei:SecurityExchangeName">The
    NASDAQ Stock Market, LLC</ix:nonNumeric></span></span></p></td></tr>
  </table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; text-indent: 0in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; text-indent: 0in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b></b></span></p>

<!-- Field: Rule-Page --><div style="width: 100%"><div style="border-top: Black 1.5pt solid; font-size: 1pt; border-bottom: Black 4pt solid">&#160;</div></div><!-- Field: /Rule-Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; text-indent: 0in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>


<!-- Field: Page; Sequence: 1 -->
    <div style="border-bottom: Black 1.5pt solid; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="border-collapse: collapse; width: 100%; font-size: 10pt"><tr style="vertical-align: top; text-align: left"><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <div style="break-before: page; margin-top: 6pt"><table cellpadding="0" cellspacing="0" style="border-collapse: collapse; width: 100%; font-size: 10pt"><tr style="vertical-align: top; text-align: left"><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; text-indent: 0in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="font: 10pt Times New Roman, Times, Serif; width: 0.75in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Item
    8.01.</b></span></td>
    <td style="font: 10pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Other
    Events.</b></span></td></tr>
  </table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; text-indent: 0in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; text-indent: 0.5in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">On
October 13, 2022, the Company issued a press release regarding approval of a Phase 1b/2 randomized trial of doxorubicin +/-lb-100 in
advanced soft tissue sarcomas to be conducted by the Spanish Sarcoma Group.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; text-indent: 0.5in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="font: bold 10pt Times New Roman, Times, Serif; width: 0.75in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Item
    9.01.</span></td>
    <td style="font: bold 10pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Financial
    Statements and Exhibits.</span></td></tr>
  </table>
<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 1in; text-align: justify; text-indent: -1in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; text-indent: 0.5in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(d)
There is filed as part of this report the exhibit listed on the accompanying Index to Exhibits, which exhibit is incorporated herein
by reference.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; text-indent: 0.5in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>


<!-- Field: Page; Sequence: 2; Options: NewSection; Value: 2 -->
    <div style="border-bottom: Black 1.5pt solid; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="border-collapse: collapse; width: 100%; font-size: 10pt"><tr style="vertical-align: top; text-align: left"><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->2<!-- Field: /Sequence --></td></tr></table></div>
    <div style="break-before: page; margin-top: 6pt"><table cellpadding="0" cellspacing="0" style="border-collapse: collapse; width: 100%; font-size: 10pt"><tr style="vertical-align: top; text-align: left"><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">SIGNATURES</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; text-indent: 0.5in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Pursuant
to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by
the undersigned hereunto duly authorized.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; text-indent: 0.5in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="font: 10pt Times New Roman, Times, Serif; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Date:
    October 18, 2022</span></td>
    <td colspan="2" style="font: 10pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">LIXTE
    BIOTECHNOLOGY HOLDINGS, INC. </span></td></tr>
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="font: 10pt Times New Roman, Times, Serif; width: 50%; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="font: 10pt Times New Roman, Times, Serif; width: 3%; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="font: 10pt Times New Roman, Times, Serif; width: 47%; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="font: 10pt Times New Roman, Times, Serif; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="font: 10pt Times New Roman, Times, Serif; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">By:
    </span></td>
    <td style="border-bottom: Black 1.5pt solid; font: 10pt Times New Roman, Times, Serif; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>/s/
    JOHN S. KOVACH</i></span></td></tr>
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="font: 10pt Times New Roman, Times, Serif; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="font: 10pt Times New Roman, Times, Serif; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="font: 10pt Times New Roman, Times, Serif; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">John
    S. Kovach, Chief Executive Officer</span></td></tr>
  </table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>


<!-- Field: Page; Sequence: 3; Value: 2 -->
    <div style="border-bottom: Black 1.5pt solid; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="border-collapse: collapse; width: 100%; font-size: 10pt"><tr style="vertical-align: top; text-align: left"><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->3<!-- Field: /Sequence --></td></tr></table></div>
    <div style="break-before: page; margin-top: 6pt"><table cellpadding="0" cellspacing="0" style="border-collapse: collapse; width: 100%; font-size: 10pt"><tr style="vertical-align: top; text-align: left"><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>INDEX
TO EXHIBITS</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="border-bottom: Black 1.5pt solid; font: 10pt Times New Roman, Times, Serif; width: 0.75in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Exhibit
    No.</b></span></td>
    <td style="width: 0.1in">&#160;</td>
    <td style="border-bottom: Black 1.5pt solid; font: 10pt Times New Roman, Times, Serif; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Description</b></span></td></tr>
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="font: 10pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td>&#160;</td>
    <td style="font: 10pt Times New Roman, Times, Serif; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="font: 10pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">99.1</span></td>
    <td>&#160;</td>
    <td style="font: 10pt Times New Roman, Times, Serif; text-align: justify"><a href="ex99-1.htm"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Press Release regarding approval of a Phase 1b/2 randomized trial of doxorubicin +/-lb-100 in advanced soft tissue sarcomas to be conducted by the Spanish Sarcoma Group</span></a></td></tr>
  <tr style="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <td style="font: 10pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; background-color: white">104</span></td>
    <td>&#160;</td>
    <td style="font: 10pt Times New Roman, Times, Serif; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; background-color: white">Cover
    Page Interactive Data File (embedded within the Inline XBRL document)</span></td></tr>
  </table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-indent: 0.5in"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>


<!-- Field: Page; Sequence: 4; Options: Last -->
    <div style="border-bottom: Black 1.5pt solid; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="border-collapse: collapse; width: 100%; font-size: 10pt"><tr style="vertical-align: top; text-align: left"><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->4<!-- Field: /Sequence --></td></tr></table></div>
    <!-- Field: /Page -->
</body>
</html>
<!-- Field: Set; Name: xdx; ID: xdx_08B_extensions -->
<!-- eJydkMFOwzAMhp9g72BVHKctqTSEehsVTIgNVds0uJrWY9HauHLSwR6JtyRNmbhwgShSZNn/9/9OkoyTBd+bmgRebtdL2FLT1ugJ1rQnIVtSmMgfHjMI75rejPOC1sfyIsw5aChoZhN9jaERR0/GUZWBVlN9M01T0DrTM5ivklHfz9nuTUXWG6wBbQWFcCuGPMp5IGzxgy0352i1I3GGbcBN1ND+hFTpFJ74hO8sRwfLZZ6MxvGMkoVw1/Y2nfPcwF1NTfByg/TnxihlnMmeUfrN3JaLTsoDOgp7NWw3nstjgbLDuiM1UUrpgmRzQKEVNa8kAaFVGtLMv6NdSOAZLiwYYBBpY2hR4NQD4WpAQhs+0vXQX6L9N8ifPb8Avb+d/A== -->
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>2
<FILENAME>ex99-1.htm
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center; background-color: white"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>&nbsp;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: right; background-color: white"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Exhibit
99.1</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center; background-color: white"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>&nbsp;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; background-color: white"><IMG SRC="ex99-1_001.jpg" ALT="" STYLE="height: 97px; width: 220px"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; background-color: white"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>LIXTE
BIOTECHNOLOGY ANNOUNCES APPROVAL OF A PHASE 1B/2 RANDOMIZED TRIAL OF DOXORUBICIN +/-LB-100 IN ADVANCED SOFT TISSUE SARCOMAS TO BE CONDUCTED
BY THE SPANISH SARCOMA GROUP</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>&nbsp;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">PASADENA,
CA, October 13, 2022 &mdash; <U>LIXTE Biotechnology Holdings, Inc. (Nasdaq: LIXT),</U> (&ldquo;LIXTE&rdquo; or the &ldquo;Company&rdquo;),
a clinical-stage pharmaceutical company focused on developing and commercializing cancer therapies, announced that the Spanish Agency
for Medicines and Health Products (Agencia Espa&ntilde;ola de Medicamentos y Productos Sanitarios, AEMPS) has authorized a Phase 1b/randomized
Phase 2 study of LB-100, the Company&rsquo;s lead clinical compound, plus doxorubicin versus doxorubicin alone, the global standard for
initial treatment of advanced soft tissue sarcomas (ASTS).</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Dr.
John Kovach, the founder and CEO of LIXTE, said, &ldquo;The purpose of this clinical trial is to obtain information with respect to the
efficacy and safety of LB-100 combined with doxorubicin in soft tissue sarcomas. Doxorubicin alone has been the cornerstone of first
line treatment of ASTS for over 40 years, with little therapeutic gain from adding cytotoxic compounds to or substituting other cytotoxic
compounds for doxorubicin. In animal models, LB-100 has consistently enhanced the anti-tumor activity of doxorubicin without apparent
increases in toxicity. The interim analysis of this clinical trial will be done before full accrual is completed to determine whether
the study has the possibility of showing superiority of the combination of LB-100 plus doxorubicin compared to doxorubicin alone. A positive
study would have the potential to change the standard therapy for this disease after four decades of failure to improve the marginal
benefit of doxorubicin alone.&rdquo;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Dr.
Kovach continued, &ldquo;This study was designed and will be carried out by the <U>Spanish Sarcoma Group (Grupo Espa&ntilde;ol de Investigaci&oacute;n
en Sarcomas, or GEIS</U>). GEIS was formed in 1994 by oncologists from four hospitals and has grown to include members from more than
60 medical centers across Spain. For relatively uncommon but life-threatening diseases like ASTS, GEIS has shown that it is essential
for many institutions to collaborate and accrue a large enough group of patients needed to timely evaluate promising new treatments.
We are delighted that GEIS has chosen to study whether LIXTE&rsquo;s lead clinical compound, LB-100, can significantly improve the anti-tumor
activity of doxorubicin, the current clinical standard, an only marginally effective treatment for previously untreated ASTS. The clinical
trial is expected to begin later this year or during the first quarter of 2023; up to 170 patients will be entered onto the trial, which
is expected to be completed within two and a half years. This rapid rate of patient accrual is only possible through the collaborative
efforts of GEIS oncologists.&rdquo;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Dr.
Javier Mart&iacute;n-Broto, Coordinating Investigator of the trial, medical oncologist at the <FONT STYLE="background-color: white">Fundaci&oacute;n
Jim&eacute;nez D&iacute;az University Hospital (Madrid) and GEIS Co-Founder</FONT>, commented, &ldquo;Although there has been an increase
in overall survival in advanced sarcoma in recent years, this gain has not been accompanied by advances in first line therapy. Anthracyclines,
and specifically doxorubicin, is still the standard initial treatment. The growing list of negative phase III trials indicates to us
that sarcoma therapy is in crisis. It is true that sarcoma encompasses more than 60 different subtypes and, for some of them, substantial
advances have emerged. But it is also true that the most frequent sarcoma subtypes desperately need a turning point. One promising topic
of research is the combination of doxorubicin with drugs that are able to impair the mechanisms of DNA repair. LB-100 has demonstrated
synergistic action in in vivo preclinical mesenchymal tumors. GEIS will lead a European initiative to conduct a Phase 1/randomized II
trial exploring the combination of doxorubicin plus LB-100 in first line of advanced soft tissue sarcomas.&rdquo;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>


<!-- Field: Page; Sequence: 5 -->
    <DIV STYLE="margin-bottom: 6pt; border-bottom: Black 1.5pt solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%; font-size: 10pt"><TR STYLE="vertical-align: top; text-align: left"><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%; font-size: 10pt"><TR STYLE="vertical-align: top; text-align: left"><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Dr.
Kovach added, &ldquo;We believe that authorization of this trial by AEMPS should facilitate approval of other LB-100 protocols in EU
countries.&rdquo;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; background-color: #FCFCFC"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>About
LIXTE Biotechnology Holdings, Inc.</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><U>LIXTE
Biotechnology Holdings, Inc. (Nasdaq: LIXT)</U>, is a clinical-stage pharmaceutical company focused on new targets for cancer drug development
and developing and commercializing cancer therapies. Major drivers of cancer are defects in the switches that turn the biochemical pathways
in cells on or off. Most cancer research over the past 30 years has focused on the &ldquo;on&rdquo; switches because the &ldquo;off&rdquo;
switches, especially the master &ldquo;off&rdquo; switch protein phosphatase (PP2A), were believed to cause intolerable toxicity in patients.
LIXTE has achieved a breakthrough with its novel, first-in-class lead clinical compound and PP2A inhibitor, LB-100, demonstrating that
LB-100 is readily tolerated in cancer patients at doses associated with anti-cancer activity. Based on extensive published preclinical
data (see <U>www.lixte.com</U>), LB-100 has the potential to significantly improve outcomes for patients undergoing various chemotherapies
or immunotherapies. LIXTE&rsquo;s new approach has no known competitors and is covered by a comprehensive patent portfolio. Initial proof-of-concept
clinical trials are in progress.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; background-color: #FCFCFC"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; background-color: #FCFCFC"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Forward-Looking
Statements</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; background-color: #FCFCFC"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; background-color: #FCFCFC"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">This
announcement contains certain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, and Section
21E of the Securities Exchange Act of 1934. For example, statements regarding the Company&rsquo;s financial position, business strategy
and other plans and objectives for future operations, and assumptions and predictions about future activities, including the continuing
development of proprietary compounds, the planning, funding, coordination and potential results of clinical trials, and the patent and
legal costs to protect and maintain the Company&rsquo;s intellectual property worldwide, are all forward-looking statements. These statements
are generally accompanied by words such as &ldquo;intend,&rdquo; anticipate,&rdquo; &ldquo;believe,&rdquo; &ldquo;estimate,&rdquo; &ldquo;potential(ly),&rdquo;
&ldquo;continue,&rdquo; &ldquo;forecast,&rdquo; &ldquo;predict,&rdquo; &ldquo;plan,&rdquo; &ldquo;may,&rdquo; &ldquo;will,&rdquo; &ldquo;could,&rdquo;
&ldquo;would,&rdquo; &ldquo;should,&rdquo; &ldquo;expect&rdquo; or the negative of such terms or other comparable terminology. The Company
believes that the assumptions and expectations reflected in such forward-looking statements are reasonable, based on information available
to it on the date hereof, but the Company cannot provide assurances that these assumptions and expectations will prove to have been correct
or that the Company will take any action that the Company may presently be planning. However, these forward-looking statements are inherently
subject to known and unknown risks and uncertainties. Actual results or experience may differ materially from those expected or anticipated
in the forward-looking statements. Factors that could cause or contribute to such differences include, but are not limited to, regulatory
policies, available cash, research results, competition from other similar businesses, and market and general economic factors. This
discussion should be read in conjunction with the Company&rsquo;s filings with the United States Securities and Exchange Commission at
<U>http://www.sec.gov/edgar.shtml</U>.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; background-color: #FCFCFC"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; background-color: #FCFCFC"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Lixte
Contact:</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify; background-color: #FCFCFC"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><U>info@lixte.com</U></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">General
Phone: (631) 830-7092</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Investor
Phone: (888) 289-5533</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>


<!-- Field: Page; Sequence: 6; Options: Last -->
    <DIV STYLE="margin-bottom: 6pt; border-bottom: Black 1.5pt solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%; font-size: 10pt"><TR STYLE="vertical-align: top; text-align: left"><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>ex99-1_001.jpg
<TEXT>
begin 644 ex99-1_001.jpg
M_]C_X  02D9)1@ ! 0$ 8 !@  #_VP!#  @&!@<&!0@'!P<)"0@*#!0-# L+
M#!D2$P\4'1H?'AT:'!P@)"XG("(L(QP<*#<I+# Q-#0T'R<Y/3@R/"XS-#+_
MVP!# 0D)"0P+#!@-#1@R(1PA,C(R,C(R,C(R,C(R,C(R,C(R,C(R,C(R,C(R
M,C(R,C(R,C(R,C(R,C(R,C(R,C(R,C+_P  1" "W : # 2(  A$! Q$!_\0
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MDWO]Z+_OH_X4>3>_WHO^^C_A0!=HJEY-[_>B_P"^C_A1Y-[_ 'HO^^C_ (4
M7:*I>3>_WHO^^C_A1Y-[_>B_[Z/^% %VBJ7DWO\ >B_[Z/\ A1Y-[_>B_P"^
MC_A0!=HJEY-[_>B_[Z/^%'DWO]Z+_OH_X4 7:*I>3>_WHO\ OH_X4>3>_P!Z
M+_OH_P"% %VBJ7DWO]Z+_OH_X4>3>_WHO^^C_A0!=HJEY-[_ 'HO^^C_ (4>
M3>_WHO\ OH_X4 7:*I>3>_WHO^^C_A1Y-[_>B_[Z/^% %VBJ7DWO]Z+_ +Z/
M^%'DWO\ >B_[Z/\ A0!=HJEY-[_>B_[Z/^%'DWO]Z+_OH_X4 7:*I>3>_P!Z
M+_OH_P"%'DWO]Z+_ +Z/^% %VBJ7DWO]Z+_OH_X4>3>_WHO^^C_A0!=HJEY-
M[_>B_P"^C_A1Y-[_ 'HO^^C_ (4 7:*I>3>_WHO^^C_A1Y-[_>B_[Z/^% %V
MBJ7DWO\ >B_[Z/\ A1Y-[_>B_P"^C_A0!=HJEY-[_>B_[Z/^%'DWO]Z+_OH_
MX4 7:*I>3>_WHO\ OH_X4>3>_P!Z+_OH_P"% %VBJ0AO/[T7_?1_PI3]KC/*
M!QCJI_QH N454CO 6VL"K#J",&K2L&'% "T444 %(QVC-+5.]F*)@9)/  [T
M ->22XE\J+_@3=@*Y?Q/X[TOPG(;.WB-]J1&60, (^GWV[>N .W.,@TGCKQ,
M_A30H[>T93J=YD*V?]6,?,_X< ?7/."*\1 9V9Y&+.QRS,<DGU->C@\'[7WY
M['GXS&>R]R&YT6J>/_%&K,V[46M(B01%9CR@N!CAA\WOR36=_P )%XA_Z#VJ
M?^!DG^-4:*]>-"G%644>1*O4D[N3+W_"1>(?^@]JG_@9)_C1_P )%XA_Z#VJ
M?^!DG^-4:*KV-/LON0O:S[O[V7O^$B\0_P#0>U3_ ,#)/\:/^$B\0_\ 0>U3
M_P #)/\ &J-%'L:?9?<@]K/N_O9>_P"$B\0_]![5/_ R3_&C_A(O$/\ T'M4
M_P# R3_&J-%'L:?9?<@]K/N_O9>_X2+Q#_T'M4_\#)/\:/\ A(O$/_0>U3_P
M,D_QJC11[&GV7W(/:S[O[V7O^$B\0_\ 0>U3_P #)/\ &C_A(O$/_0>U3_P,
MD_QJC11[&GV7W(/:S[O[V7O^$B\0_P#0>U3_ ,#)/\:/^$B\0_\ 0>U3_P #
M)/\ &J-%'L:?9?<@]K/N_O9>_P"$B\0_]![5/_ R3_&C_A(O$/\ T'M4_P#
MR3_&J-%'L:?9?<@]K/N_O9>_X2+Q#_T'M4_\#)/\:/\ A(O$/_0>U3_P,D_Q
MJC11[&GV7W(/:S[O[V7O^$B\0_\ 0>U3_P #)/\ &C_A(O$/_0>U3_P,D_QJ
MC11[&GV7W(/:S[O[V7O^$B\0_P#0>U3_ ,#)/\:/^$B\0_\ 0>U3_P #)/\
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MW6O^O^?_ -&-6?7U5+X%Z+\CY:K\;]7^85=T1(Y?$NCPRHLD4E]"CHXRK*7
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M8KZR/PH^4E\3"BBBJ$%%%% '0> ?^2AZ1]9?_1+U] CI7S]X!_Y*'I'UE_\
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M2U[R"OG8RY9*78^AE'FBX]SYS32=4V#_ (E=]_X#O_A3O[*U/_H&7W_@._\
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M$NUW^[:_]\-_\51_PEVN_P!VU_[X;_XJLRBCZC0_E#Z[7_F-/_A+M=_NVO\
MWPW_ ,51_P )=KO]VU_[X;_XJLRBCZC0_E#Z[7_F-/\ X2[7/[MK_P!\-_\
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M'<GU-5:*J.#HQ?,EJ*6+K27*V%%%%=)S!4<OW:DJ.7[M)[#6Y]*ZC_Q]6O\
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M5^=0:=N5OGTY>9R;]W?F:U.GFP=3$U)SMRN6FZ]WK:W7:R9F:?I4]_J@L?\
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M0?V;2[L\>_X5YXM_Z!!_\"(O_BJ/^%>>+?\ H$'_ ,"(O_BJ]A_XFW_/V?\
MOVO^%'_$V_Y^S_W[7_"C^TZW9!_9M+NSQ[_A7GBW_H$'_P "(O\ XJC_ (5Y
MXM_Z!!_\"(O_ (JO8?\ B;?\_9_[]K_A1_Q-O^?L_P#?M?\ "C^TZW9!_9M+
MNSQ[_A7GBW_H$'_P(B_^*H_X5YXM_P"@0?\ P(B_^*KV'_B;?\_9_P"_:_X4
M?\3;_G[/_?M?\*/[3K=D']FTN[/'O^%>>+?^@0?_  (B_P#BJ/\ A7GBW_H$
M'_P(B_\ BJ]A_P")M_S]G_OVO^%'_$V_Y^S_ -^U_P */[3K=D']FTN[/'O^
M%>>+?^@0?_ B+_XJC_A7GBW_ *!!_P# B+_XJO8?^)M_S]G_ +]K_A1_Q-O^
M?L_]^U_PH_M.MV0?V;2[L\>_X5YXM_Z!!_\  B+_ .*H_P"%>>+?^@0?_ B+
M_P"*KV'_ (FW_/V?^_:_X4?\3;_G[/\ W[7_  H_M.MV0?V;2[L\>_X5YXM_
MZ!!_\"(O_BJ/^%>>+?\ H$'_ ,"(O_BJ]A_XFW_/V?\ OVO^%'_$V_Y^S_W[
M7_"C^TZW9!_9M+NSQ[_A7GBW_H$'_P "(O\ XJC_ (5YXM_Z!!_\"(O_ (JO
M8?\ B;?\_9_[]K_A1_Q-O^?L_P#?M?\ "C^TZW9!_9M+NSQ[_A7GBW_H$'_P
M(B_^*H_X5YXM_P"@0?\ P(B_^*KV'_B;?\_9_P"_:_X4?\3;_G[/_?M?\*/[
M3K=D']FTN[/'O^%>>+?^@0?_  (B_P#BJ/\ A7GBW_H$'_P(B_\ BJ]A_P")
MM_S]G_OVO^%'_$V_Y^S_ -^U_P */[3K=D']FTN[/'O^%>>+?^@0?_ B+_XJ
MC_A7GBW_ *!!_P# B+_XJO8?^)M_S]G_ +]K_A1_Q-O^?L_]^U_PH_M.MV0?
MV;2[L\>_X5YXM_Z!!_\  B+_ .*H_P"%>>+?^@0?_ B+_P"*KV'_ (FW_/V?
M^_:_X4?\3;_G[/\ W[7_  H_M.MV0?V;2[L\>_X5YXM_Z!!_\"(O_BJ/^%>>
M+?\ H$'_ ,"(O_BJ]A_XFW_/V?\ OVO^%'_$V_Y^S_W[7_"C^TZW9!_9M+NS
MQ[_A7GBW_H$'_P "(O\ XJC_ (5YXM_Z!!_\"(O_ (JO8?\ B;?\_9_[]K_A
M1_Q-O^?L_P#?M?\ "C^TZW9!_9M+NSQ[_A7GBW_H$'_P(B_^*H_X5YXM_P"@
M0?\ P(B_^*KV'_B;?\_9_P"_:_X4?\3;_G[/_?M?\*/[3K=D']FTN[/'O^%>
M>+?^@0?_  (B_P#BJ/\ A7GBW_H$'_P(B_\ BJ]A_P")M_S]G_OVO^%'_$V_
MY^S_ -^U_P */[3K=D']FTN[/'O^%=^+?^@0?_ B+_XJK=C\+_$UW*5N88+)
M!C+RS*V1WP$SS]<5ZL/[5_Y^S_W[7_"GFWOI\>;=28']T[?Y8I/,JS70:RZB
MGU,+0?!^B>$9!.[M?ZF!@.RCY?\ =7HO'<DGK@\XK>CBFO;CSY^,?<0=%'^>
M]36VF1PXPHJ^D84<"N*=251\TG=G9"G&"Y8JR"- BX%/HHJ"PHHHH **** #
M I-H]*** #:/2C:/2BB@ VCTHVCTHHH -H]*-H]*** #:/2C:/2BB@ VCTHV
MCTHHH -H]*-H]*** #:/2C:/2BB@ VCTHVCTHHH -H]*-H]*** #:/2C:/2B
MB@ VCTHVCTHHH -H]*-H]*** #:/2C:/2BB@ VCTHVCTHHH -H]*-H]*** #
M:/2C:/2BB@ VCTHVCTHHH -H]*-H]*** #:/2C:/2BB@ VCTHVCTHHH -H]*
/,"BB@!:*** "BBB@#__9

end
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-101.SCH
<SEQUENCE>4
<FILENAME>lixt-20221013.xsd
<DESCRIPTION>INLINE XBRL TAXONOMY EXTENSION SCHEMA DOCUMENT
<TEXT>
<XBRL>
<?xml version="1.0" encoding="US-ASCII" ?>
    <!-- Field: Doc-Info; Name: Generator; Value: GoFiler Complete; Version: 5.16a -->
    <!-- Field: Doc-Info; Name: VendorURI; Value: https://www.novaworks.com -->
    <!-- Field: Doc-Info; Name: Status; Value: 0x00000000 -->
    <!-- Field: Doc-Info; Name: Misc; Value: 96Mps7xRiXgen8uDanwsWaqOubP9z5Z8yekhvWB9bVka/yosmmFnpSDSA9PmUYQE -->
<schema xmlns="http://www.w3.org/2001/XMLSchema" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xmlns:xbrldi="http://xbrl.org/2006/xbrldi" xmlns:dei="http://xbrl.sec.gov/dei/2022" xmlns:us-gaap="http://fasb.org/srt-sup/2022q3" xmlns:srt="http://fasb.org/srt/2022" xmlns:srt-types="http://fasb.org/srt-types/2022" xmlns:dtr-types="http://www.xbrl.org/dtr/type/2020-01-21" xmlns:LIXT="http://lixte.com/20221013" elementFormDefault="qualified" targetNamespace="http://lixte.com/20221013">
    <annotation>
      <appinfo>
	<link:roleType roleURI="http://lixte.com/role/Cover" id="Cover">
	  <link:definition>00000001 - Document - Cover</link:definition>
	  <link:usedOn>link:presentationLink</link:usedOn>
	  <link:usedOn>link:calculationLink</link:usedOn>
	  <link:usedOn>link:definitionLink</link:usedOn>
	</link:roleType>
	<link:linkbaseRef xlink:type="simple" xlink:href="lixt-20221013_pre.xml" xlink:role="http://www.xbrl.org/2003/role/presentationLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:title="Presentation Links" />
	<link:linkbaseRef xlink:type="simple" xlink:href="lixt-20221013_lab.xml" xlink:role="http://www.xbrl.org/2003/role/labelLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:title="Label Links" />
	<link:linkbaseRef xlink:type="simple" xlink:href="lixt-20221013_def.xml" xlink:role="http://www.xbrl.org/2003/role/definitionLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:title="Definition Links" />
      </appinfo>
    </annotation>
    <import namespace="http://www.xbrl.org/2003/instance" schemaLocation="http://www.xbrl.org/2003/xbrl-instance-2003-12-31.xsd" />
    <import namespace="http://www.xbrl.org/2003/linkbase" schemaLocation="http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd" />
    <import namespace="http://xbrl.sec.gov/dei/2022" schemaLocation="https://xbrl.sec.gov/dei/2022/dei-2022.xsd" />
    <import namespace="http://fasb.org/us-gaap/2022" schemaLocation="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd" />
    <import namespace="http://fasb.org/us-gaap-sup/2022q3" schemaLocation="https://xbrl.fasb.org/us-gaap/2022q3/us-gaap-sup-2022q3.xsd" />
    <import namespace="http://fasb.org/srt-sup/2022q3" schemaLocation="https://xbrl.fasb.org/srt/2022q3/srt-sup-2022q3.xsd" />
    <import namespace="http://fasb.org/us-types/2022" schemaLocation="https://xbrl.fasb.org/us-gaap/2022/elts/us-types-2022.xsd" />
    <import namespace="http://www.xbrl.org/dtr/type/2020-01-21" schemaLocation="https://www.xbrl.org/dtr/type/2020-01-21/types.xsd" />
    <import namespace="http://xbrl.sec.gov/country/2022" schemaLocation="https://xbrl.sec.gov/country/2022/country-2022.xsd" />
    <import namespace="http://fasb.org/srt/2022" schemaLocation="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd" />
    <import namespace="http://fasb.org/srt-types/2022" schemaLocation="https://xbrl.fasb.org/srt/2022/elts/srt-types-2022.xsd" />
    <element id="LIXT_CommonStockParValue0.0001PerShareMember" name="CommonStockParValue0.0001PerShareMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="LIXT_WarrantsToPurchaseCommonStockParValue0.0001PerShareMember" name="WarrantsToPurchaseCommonStockParValue0.0001PerShareMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
</schema>
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-101.DEF
<SEQUENCE>5
<FILENAME>lixt-20221013_def.xml
<DESCRIPTION>INLINE XBRL TAXONOMY EXTENSION DEFINITION LINKBASE DOCUMENT
<TEXT>
<XBRL>
<?xml version="1.0" encoding="US-ASCII" standalone="no"?>
    <!-- Field: Doc-Info; Name: Generator; Value: GoFiler Complete; Version: 5.16a -->
    <!-- Field: Doc-Info; Name: VendorURI; Value: https://www.novaworks.com -->
    <!-- Field: Doc-Info; Name: Status; Value: 0x00000000 -->
<link:linkbase xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xmlns:xbrli="http://www.xbrl.org/2003/instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
    <link:roleRef roleURI="http://lixte.com/role/Cover" xlink:href="lixt-20221013.xsd#Cover" xlink:type="simple" />
    <link:arcroleRef xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#hypercube-dimension" arcroleURI="http://xbrl.org/int/dim/arcrole/hypercube-dimension" />
    <link:arcroleRef xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-domain" arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-domain" />
    <link:arcroleRef xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#domain-member" arcroleURI="http://xbrl.org/int/dim/arcrole/domain-member" />
    <link:arcroleRef xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#all" arcroleURI="http://xbrl.org/int/dim/arcrole/all" />
    <link:arcroleRef xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#notAll" arcroleURI="http://xbrl.org/int/dim/arcrole/notAll" />
    <link:arcroleRef xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-default" arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-default" />
    <link:definitionLink xlink:type="extended" xlink:role="http://lixte.com/role/Cover" xlink:title="00000001 - Document - Cover">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaapStatementLineItems" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaapStatementTable" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xbrldt:contextElement="segment" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapStatementTable" xlink:type="arc" order="10" xbrldt:closed="true" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementClassOfStockAxis" xlink:label="loc_us-gaapStatementClassOfStockAxis" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaapStatementTable" xlink:to="loc_us-gaapStatementClassOfStockAxis" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfStockDomain" xlink:label="loc_us-gaapClassOfStockDomain" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaapStatementClassOfStockAxis" xlink:to="loc_us-gaapClassOfStockDomain" xlink:type="arc" order="20" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfStockDomain" xlink:label="loc_us-gaapClassOfStockDomain_10" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_us-gaapStatementClassOfStockAxis" xlink:to="loc_us-gaapClassOfStockDomain_10" xlink:type="arc" order="30" />
      <link:loc xlink:type="locator" xlink:href="lixt-20221013.xsd#LIXT_CommonStockParValue0.0001PerShareMember" xlink:label="loc_LIXTCommonStockParValue0.0001PerShareMember_10" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapClassOfStockDomain" xlink:to="loc_LIXTCommonStockParValue0.0001PerShareMember_10" xlink:type="arc" order="11" />
      <link:loc xlink:type="locator" xlink:href="lixt-20221013.xsd#LIXT_WarrantsToPurchaseCommonStockParValue0.0001PerShareMember" xlink:label="loc_LIXTWarrantsToPurchaseCommonStockParValue0.0001PerShareMember_20" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapClassOfStockDomain" xlink:to="loc_LIXTWarrantsToPurchaseCommonStockParValue0.0001PerShareMember_20" xlink:type="arc" order="21" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentType" xlink:label="loc_deiDocumentType_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentType_40" xlink:type="arc" order="0" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_AmendmentFlag" xlink:label="loc_deiAmendmentFlag_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiAmendmentFlag_40" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_AmendmentDescription" xlink:label="loc_deiAmendmentDescription_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiAmendmentDescription_40" xlink:type="arc" order="2" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentRegistrationStatement" xlink:label="loc_deiDocumentRegistrationStatement_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentRegistrationStatement_40" xlink:type="arc" order="3" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentAnnualReport" xlink:label="loc_deiDocumentAnnualReport_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentAnnualReport_40" xlink:type="arc" order="4" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentQuarterlyReport" xlink:label="loc_deiDocumentQuarterlyReport_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentQuarterlyReport_40" xlink:type="arc" order="5" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentTransitionReport" xlink:label="loc_deiDocumentTransitionReport_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentTransitionReport_40" xlink:type="arc" order="6" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentShellCompanyReport" xlink:label="loc_deiDocumentShellCompanyReport_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentShellCompanyReport_40" xlink:type="arc" order="7" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentShellCompanyEventDate" xlink:label="loc_deiDocumentShellCompanyEventDate_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentShellCompanyEventDate_40" xlink:type="arc" order="8" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentPeriodStartDate" xlink:label="loc_deiDocumentPeriodStartDate_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentPeriodStartDate_40" xlink:type="arc" order="9" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentPeriodEndDate" xlink:label="loc_deiDocumentPeriodEndDate_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentPeriodEndDate_40" xlink:type="arc" order="10" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentFiscalPeriodFocus" xlink:label="loc_deiDocumentFiscalPeriodFocus_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentFiscalPeriodFocus_40" xlink:type="arc" order="11" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentFiscalYearFocus" xlink:label="loc_deiDocumentFiscalYearFocus_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentFiscalYearFocus_40" xlink:type="arc" order="12" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CurrentFiscalYearEndDate" xlink:label="loc_deiCurrentFiscalYearEndDate_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiCurrentFiscalYearEndDate_40" xlink:type="arc" order="13" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityFileNumber" xlink:label="loc_deiEntityFileNumber_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityFileNumber_40" xlink:type="arc" order="14" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityRegistrantName" xlink:label="loc_deiEntityRegistrantName_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityRegistrantName_40" xlink:type="arc" order="15" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityCentralIndexKey" xlink:label="loc_deiEntityCentralIndexKey_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityCentralIndexKey_40" xlink:type="arc" order="16" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityPrimarySicNumber" xlink:label="loc_deiEntityPrimarySicNumber_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityPrimarySicNumber_40" xlink:type="arc" order="17" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityTaxIdentificationNumber" xlink:label="loc_deiEntityTaxIdentificationNumber_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityTaxIdentificationNumber_40" xlink:type="arc" order="18" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityIncorporationStateCountryCode" xlink:label="loc_deiEntityIncorporationStateCountryCode_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityIncorporationStateCountryCode_40" xlink:type="arc" order="19" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressAddressLine1" xlink:label="loc_deiEntityAddressAddressLine1_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityAddressAddressLine1_40" xlink:type="arc" order="20" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressAddressLine2" xlink:label="loc_deiEntityAddressAddressLine2_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityAddressAddressLine2_40" xlink:type="arc" order="21" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressAddressLine3" xlink:label="loc_deiEntityAddressAddressLine3_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityAddressAddressLine3_40" xlink:type="arc" order="22" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressCityOrTown" xlink:label="loc_deiEntityAddressCityOrTown_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityAddressCityOrTown_40" xlink:type="arc" order="23" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressStateOrProvince" xlink:label="loc_deiEntityAddressStateOrProvince_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityAddressStateOrProvince_40" xlink:type="arc" order="24" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressCountry" xlink:label="loc_deiEntityAddressCountry_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityAddressCountry_40" xlink:type="arc" order="25" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressPostalZipCode" xlink:label="loc_deiEntityAddressPostalZipCode_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityAddressPostalZipCode_40" xlink:type="arc" order="26" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CountryRegion" xlink:label="loc_deiCountryRegion_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiCountryRegion_40" xlink:type="arc" order="27" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CityAreaCode" xlink:label="loc_deiCityAreaCode_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiCityAreaCode_40" xlink:type="arc" order="28" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_LocalPhoneNumber" xlink:label="loc_deiLocalPhoneNumber_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiLocalPhoneNumber_40" xlink:type="arc" order="29" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_Extension" xlink:label="loc_deiExtension_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiExtension_40" xlink:type="arc" order="30" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_WrittenCommunications" xlink:label="loc_deiWrittenCommunications_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiWrittenCommunications_40" xlink:type="arc" order="31" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_SolicitingMaterial" xlink:label="loc_deiSolicitingMaterial_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiSolicitingMaterial_40" xlink:type="arc" order="32" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_PreCommencementTenderOffer" xlink:label="loc_deiPreCommencementTenderOffer_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiPreCommencementTenderOffer_40" xlink:type="arc" order="33" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_PreCommencementIssuerTenderOffer" xlink:label="loc_deiPreCommencementIssuerTenderOffer_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiPreCommencementIssuerTenderOffer_40" xlink:type="arc" order="34" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_Security12bTitle" xlink:label="loc_deiSecurity12bTitle_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiSecurity12bTitle_40" xlink:type="arc" order="35" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_NoTradingSymbolFlag" xlink:label="loc_deiNoTradingSymbolFlag_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiNoTradingSymbolFlag_40" xlink:type="arc" order="36" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_TradingSymbol" xlink:label="loc_deiTradingSymbol_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiTradingSymbol_40" xlink:type="arc" order="37" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_SecurityExchangeName" xlink:label="loc_deiSecurityExchangeName_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiSecurityExchangeName_40" xlink:type="arc" order="38" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_Security12gTitle" xlink:label="loc_deiSecurity12gTitle_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiSecurity12gTitle_40" xlink:type="arc" order="39" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_SecurityReportingObligation" xlink:label="loc_deiSecurityReportingObligation_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiSecurityReportingObligation_40" xlink:type="arc" order="40" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_AnnualInformationForm" xlink:label="loc_deiAnnualInformationForm_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiAnnualInformationForm_40" xlink:type="arc" order="41" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_AuditedAnnualFinancialStatements" xlink:label="loc_deiAuditedAnnualFinancialStatements_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiAuditedAnnualFinancialStatements_40" xlink:type="arc" order="42" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityWellKnownSeasonedIssuer" xlink:label="loc_deiEntityWellKnownSeasonedIssuer_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityWellKnownSeasonedIssuer_40" xlink:type="arc" order="43" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityVoluntaryFilers" xlink:label="loc_deiEntityVoluntaryFilers_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityVoluntaryFilers_40" xlink:type="arc" order="44" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityCurrentReportingStatus" xlink:label="loc_deiEntityCurrentReportingStatus_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityCurrentReportingStatus_40" xlink:type="arc" order="45" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityInteractiveDataCurrent" xlink:label="loc_deiEntityInteractiveDataCurrent_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityInteractiveDataCurrent_40" xlink:type="arc" order="46" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityFilerCategory" xlink:label="loc_deiEntityFilerCategory_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityFilerCategory_40" xlink:type="arc" order="47" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntitySmallBusiness" xlink:label="loc_deiEntitySmallBusiness_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntitySmallBusiness_40" xlink:type="arc" order="48" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityEmergingGrowthCompany" xlink:label="loc_deiEntityEmergingGrowthCompany_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityEmergingGrowthCompany_40" xlink:type="arc" order="49" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityExTransitionPeriod" xlink:label="loc_deiEntityExTransitionPeriod_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityExTransitionPeriod_40" xlink:type="arc" order="50" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentAccountingStandard" xlink:label="loc_deiDocumentAccountingStandard_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentAccountingStandard_40" xlink:type="arc" order="51" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_OtherReportingStandardItemNumber" xlink:label="loc_deiOtherReportingStandardItemNumber_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiOtherReportingStandardItemNumber_40" xlink:type="arc" order="52" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityShellCompany" xlink:label="loc_deiEntityShellCompany_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityShellCompany_40" xlink:type="arc" order="53" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityPublicFloat" xlink:label="loc_deiEntityPublicFloat_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityPublicFloat_40" xlink:type="arc" order="54" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityBankruptcyProceedingsReportingCurrent" xlink:label="loc_deiEntityBankruptcyProceedingsReportingCurrent_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityBankruptcyProceedingsReportingCurrent_40" xlink:type="arc" order="55" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityCommonStockSharesOutstanding" xlink:label="loc_deiEntityCommonStockSharesOutstanding_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityCommonStockSharesOutstanding_40" xlink:type="arc" order="56" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentsIncorporatedByReferenceTextBlock" xlink:label="loc_deiDocumentsIncorporatedByReferenceTextBlock_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentsIncorporatedByReferenceTextBlock_40" xlink:type="arc" order="57" />
    </link:definitionLink>
</link:linkbase>
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-101.LAB
<SEQUENCE>6
<FILENAME>lixt-20221013_lab.xml
<DESCRIPTION>INLINE XBRL TAXONOMY EXTENSION LABEL LINKBASE DOCUMENT
<TEXT>
<XBRL>
<?xml version="1.0" encoding="US-ASCII" standalone="no"?>
    <!-- Field: Doc-Info; Name: Generator; Value: GoFiler Complete; Version: 5.16a -->
    <!-- Field: Doc-Info; Name: VendorURI; Value: https://www.novaworks.com -->
    <!-- Field: Doc-Info; Name: Status; Value: 0x00000000 -->
<link:linkbase xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xbrli="http://www.xbrl.org/2003/instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
    <link:roleRef xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedLabel" roleURI="http://www.xbrl.org/2009/role/negatedLabel" />
    <link:roleRef xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodEndLabel" roleURI="http://www.xbrl.org/2009/role/negatedPeriodEndLabel" />
    <link:roleRef xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodStartLabel" roleURI="http://www.xbrl.org/2009/role/negatedPeriodStartLabel" />
    <link:roleRef xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTotalLabel" roleURI="http://www.xbrl.org/2009/role/negatedTotalLabel" />
    <link:roleRef xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedNetLabel" roleURI="http://www.xbrl.org/2009/role/negatedNetLabel" />
    <link:roleRef xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTerseLabel" roleURI="http://www.xbrl.org/2009/role/negatedTerseLabel" />
    <link:roleRef xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/net-2009-12-16.xsd#netLabel" roleURI="http://www.xbrl.org/2009/role/netLabel" />
    <link:labelLink xlink:type="extended" xlink:role="http://www.xbrl.org/2003/role/link">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementClassOfStockAxis" xlink:label="us-gaap_StatementClassOfStockAxis" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StatementClassOfStockAxis" xlink:to="us-gaap_StatementClassOfStockAxis_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StatementClassOfStockAxis_lbl" xml:lang="en-US">Class of Stock [Axis]</link:label>
      <link:loc xlink:type="locator" xlink:href="lixt-20221013.xsd#LIXT_CommonStockParValue0.0001PerShareMember" xlink:label="LIXT_CommonStockParValue0.0001PerShareMember" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="LIXT_CommonStockParValue0.0001PerShareMember" xlink:to="LIXT_CommonStockParValue0.0001PerShareMember_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="LIXT_CommonStockParValue0.0001PerShareMember_lbl" xml:lang="en-US">Common Stock, par value $0.0001 per share</link:label>
      <link:loc xlink:type="locator" xlink:href="lixt-20221013.xsd#LIXT_WarrantsToPurchaseCommonStockParValue0.0001PerShareMember" xlink:label="LIXT_WarrantsToPurchaseCommonStockParValue0.0001PerShareMember" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="LIXT_WarrantsToPurchaseCommonStockParValue0.0001PerShareMember" xlink:to="LIXT_WarrantsToPurchaseCommonStockParValue0.0001PerShareMember_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="LIXT_WarrantsToPurchaseCommonStockParValue0.0001PerShareMember_lbl" xml:lang="en-US">Warrants to Purchase Common Stock, par value $0.0001 per share</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementTable" xlink:label="us-gaap_StatementTable" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StatementTable" xlink:to="us-gaap_StatementTable_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StatementTable_lbl" xml:lang="en-US">Statement [Table]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementLineItems" xlink:label="us-gaap_StatementLineItems" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StatementLineItems" xlink:to="us-gaap_StatementLineItems_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StatementLineItems_lbl" xml:lang="en-US">Statement [Line Items]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentType" xlink:label="dei_DocumentType" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentType" xlink:to="dei_DocumentType_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentType_lbl" xml:lang="en-US">Document Type</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_AmendmentFlag" xlink:label="dei_AmendmentFlag" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_AmendmentFlag" xlink:to="dei_AmendmentFlag_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_AmendmentFlag_lbl" xml:lang="en-US">Amendment Flag</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_AmendmentDescription" xlink:label="dei_AmendmentDescription" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_AmendmentDescription" xlink:to="dei_AmendmentDescription_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_AmendmentDescription_lbl" xml:lang="en-US">Amendment Description</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentRegistrationStatement" xlink:label="dei_DocumentRegistrationStatement" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentRegistrationStatement" xlink:to="dei_DocumentRegistrationStatement_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentRegistrationStatement_lbl" xml:lang="en-US">Document Registration Statement</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentAnnualReport" xlink:label="dei_DocumentAnnualReport" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentAnnualReport" xlink:to="dei_DocumentAnnualReport_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentAnnualReport_lbl" xml:lang="en-US">Document Annual Report</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentQuarterlyReport" xlink:label="dei_DocumentQuarterlyReport" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentQuarterlyReport" xlink:to="dei_DocumentQuarterlyReport_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentQuarterlyReport_lbl" xml:lang="en-US">Document Quarterly Report</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentTransitionReport" xlink:label="dei_DocumentTransitionReport" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentTransitionReport" xlink:to="dei_DocumentTransitionReport_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentTransitionReport_lbl" xml:lang="en-US">Document Transition Report</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentShellCompanyReport" xlink:label="dei_DocumentShellCompanyReport" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentShellCompanyReport" xlink:to="dei_DocumentShellCompanyReport_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentShellCompanyReport_lbl" xml:lang="en-US">Document Shell Company Report</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentShellCompanyEventDate" xlink:label="dei_DocumentShellCompanyEventDate" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentShellCompanyEventDate" xlink:to="dei_DocumentShellCompanyEventDate_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentShellCompanyEventDate_lbl" xml:lang="en-US">Document Shell Company Event Date</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentPeriodStartDate" xlink:label="dei_DocumentPeriodStartDate" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentPeriodStartDate" xlink:to="dei_DocumentPeriodStartDate_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentPeriodStartDate_lbl" xml:lang="en-US">Document Period Start Date</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentPeriodEndDate" xlink:label="dei_DocumentPeriodEndDate" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentPeriodEndDate" xlink:to="dei_DocumentPeriodEndDate_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentPeriodEndDate_lbl" xml:lang="en-US">Document Period End Date</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentFiscalPeriodFocus" xlink:label="dei_DocumentFiscalPeriodFocus" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentFiscalPeriodFocus" xlink:to="dei_DocumentFiscalPeriodFocus_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentFiscalPeriodFocus_lbl" xml:lang="en-US">Document Fiscal Period Focus</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentFiscalYearFocus" xlink:label="dei_DocumentFiscalYearFocus" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentFiscalYearFocus" xlink:to="dei_DocumentFiscalYearFocus_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentFiscalYearFocus_lbl" xml:lang="en-US">Document Fiscal Year Focus</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CurrentFiscalYearEndDate" xlink:label="dei_CurrentFiscalYearEndDate" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_CurrentFiscalYearEndDate" xlink:to="dei_CurrentFiscalYearEndDate_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_CurrentFiscalYearEndDate_lbl" xml:lang="en-US">Current Fiscal Year End Date</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityFileNumber" xlink:label="dei_EntityFileNumber" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityFileNumber" xlink:to="dei_EntityFileNumber_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityFileNumber_lbl" xml:lang="en-US">Entity File Number</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityRegistrantName" xlink:label="dei_EntityRegistrantName" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityRegistrantName" xlink:to="dei_EntityRegistrantName_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityRegistrantName_lbl" xml:lang="en-US">Entity Registrant Name</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityCentralIndexKey" xlink:label="dei_EntityCentralIndexKey" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityCentralIndexKey" xlink:to="dei_EntityCentralIndexKey_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityCentralIndexKey_lbl" xml:lang="en-US">Entity Central Index Key</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityPrimarySicNumber" xlink:label="dei_EntityPrimarySicNumber" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityPrimarySicNumber" xlink:to="dei_EntityPrimarySicNumber_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityPrimarySicNumber_lbl" xml:lang="en-US">Entity Primary SIC Number</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityTaxIdentificationNumber" xlink:label="dei_EntityTaxIdentificationNumber" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityTaxIdentificationNumber" xlink:to="dei_EntityTaxIdentificationNumber_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityTaxIdentificationNumber_lbl" xml:lang="en-US">Entity Tax Identification Number</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityIncorporationStateCountryCode" xlink:label="dei_EntityIncorporationStateCountryCode" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityIncorporationStateCountryCode" xlink:to="dei_EntityIncorporationStateCountryCode_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityIncorporationStateCountryCode_lbl" xml:lang="en-US">Entity Incorporation, State or Country Code</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressAddressLine1" xlink:label="dei_EntityAddressAddressLine1" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressAddressLine1" xlink:to="dei_EntityAddressAddressLine1_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityAddressAddressLine1_lbl" xml:lang="en-US">Entity Address, Address Line One</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressAddressLine2" xlink:label="dei_EntityAddressAddressLine2" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressAddressLine2" xlink:to="dei_EntityAddressAddressLine2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityAddressAddressLine2_lbl" xml:lang="en-US">Entity Address, Address Line Two</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressAddressLine3" xlink:label="dei_EntityAddressAddressLine3" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressAddressLine3" xlink:to="dei_EntityAddressAddressLine3_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityAddressAddressLine3_lbl" xml:lang="en-US">Entity Address, Address Line Three</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressCityOrTown" xlink:label="dei_EntityAddressCityOrTown" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressCityOrTown" xlink:to="dei_EntityAddressCityOrTown_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityAddressCityOrTown_lbl" xml:lang="en-US">Entity Address, City or Town</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressStateOrProvince" xlink:label="dei_EntityAddressStateOrProvince" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressStateOrProvince" xlink:to="dei_EntityAddressStateOrProvince_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityAddressStateOrProvince_lbl" xml:lang="en-US">Entity Address, State or Province</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressCountry" xlink:label="dei_EntityAddressCountry" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressCountry" xlink:to="dei_EntityAddressCountry_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityAddressCountry_lbl" xml:lang="en-US">Entity Address, Country</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressPostalZipCode" xlink:label="dei_EntityAddressPostalZipCode" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressPostalZipCode" xlink:to="dei_EntityAddressPostalZipCode_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityAddressPostalZipCode_lbl" xml:lang="en-US">Entity Address, Postal Zip Code</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CountryRegion" xlink:label="dei_CountryRegion" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_CountryRegion" xlink:to="dei_CountryRegion_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_CountryRegion_lbl" xml:lang="en-US">Country Region</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CityAreaCode" xlink:label="dei_CityAreaCode" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_CityAreaCode" xlink:to="dei_CityAreaCode_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_CityAreaCode_lbl" xml:lang="en-US">City Area Code</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_LocalPhoneNumber" xlink:label="dei_LocalPhoneNumber" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_LocalPhoneNumber" xlink:to="dei_LocalPhoneNumber_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_LocalPhoneNumber_lbl" xml:lang="en-US">Local Phone Number</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_Extension" xlink:label="dei_Extension" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_Extension" xlink:to="dei_Extension_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_Extension_lbl" xml:lang="en-US">Extension</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_WrittenCommunications" xlink:label="dei_WrittenCommunications" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_WrittenCommunications" xlink:to="dei_WrittenCommunications_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_WrittenCommunications_lbl" xml:lang="en-US">Written Communications</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_SolicitingMaterial" xlink:label="dei_SolicitingMaterial" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_SolicitingMaterial" xlink:to="dei_SolicitingMaterial_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_SolicitingMaterial_lbl" xml:lang="en-US">Soliciting Material</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_PreCommencementTenderOffer" xlink:label="dei_PreCommencementTenderOffer" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_PreCommencementTenderOffer" xlink:to="dei_PreCommencementTenderOffer_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_PreCommencementTenderOffer_lbl" xml:lang="en-US">Pre-commencement Tender Offer</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_PreCommencementIssuerTenderOffer" xlink:label="dei_PreCommencementIssuerTenderOffer" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_PreCommencementIssuerTenderOffer" xlink:to="dei_PreCommencementIssuerTenderOffer_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_PreCommencementIssuerTenderOffer_lbl" xml:lang="en-US">Pre-commencement Issuer Tender Offer</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_Security12bTitle" xlink:label="dei_Security12bTitle" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_Security12bTitle" xlink:to="dei_Security12bTitle_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_Security12bTitle_lbl" xml:lang="en-US">Title of 12(b) Security</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_NoTradingSymbolFlag" xlink:label="dei_NoTradingSymbolFlag" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_NoTradingSymbolFlag" xlink:to="dei_NoTradingSymbolFlag_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_NoTradingSymbolFlag_lbl" xml:lang="en-US">No Trading Symbol Flag</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_TradingSymbol" xlink:label="dei_TradingSymbol" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_TradingSymbol" xlink:to="dei_TradingSymbol_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_TradingSymbol_lbl" xml:lang="en-US">Trading Symbol</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_SecurityExchangeName" xlink:label="dei_SecurityExchangeName" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_SecurityExchangeName" xlink:to="dei_SecurityExchangeName_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_SecurityExchangeName_lbl" xml:lang="en-US">Security Exchange Name</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_Security12gTitle" xlink:label="dei_Security12gTitle" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_Security12gTitle" xlink:to="dei_Security12gTitle_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_Security12gTitle_lbl" xml:lang="en-US">Title of 12(g) Security</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_SecurityReportingObligation" xlink:label="dei_SecurityReportingObligation" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_SecurityReportingObligation" xlink:to="dei_SecurityReportingObligation_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_SecurityReportingObligation_lbl" xml:lang="en-US">Security Reporting Obligation</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_AnnualInformationForm" xlink:label="dei_AnnualInformationForm" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_AnnualInformationForm" xlink:to="dei_AnnualInformationForm_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_AnnualInformationForm_lbl" xml:lang="en-US">Annual Information Form</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_AuditedAnnualFinancialStatements" xlink:label="dei_AuditedAnnualFinancialStatements" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_AuditedAnnualFinancialStatements" xlink:to="dei_AuditedAnnualFinancialStatements_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_AuditedAnnualFinancialStatements_lbl" xml:lang="en-US">Audited Annual Financial Statements</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityWellKnownSeasonedIssuer" xlink:label="dei_EntityWellKnownSeasonedIssuer" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityWellKnownSeasonedIssuer" xlink:to="dei_EntityWellKnownSeasonedIssuer_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityWellKnownSeasonedIssuer_lbl" xml:lang="en-US">Entity Well-known Seasoned Issuer</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityVoluntaryFilers" xlink:label="dei_EntityVoluntaryFilers" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityVoluntaryFilers" xlink:to="dei_EntityVoluntaryFilers_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityVoluntaryFilers_lbl" xml:lang="en-US">Entity Voluntary Filers</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityCurrentReportingStatus" xlink:label="dei_EntityCurrentReportingStatus" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityCurrentReportingStatus" xlink:to="dei_EntityCurrentReportingStatus_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityCurrentReportingStatus_lbl" xml:lang="en-US">Entity Current Reporting Status</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityInteractiveDataCurrent" xlink:label="dei_EntityInteractiveDataCurrent" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityInteractiveDataCurrent" xlink:to="dei_EntityInteractiveDataCurrent_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityInteractiveDataCurrent_lbl" xml:lang="en-US">Entity Interactive Data Current</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityFilerCategory" xlink:label="dei_EntityFilerCategory" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityFilerCategory" xlink:to="dei_EntityFilerCategory_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityFilerCategory_lbl" xml:lang="en-US">Entity Filer Category</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntitySmallBusiness" xlink:label="dei_EntitySmallBusiness" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntitySmallBusiness" xlink:to="dei_EntitySmallBusiness_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntitySmallBusiness_lbl" xml:lang="en-US">Entity Small Business</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityEmergingGrowthCompany" xlink:label="dei_EntityEmergingGrowthCompany" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityEmergingGrowthCompany" xlink:to="dei_EntityEmergingGrowthCompany_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityEmergingGrowthCompany_lbl" xml:lang="en-US">Entity Emerging Growth Company</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityExTransitionPeriod" xlink:label="dei_EntityExTransitionPeriod" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityExTransitionPeriod" xlink:to="dei_EntityExTransitionPeriod_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityExTransitionPeriod_lbl" xml:lang="en-US">Elected Not To Use the Extended Transition Period</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentAccountingStandard" xlink:label="dei_DocumentAccountingStandard" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentAccountingStandard" xlink:to="dei_DocumentAccountingStandard_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentAccountingStandard_lbl" xml:lang="en-US">Document Accounting Standard</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_OtherReportingStandardItemNumber" xlink:label="dei_OtherReportingStandardItemNumber" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_OtherReportingStandardItemNumber" xlink:to="dei_OtherReportingStandardItemNumber_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_OtherReportingStandardItemNumber_lbl" xml:lang="en-US">Other Reporting Standard Item Number</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityShellCompany" xlink:label="dei_EntityShellCompany" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityShellCompany" xlink:to="dei_EntityShellCompany_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityShellCompany_lbl" xml:lang="en-US">Entity Shell Company</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityPublicFloat" xlink:label="dei_EntityPublicFloat" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityPublicFloat" xlink:to="dei_EntityPublicFloat_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityPublicFloat_lbl" xml:lang="en-US">Entity Public Float</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityBankruptcyProceedingsReportingCurrent" xlink:label="dei_EntityBankruptcyProceedingsReportingCurrent" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityBankruptcyProceedingsReportingCurrent" xlink:to="dei_EntityBankruptcyProceedingsReportingCurrent_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityBankruptcyProceedingsReportingCurrent_lbl" xml:lang="en-US">Entity Bankruptcy Proceedings, Reporting Current</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityCommonStockSharesOutstanding" xlink:label="dei_EntityCommonStockSharesOutstanding" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityCommonStockSharesOutstanding" xlink:to="dei_EntityCommonStockSharesOutstanding_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityCommonStockSharesOutstanding_lbl" xml:lang="en-US">Entity Common Stock, Shares Outstanding</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentsIncorporatedByReferenceTextBlock" xlink:label="dei_DocumentsIncorporatedByReferenceTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentsIncorporatedByReferenceTextBlock" xlink:to="dei_DocumentsIncorporatedByReferenceTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentsIncorporatedByReferenceTextBlock_lbl" xml:lang="en-US">Documents Incorporated by Reference [Text Block]</link:label>
    </link:labelLink>
</link:linkbase>
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-101.PRE
<SEQUENCE>7
<FILENAME>lixt-20221013_pre.xml
<DESCRIPTION>INLINE XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE DOCUMENT
<TEXT>
<XBRL>
<?xml version="1.0" encoding="US-ASCII" standalone="no"?>
    <!-- Field: Doc-Info; Name: Generator; Value: GoFiler Complete; Version: 5.16a -->
    <!-- Field: Doc-Info; Name: VendorURI; Value: https://www.novaworks.com -->
    <!-- Field: Doc-Info; Name: Status; Value: 0x00000000 -->
<link:linkbase xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xbrli="http://www.xbrl.org/2003/instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
    <link:roleRef roleURI="http://lixte.com/role/Cover" xlink:href="lixt-20221013.xsd#Cover" xlink:type="simple" />
    <link:presentationLink xlink:type="extended" xlink:role="http://lixte.com/role/Cover" xlink:title="00000001 - Document - Cover">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CoverAbstract" xlink:label="loc_deiCoverAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaapStatementTable" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_us-gaapStatementTable" order="100" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaapStatementLineItems" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable" xlink:to="loc_us-gaapStatementLineItems" order="200" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementClassOfStockAxis" xlink:label="loc_us-gaapStatementClassOfStockAxis" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable" xlink:to="loc_us-gaapStatementClassOfStockAxis" order="10" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfStockDomain" xlink:label="loc_us-gaapClassOfStockDomain" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementClassOfStockAxis" xlink:to="loc_us-gaapClassOfStockDomain" order="0" />
      <link:loc xlink:type="locator" xlink:href="lixt-20221013.xsd#LIXT_CommonStockParValue0.0001PerShareMember" xlink:label="loc_LIXTCommonStockParValue0.0001PerShareMember" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapClassOfStockDomain" xlink:to="loc_LIXTCommonStockParValue0.0001PerShareMember" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="lixt-20221013.xsd#LIXT_WarrantsToPurchaseCommonStockParValue0.0001PerShareMember" xlink:label="loc_LIXTWarrantsToPurchaseCommonStockParValue0.0001PerShareMember" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapClassOfStockDomain" xlink:to="loc_LIXTWarrantsToPurchaseCommonStockParValue0.0001PerShareMember" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentType" xlink:label="loc_deiDocumentType" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentType" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_AmendmentFlag" xlink:label="loc_deiAmendmentFlag" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiAmendmentFlag" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_AmendmentDescription" xlink:label="loc_deiAmendmentDescription" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiAmendmentDescription" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentRegistrationStatement" xlink:label="loc_deiDocumentRegistrationStatement" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentRegistrationStatement" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentAnnualReport" xlink:label="loc_deiDocumentAnnualReport" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentAnnualReport" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentQuarterlyReport" xlink:label="loc_deiDocumentQuarterlyReport" />
      <link:presentationArc order="50" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentQuarterlyReport" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentTransitionReport" xlink:label="loc_deiDocumentTransitionReport" />
      <link:presentationArc order="60" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentTransitionReport" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentShellCompanyReport" xlink:label="loc_deiDocumentShellCompanyReport" />
      <link:presentationArc order="70" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentShellCompanyReport" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentShellCompanyEventDate" xlink:label="loc_deiDocumentShellCompanyEventDate" />
      <link:presentationArc order="80" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentShellCompanyEventDate" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentPeriodStartDate" xlink:label="loc_deiDocumentPeriodStartDate" />
      <link:presentationArc order="90" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentPeriodStartDate" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentPeriodEndDate" xlink:label="loc_deiDocumentPeriodEndDate" />
      <link:presentationArc order="100" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentPeriodEndDate" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentFiscalPeriodFocus" xlink:label="loc_deiDocumentFiscalPeriodFocus" />
      <link:presentationArc order="110" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentFiscalPeriodFocus" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentFiscalYearFocus" xlink:label="loc_deiDocumentFiscalYearFocus" />
      <link:presentationArc order="120" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentFiscalYearFocus" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CurrentFiscalYearEndDate" xlink:label="loc_deiCurrentFiscalYearEndDate" />
      <link:presentationArc order="130" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiCurrentFiscalYearEndDate" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityFileNumber" xlink:label="loc_deiEntityFileNumber" />
      <link:presentationArc order="140" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityFileNumber" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityRegistrantName" xlink:label="loc_deiEntityRegistrantName" />
      <link:presentationArc order="150" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityRegistrantName" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityCentralIndexKey" xlink:label="loc_deiEntityCentralIndexKey" />
      <link:presentationArc order="160" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityCentralIndexKey" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityPrimarySicNumber" xlink:label="loc_deiEntityPrimarySicNumber" />
      <link:presentationArc order="170" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityPrimarySicNumber" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityTaxIdentificationNumber" xlink:label="loc_deiEntityTaxIdentificationNumber" />
      <link:presentationArc order="180" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityTaxIdentificationNumber" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityIncorporationStateCountryCode" xlink:label="loc_deiEntityIncorporationStateCountryCode" />
      <link:presentationArc order="190" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityIncorporationStateCountryCode" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressAddressLine1" xlink:label="loc_deiEntityAddressAddressLine1" />
      <link:presentationArc order="200" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityAddressAddressLine1" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressAddressLine2" xlink:label="loc_deiEntityAddressAddressLine2" />
      <link:presentationArc order="210" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityAddressAddressLine2" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressAddressLine3" xlink:label="loc_deiEntityAddressAddressLine3" />
      <link:presentationArc order="220" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityAddressAddressLine3" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressCityOrTown" xlink:label="loc_deiEntityAddressCityOrTown" />
      <link:presentationArc order="230" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityAddressCityOrTown" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressStateOrProvince" xlink:label="loc_deiEntityAddressStateOrProvince" />
      <link:presentationArc order="240" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityAddressStateOrProvince" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressCountry" xlink:label="loc_deiEntityAddressCountry" />
      <link:presentationArc order="250" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityAddressCountry" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressPostalZipCode" xlink:label="loc_deiEntityAddressPostalZipCode" />
      <link:presentationArc order="260" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityAddressPostalZipCode" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CountryRegion" xlink:label="loc_deiCountryRegion" />
      <link:presentationArc order="270" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiCountryRegion" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CityAreaCode" xlink:label="loc_deiCityAreaCode" />
      <link:presentationArc order="280" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiCityAreaCode" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_LocalPhoneNumber" xlink:label="loc_deiLocalPhoneNumber" />
      <link:presentationArc order="290" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiLocalPhoneNumber" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_Extension" xlink:label="loc_deiExtension" />
      <link:presentationArc order="300" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiExtension" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_WrittenCommunications" xlink:label="loc_deiWrittenCommunications" />
      <link:presentationArc order="310" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiWrittenCommunications" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_SolicitingMaterial" xlink:label="loc_deiSolicitingMaterial" />
      <link:presentationArc order="320" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiSolicitingMaterial" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_PreCommencementTenderOffer" xlink:label="loc_deiPreCommencementTenderOffer" />
      <link:presentationArc order="330" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiPreCommencementTenderOffer" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_PreCommencementIssuerTenderOffer" xlink:label="loc_deiPreCommencementIssuerTenderOffer" />
      <link:presentationArc order="340" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiPreCommencementIssuerTenderOffer" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_Security12bTitle" xlink:label="loc_deiSecurity12bTitle" />
      <link:presentationArc order="350" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiSecurity12bTitle" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_NoTradingSymbolFlag" xlink:label="loc_deiNoTradingSymbolFlag" />
      <link:presentationArc order="360" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiNoTradingSymbolFlag" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_TradingSymbol" xlink:label="loc_deiTradingSymbol" />
      <link:presentationArc order="370" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiTradingSymbol" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_SecurityExchangeName" xlink:label="loc_deiSecurityExchangeName" />
      <link:presentationArc order="380" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiSecurityExchangeName" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_Security12gTitle" xlink:label="loc_deiSecurity12gTitle" />
      <link:presentationArc order="390" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiSecurity12gTitle" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_SecurityReportingObligation" xlink:label="loc_deiSecurityReportingObligation" />
      <link:presentationArc order="400" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiSecurityReportingObligation" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_AnnualInformationForm" xlink:label="loc_deiAnnualInformationForm" />
      <link:presentationArc order="410" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiAnnualInformationForm" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_AuditedAnnualFinancialStatements" xlink:label="loc_deiAuditedAnnualFinancialStatements" />
      <link:presentationArc order="420" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiAuditedAnnualFinancialStatements" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityWellKnownSeasonedIssuer" xlink:label="loc_deiEntityWellKnownSeasonedIssuer" />
      <link:presentationArc order="430" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityWellKnownSeasonedIssuer" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityVoluntaryFilers" xlink:label="loc_deiEntityVoluntaryFilers" />
      <link:presentationArc order="440" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityVoluntaryFilers" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityCurrentReportingStatus" xlink:label="loc_deiEntityCurrentReportingStatus" />
      <link:presentationArc order="450" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityCurrentReportingStatus" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityInteractiveDataCurrent" xlink:label="loc_deiEntityInteractiveDataCurrent" />
      <link:presentationArc order="460" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityInteractiveDataCurrent" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityFilerCategory" xlink:label="loc_deiEntityFilerCategory" />
      <link:presentationArc order="470" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityFilerCategory" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntitySmallBusiness" xlink:label="loc_deiEntitySmallBusiness" />
      <link:presentationArc order="480" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntitySmallBusiness" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityEmergingGrowthCompany" xlink:label="loc_deiEntityEmergingGrowthCompany" />
      <link:presentationArc order="490" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityEmergingGrowthCompany" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityExTransitionPeriod" xlink:label="loc_deiEntityExTransitionPeriod" />
      <link:presentationArc order="500" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityExTransitionPeriod" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentAccountingStandard" xlink:label="loc_deiDocumentAccountingStandard" />
      <link:presentationArc order="510" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentAccountingStandard" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_OtherReportingStandardItemNumber" xlink:label="loc_deiOtherReportingStandardItemNumber" />
      <link:presentationArc order="520" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiOtherReportingStandardItemNumber" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityShellCompany" xlink:label="loc_deiEntityShellCompany" />
      <link:presentationArc order="530" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityShellCompany" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityPublicFloat" xlink:label="loc_deiEntityPublicFloat" />
      <link:presentationArc order="540" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityPublicFloat" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityBankruptcyProceedingsReportingCurrent" xlink:label="loc_deiEntityBankruptcyProceedingsReportingCurrent" />
      <link:presentationArc order="550" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityBankruptcyProceedingsReportingCurrent" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityCommonStockSharesOutstanding" xlink:label="loc_deiEntityCommonStockSharesOutstanding" />
      <link:presentationArc order="560" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiEntityCommonStockSharesOutstanding" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentsIncorporatedByReferenceTextBlock" xlink:label="loc_deiDocumentsIncorporatedByReferenceTextBlock" />
      <link:presentationArc order="570" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_deiDocumentsIncorporatedByReferenceTextBlock" xlink:type="arc" />
    </link:presentationLink>
</link:linkbase>
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>8
<FILENAME>R1.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.22.2.2</span><table class="report" border="0" cellspacing="2" id="idm139836319740832">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Cover<br></strong></div></th>
<th class="th"><div>Oct. 13, 2022</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_DocumentType', window );">Document Type</a></td>
<td class="text">8-K<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_AmendmentFlag', window );">Amendment Flag</a></td>
<td class="text">false<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_DocumentPeriodEndDate', window );">Document Period End Date</a></td>
<td class="text">Oct. 13,  2022<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityFileNumber', window );">Entity File Number</a></td>
<td class="text">001-39717<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityRegistrantName', window );">Entity Registrant Name</a></td>
<td class="text">LIXTE
BIOTECHNOLOGY HOLDINGS, INC.<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityCentralIndexKey', window );">Entity Central Index Key</a></td>
<td class="text">0001335105<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityTaxIdentificationNumber', window );">Entity Tax Identification Number</a></td>
<td class="text">20-2903526<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityIncorporationStateCountryCode', window );">Entity Incorporation, State or Country Code</a></td>
<td class="text">DE<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityAddressAddressLine1', window );">Entity Address, Address Line One</a></td>
<td class="text">680
East Colorado Boulevard<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityAddressAddressLine2', window );">Entity Address, Address Line Two</a></td>
<td class="text">Suite 180<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityAddressCityOrTown', window );">Entity Address, City or Town</a></td>
<td class="text">Pasadena<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityAddressStateOrProvince', window );">Entity Address, State or Province</a></td>
<td class="text">CA<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityAddressPostalZipCode', window );">Entity Address, Postal Zip Code</a></td>
<td class="text">91101<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_CityAreaCode', window );">City Area Code</a></td>
<td class="text">(631)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_LocalPhoneNumber', window );">Local Phone Number</a></td>
<td class="text">830-7092<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_WrittenCommunications', window );">Written Communications</a></td>
<td class="text">false<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_SolicitingMaterial', window );">Soliciting Material</a></td>
<td class="text">false<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_PreCommencementTenderOffer', window );">Pre-commencement Tender Offer</a></td>
<td class="text">false<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_PreCommencementIssuerTenderOffer', window );">Pre-commencement Issuer Tender Offer</a></td>
<td class="text">false<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StatementClassOfStockAxis=LIXT_CommonStockParValue0.0001PerShareMember', window );">Common Stock, par value $0.0001 per share</a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_Security12bTitle', window );">Title of 12(b) Security</a></td>
<td class="text">Common
    Stock, par value $0.0001 per share<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_TradingSymbol', window );">Trading Symbol</a></td>
<td class="text">LIXT<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_SecurityExchangeName', window );">Security Exchange Name</a></td>
<td class="text">NASDAQ<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StatementClassOfStockAxis=LIXT_WarrantsToPurchaseCommonStockParValue0.0001PerShareMember', window );">Warrants to Purchase Common Stock, par value $0.0001 per share</a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_Security12bTitle', window );">Title of 12(b) Security</a></td>
<td class="text">Warrants
    to Purchase Common Stock, par value $0.0001 per share<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_TradingSymbol', window );">Trading Symbol</a></td>
<td class="text">LIXTW<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_SecurityExchangeName', window );">Security Exchange Name</a></td>
<td class="text">NASDAQ<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_AmendmentFlag">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the XBRL content amends previously-filed or accepted submission.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_AmendmentFlag</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_CityAreaCode">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Area code of city</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_CityAreaCode</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentPeriodEndDate">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>For the EDGAR submission types of Form 8-K: the date of the report, the date of the earliest event reported; for the EDGAR submission types of Form N-1A: the filing date; for all other submission types: the end of the reporting or transition period.  The format of the date is YYYY-MM-DD.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentPeriodEndDate</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:dateItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentType">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The type of document being provided (such as 10-K, 10-Q, 485BPOS, etc). The document type is limited to the same value as the supporting SEC submission type, or the word 'Other'.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentType</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:submissionTypeItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressAddressLine1">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Address Line 1 such as Attn, Building Name, Street Name</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressAddressLine1</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressAddressLine2">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Address Line 2 such as Street or Suite number</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressAddressLine2</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressCityOrTown">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Name of the City or Town</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressCityOrTown</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressPostalZipCode">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Code for the postal or zip code</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressPostalZipCode</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressStateOrProvince">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Name of the state or province.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressStateOrProvince</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:stateOrProvinceItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityCentralIndexKey">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>A unique 10-digit SEC-issued value to identify entities that have filed disclosures with the SEC. It is commonly abbreviated as CIK.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityCentralIndexKey</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:centralIndexKeyItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityFileNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Commission file number. The field allows up to 17 characters. The prefix may contain 1-3 digits, the sequence number may contain 1-8 digits, the optional suffix may contain 1-4 characters, and the fields are separated with a hyphen.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityFileNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:fileNumberItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityIncorporationStateCountryCode">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Two-character EDGAR code representing the state or country of incorporation.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityIncorporationStateCountryCode</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:edgarStateCountryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityRegistrantName">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The exact name of the entity filing the report as specified in its charter, which is required by forms filed with the SEC.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityRegistrantName</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityTaxIdentificationNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The Tax Identification Number (TIN), also known as an Employer Identification Number (EIN), is a unique 9-digit value assigned by the IRS.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityTaxIdentificationNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:employerIdItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_LocalPhoneNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Local phone number for entity.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_LocalPhoneNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_PreCommencementIssuerTenderOffer">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 13e<br> -Subsection 4c<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_PreCommencementIssuerTenderOffer</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_PreCommencementTenderOffer">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 14d<br> -Subsection 2b<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_PreCommencementTenderOffer</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_Security12bTitle">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Title of a 12(b) registered security.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection b<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_Security12bTitle</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:securityTitleItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_SecurityExchangeName">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Name of the Exchange on which a security is registered.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection d1-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_SecurityExchangeName</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:edgarExchangeCodeItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_SolicitingMaterial">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as soliciting material pursuant to Rule 14a-12 under the Exchange Act.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Section 14a<br> -Number 240<br> -Subsection 12<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_SolicitingMaterial</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_TradingSymbol">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Trading symbol of an instrument as listed on an exchange.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_TradingSymbol</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:tradingSymbolItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_WrittenCommunications">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as written communications pursuant to Rule 425 under the Securities Act.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Securities Act<br> -Number 230<br> -Section 425<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_WrittenCommunications</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StatementClassOfStockAxis=LIXT_CommonStockParValue0.0001PerShareMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StatementClassOfStockAxis=LIXT_CommonStockParValue0.0001PerShareMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StatementClassOfStockAxis=LIXT_WarrantsToPurchaseCommonStockParValue0.0001PerShareMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StatementClassOfStockAxis=LIXT_WarrantsToPurchaseCommonStockParValue0.0001PerShareMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>9
<FILENAME>form8-k_htm.xml
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<XML>
<?xml version="1.0" encoding="utf-8"?>
<xbrl
  xmlns="http://www.xbrl.org/2003/instance"
  xmlns:LIXT="http://lixte.com/20221013"
  xmlns:dei="http://xbrl.sec.gov/dei/2022"
  xmlns:iso4217="http://www.xbrl.org/2003/iso4217"
  xmlns:link="http://www.xbrl.org/2003/linkbase"
  xmlns:us-gaap="http://fasb.org/us-gaap/2022"
  xmlns:xbrldi="http://xbrl.org/2006/xbrldi"
  xmlns:xlink="http://www.w3.org/1999/xlink">
    <link:schemaRef xlink:href="lixt-20221013.xsd" xlink:type="simple"/>
    <context id="From2022-10-13to2022-10-13">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001335105</identifier>
        </entity>
        <period>
            <startDate>2022-10-13</startDate>
            <endDate>2022-10-13</endDate>
        </period>
    </context>
    <context id="From2022-10-132022-10-13_custom_CommonStockParValue0.0001PerShareMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001335105</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">LIXT:CommonStockParValue0.0001PerShareMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-13</startDate>
            <endDate>2022-10-13</endDate>
        </period>
    </context>
    <context id="From2022-10-132022-10-13_custom_WarrantsToPurchaseCommonStockParValue0.0001PerShareMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001335105</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">LIXT:WarrantsToPurchaseCommonStockParValue0.0001PerShareMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-13</startDate>
            <endDate>2022-10-13</endDate>
        </period>
    </context>
    <unit id="USD">
        <measure>iso4217:USD</measure>
    </unit>
    <unit id="Shares">
        <measure>shares</measure>
    </unit>
    <unit id="USDPShares">
        <divide>
            <unitNumerator>
                <measure>iso4217:USD</measure>
            </unitNumerator>
            <unitDenominator>
                <measure>shares</measure>
            </unitDenominator>
        </divide>
    </unit>
    <dei:EntityCentralIndexKey contextRef="From2022-10-13to2022-10-13">0001335105</dei:EntityCentralIndexKey>
    <dei:AmendmentFlag contextRef="From2022-10-13to2022-10-13">false</dei:AmendmentFlag>
    <dei:DocumentType contextRef="From2022-10-13to2022-10-13">8-K</dei:DocumentType>
    <dei:DocumentPeriodEndDate contextRef="From2022-10-13to2022-10-13">2022-10-13</dei:DocumentPeriodEndDate>
    <dei:EntityRegistrantName contextRef="From2022-10-13to2022-10-13">LIXTE BIOTECHNOLOGY HOLDINGS, INC.</dei:EntityRegistrantName>
    <dei:EntityIncorporationStateCountryCode contextRef="From2022-10-13to2022-10-13">DE</dei:EntityIncorporationStateCountryCode>
    <dei:EntityFileNumber contextRef="From2022-10-13to2022-10-13">001-39717</dei:EntityFileNumber>
    <dei:EntityTaxIdentificationNumber contextRef="From2022-10-13to2022-10-13">20-2903526</dei:EntityTaxIdentificationNumber>
    <dei:EntityAddressAddressLine1 contextRef="From2022-10-13to2022-10-13">680 East Colorado Boulevard</dei:EntityAddressAddressLine1>
    <dei:EntityAddressAddressLine2 contextRef="From2022-10-13to2022-10-13">Suite 180</dei:EntityAddressAddressLine2>
    <dei:EntityAddressCityOrTown contextRef="From2022-10-13to2022-10-13">Pasadena</dei:EntityAddressCityOrTown>
    <dei:EntityAddressStateOrProvince contextRef="From2022-10-13to2022-10-13">CA</dei:EntityAddressStateOrProvince>
    <dei:EntityAddressPostalZipCode contextRef="From2022-10-13to2022-10-13">91101</dei:EntityAddressPostalZipCode>
    <dei:CityAreaCode contextRef="From2022-10-13to2022-10-13">(631)</dei:CityAreaCode>
    <dei:LocalPhoneNumber contextRef="From2022-10-13to2022-10-13">830-7092</dei:LocalPhoneNumber>
    <dei:WrittenCommunications contextRef="From2022-10-13to2022-10-13">false</dei:WrittenCommunications>
    <dei:SolicitingMaterial contextRef="From2022-10-13to2022-10-13">false</dei:SolicitingMaterial>
    <dei:PreCommencementTenderOffer contextRef="From2022-10-13to2022-10-13">false</dei:PreCommencementTenderOffer>
    <dei:PreCommencementIssuerTenderOffer contextRef="From2022-10-13to2022-10-13">false</dei:PreCommencementIssuerTenderOffer>
    <dei:Security12bTitle contextRef="From2022-10-132022-10-13_custom_CommonStockParValue0.0001PerShareMember">Common     Stock, par value $0.0001 per share</dei:Security12bTitle>
    <dei:TradingSymbol contextRef="From2022-10-132022-10-13_custom_CommonStockParValue0.0001PerShareMember">LIXT</dei:TradingSymbol>
    <dei:SecurityExchangeName contextRef="From2022-10-132022-10-13_custom_CommonStockParValue0.0001PerShareMember">NASDAQ</dei:SecurityExchangeName>
    <dei:Security12bTitle contextRef="From2022-10-132022-10-13_custom_WarrantsToPurchaseCommonStockParValue0.0001PerShareMember">Warrants     to Purchase Common Stock, par value $0.0001 per share</dei:Security12bTitle>
    <dei:TradingSymbol contextRef="From2022-10-132022-10-13_custom_WarrantsToPurchaseCommonStockParValue0.0001PerShareMember">LIXTW</dei:TradingSymbol>
    <dei:SecurityExchangeName contextRef="From2022-10-132022-10-13_custom_WarrantsToPurchaseCommonStockParValue0.0001PerShareMember">NASDAQ</dei:SecurityExchangeName>
</xbrl>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EXCEL
<SEQUENCE>10
<FILENAME>Financial_Report.xlsx
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
begin 644 Financial_Report.xlsx
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M")Q&',$8  <,2=/^/7CW/DK&]U1R^8^P^0E02P,$%     @ R6E259>*NQS
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M4$L! A0#%     @ R6E250=!36*!    L0   !               ( !
M &1O8U!R;W!S+V%P<"YX;6Q02P$"% ,4    " #):5)5S#PKQ>X    K @
M$0              @ &O    9&]C4')O<',O8V]R92YX;6Q02P$"% ,4
M" #):5)5F5R<(Q &  "<)P  $P              @ ', 0  >&PO=&AE;64O
M=&AE;64Q+GAM;%!+ 0(4 Q0    ( ,EI4E6'%LK^IP0  'D3   8
M      " @0T(  !X;"]W;W)K<VAE971S+W-H965T,2YX;6Q02P$"% ,4
M" #):5)5X/0ZB:H"   P#   #0              @ 'J#   >&PO<W1Y;&5S
M+GAM;%!+ 0(4 Q0    ( ,EI4E67BKL<P    !,"   +              "
M ;\/  !?<F5L<R\N<F5L<U!+ 0(4 Q0    ( ,EI4E6JQ"(6,P$  "("   /
M              "  :@0  !X;"]W;W)K8F]O:RYX;6Q02P$"% ,4    " #)
M:5)5)!Z;HJT   #X 0  &@              @ $($@  >&PO7W)E;',O=V]R
M:V)O;VLN>&UL+G)E;'-02P$"% ,4    " #):5)599!YDAD!  #/ P  $P
M            @ 'M$@  6T-O;G1E;G1?5'EP97-=+GAM;%!+!08     "0 )
+ #X"   W%      !

end
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>11
<FILENAME>Show.js
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
// Edgar(tm) Renderer was created by staff of the U.S. Securities and Exchange Commission.  Data and content created by government employees within the scope of their employment are not subject to domestic copyright protection. 17 U.S.C. 105.
var Show={};Show.LastAR=null,Show.showAR=function(a,r,w){if(Show.LastAR)Show.hideAR();var e=a;while(e&&e.nodeName!='TABLE')e=e.nextSibling;if(!e||e.nodeName!='TABLE'){var ref=((window)?w.document:document).getElementById(r);if(ref){e=ref.cloneNode(!0);
e.removeAttribute('id');a.parentNode.appendChild(e)}}
if(e)e.style.display='block';Show.LastAR=e};Show.hideAR=function(){Show.LastAR.style.display='none'};Show.toggleNext=function(a){var e=a;while(e.nodeName!='DIV')e=e.nextSibling;if(!e.style){}else if(!e.style.display){}else{var d,p_;if(e.style.display=='none'){d='block';p='-'}else{d='none';p='+'}
e.style.display=d;if(a.textContent){a.textContent=p+a.textContent.substring(1)}else{a.innerText=p+a.innerText.substring(1)}}}
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>12
<FILENAME>report.css
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
/* Updated 2009-11-04 */
/* v2.2.0.24 */

/* DefRef Styles */
..report table.authRefData{
	background-color: #def;
	border: 2px solid #2F4497;
	font-size: 1em;
	position: absolute;
}

..report table.authRefData a {
	display: block;
	font-weight: bold;
}

..report table.authRefData p {
	margin-top: 0px;
}

..report table.authRefData .hide {
	background-color: #2F4497;
	padding: 1px 3px 0px 0px;
	text-align: right;
}

..report table.authRefData .hide a:hover {
	background-color: #2F4497;
}

..report table.authRefData .body {
	height: 150px;
	overflow: auto;
	width: 400px;
}

..report table.authRefData table{
	font-size: 1em;
}

/* Report Styles */
..pl a, .pl a:visited {
	color: black;
	text-decoration: none;
}

/* table */
..report {
	background-color: white;
	border: 2px solid #acf;
	clear: both;
	color: black;
	font: normal 8pt Helvetica, Arial, san-serif;
	margin-bottom: 2em;
}

..report hr {
	border: 1px solid #acf;
}

/* Top labels */
..report th {
	background-color: #acf;
	color: black;
	font-weight: bold;
	text-align: center;
}

..report th.void	{
	background-color: transparent;
	color: #000000;
	font: bold 10pt Helvetica, Arial, san-serif;
	text-align: left;
}

..report .pl {
	text-align: left;
	vertical-align: top;
	white-space: normal;
	width: 200px;
	white-space: normal; /* word-wrap: break-word; */
}

..report td.pl a.a {
	cursor: pointer;
	display: block;
	width: 200px;
	overflow: hidden;
}

..report td.pl div.a {
	width: 200px;
}

..report td.pl a:hover {
	background-color: #ffc;
}

/* Header rows... */
..report tr.rh {
	background-color: #acf;
	color: black;
	font-weight: bold;
}

/* Calendars... */
..report .rc {
	background-color: #f0f0f0;
}

/* Even rows... */
..report .re, .report .reu {
	background-color: #def;
}

..report .reu td {
	border-bottom: 1px solid black;
}

/* Odd rows... */
..report .ro, .report .rou {
	background-color: white;
}

..report .rou td {
	border-bottom: 1px solid black;
}

..report .rou table td, .report .reu table td {
	border-bottom: 0px solid black;
}

/* styles for footnote marker */
..report .fn {
	white-space: nowrap;
}

/* styles for numeric types */
..report .num, .report .nump {
	text-align: right;
	white-space: nowrap;
}

..report .nump {
	padding-left: 2em;
}

..report .nump {
	padding: 0px 0.4em 0px 2em;
}

/* styles for text types */
..report .text {
	text-align: left;
	white-space: normal;
}

..report .text .big {
	margin-bottom: 1em;
	width: 17em;
}

..report .text .more {
	display: none;
}

..report .text .note {
	font-style: italic;
	font-weight: bold;
}

..report .text .small {
	width: 10em;
}

..report sup {
	font-style: italic;
}

..report .outerFootnotes {
	font-size: 1em;
}
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>13
<FILENAME>FilingSummary.xml
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<XML>
<?xml version='1.0' encoding='utf-8'?>
<FilingSummary>
  <Version>3.22.2.2</Version>
  <ProcessingTime/>
  <ReportFormat>html</ReportFormat>
  <ContextCount>3</ContextCount>
  <ElementCount>22</ElementCount>
  <EntityCount>1</EntityCount>
  <FootnotesReported>false</FootnotesReported>
  <SegmentCount>2</SegmentCount>
  <ScenarioCount>0</ScenarioCount>
  <TuplesReported>false</TuplesReported>
  <UnitCount>3</UnitCount>
  <MyReports>
    <Report instance="form8-k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R1.htm</HtmlFileName>
      <LongName>00000001 - Document - Cover</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://lixte.com/role/Cover</Role>
      <ShortName>Cover</ShortName>
      <MenuCategory>Cover</MenuCategory>
      <Position>1</Position>
    </Report>
    <Report>
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <LongName>All Reports</LongName>
      <ReportType>Book</ReportType>
      <ShortName>All Reports</ShortName>
    </Report>
  </MyReports>
  <Logs>
    <Log type="Warning">[dq-0540-EntityEmergingGrowthCompany-Missing] Submission type 8-K should have a non-empty value for EntityEmergingGrowthCompany in the Required Context. form8-k.htm </Log>
  </Logs>
  <InputFiles>
    <File doctype="8-K" original="form8-k.htm">form8-k.htm</File>
    <File>ex99-1.htm</File>
    <File>lixt-20221013.xsd</File>
    <File>lixt-20221013_def.xml</File>
    <File>lixt-20221013_lab.xml</File>
    <File>lixt-20221013_pre.xml</File>
  </InputFiles>
  <SupplementalFiles/>
  <BaseTaxonomies>
    <BaseTaxonomy items="25">http://xbrl.sec.gov/dei/2022</BaseTaxonomy>
  </BaseTaxonomies>
  <HasPresentationLinkbase>true</HasPresentationLinkbase>
  <HasCalculationLinkbase>false</HasCalculationLinkbase>
</FilingSummary>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>JSON
<SEQUENCE>16
<FILENAME>MetaLinks.json
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
{
 "instance": {
  "form8-k.htm": {
   "axisCustom": 0,
   "axisStandard": 1,
   "contextCount": 3,
   "dts": {
    "definitionLink": {
     "local": [
      "lixt-20221013_def.xml"
     ]
    },
    "inline": {
     "local": [
      "form8-k.htm"
     ]
    },
    "labelLink": {
     "local": [
      "lixt-20221013_lab.xml"
     ]
    },
    "presentationLink": {
     "local": [
      "lixt-20221013_pre.xml"
     ]
    },
    "schema": {
     "local": [
      "lixt-20221013.xsd"
     ],
     "remote": [
      "http://www.xbrl.org/2003/xbrl-instance-2003-12-31.xsd",
      "http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd",
      "http://www.xbrl.org/2003/xl-2003-12-31.xsd",
      "http://www.xbrl.org/2003/xlink-2003-12-31.xsd",
      "http://www.xbrl.org/2005/xbrldt-2005.xsd",
      "http://www.xbrl.org/2006/ref-2006-02-27.xsd",
      "http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd",
      "http://www.xbrl.org/lrr/role/net-2009-12-16.xsd",
      "https://www.xbrl.org/2020/extensible-enumerations-2.0.xsd",
      "https://www.xbrl.org/dtr/type/2020-01-21/types.xsd",
      "https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd",
      "https://xbrl.fasb.org/srt/2022/elts/srt-roles-2022.xsd",
      "https://xbrl.fasb.org/srt/2022/elts/srt-types-2022.xsd",
      "https://xbrl.fasb.org/srt/2022q3/srt-sup-2022q3.xsd",
      "https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd",
      "https://xbrl.fasb.org/us-gaap/2022/elts/us-roles-2022.xsd",
      "https://xbrl.fasb.org/us-gaap/2022/elts/us-types-2022.xsd",
      "https://xbrl.fasb.org/us-gaap/2022q3/us-gaap-sup-2022q3.xsd",
      "https://xbrl.sec.gov/country/2022/country-2022.xsd",
      "https://xbrl.sec.gov/dei/2022/dei-2022.xsd"
     ]
    }
   },
   "elementCount": 65,
   "entityCount": 1,
   "hidden": {
    "http://xbrl.sec.gov/dei/2022": 2,
    "total": 2
   },
   "keyCustom": 0,
   "keyStandard": 22,
   "memberCustom": 2,
   "memberStandard": 0,
   "nsprefix": "LIXT",
   "nsuri": "http://lixte.com/20221013",
   "report": {
    "R1": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "span",
       "p",
       "body",
       "html"
      ],
      "baseRef": "form8-k.htm",
      "contextRef": "From2022-10-13to2022-10-13",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "dei:DocumentType",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "document",
     "isDefault": "true",
     "longName": "00000001 - Document - Cover",
     "role": "http://lixte.com/role/Cover",
     "shortName": "Cover",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "span",
       "p",
       "body",
       "html"
      ],
      "baseRef": "form8-k.htm",
      "contextRef": "From2022-10-13to2022-10-13",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "dei:DocumentType",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    }
   },
   "segmentCount": 2,
   "tag": {
    "LIXT_CommonStockParValue0.0001PerShareMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Common Stock, par value $0.0001 per share"
       }
      }
     },
     "localname": "CommonStockParValue0.0001PerShareMember",
     "nsuri": "http://lixte.com/20221013",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "domainItemType"
    },
    "LIXT_WarrantsToPurchaseCommonStockParValue0.0001PerShareMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Warrants to Purchase Common Stock, par value $0.0001 per share"
       }
      }
     },
     "localname": "WarrantsToPurchaseCommonStockParValue0.0001PerShareMember",
     "nsuri": "http://lixte.com/20221013",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "domainItemType"
    },
    "dei_AmendmentDescription": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Description of changes contained within amended document.",
        "label": "Amendment Description"
       }
      }
     },
     "localname": "AmendmentDescription",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "stringItemType"
    },
    "dei_AmendmentFlag": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true when the XBRL content amends previously-filed or accepted submission.",
        "label": "Amendment Flag"
       }
      }
     },
     "localname": "AmendmentFlag",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_AnnualInformationForm": {
     "auth_ref": [
      "r14"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag with value true on a form if it is an annual report containing an annual information form.",
        "label": "Annual Information Form"
       }
      }
     },
     "localname": "AnnualInformationForm",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_AuditedAnnualFinancialStatements": {
     "auth_ref": [
      "r14"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag with value true on a form if it is an annual report containing audited financial statements.",
        "label": "Audited Annual Financial Statements"
       }
      }
     },
     "localname": "AuditedAnnualFinancialStatements",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_CityAreaCode": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Area code of city",
        "label": "City Area Code"
       }
      }
     },
     "localname": "CityAreaCode",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_CountryRegion": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Region code of country",
        "label": "Country Region"
       }
      }
     },
     "localname": "CountryRegion",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_CoverAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Cover page."
       }
      }
     },
     "localname": "CoverAbstract",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "xbrltype": "stringItemType"
    },
    "dei_CurrentFiscalYearEndDate": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "End date of current fiscal year in the format --MM-DD.",
        "label": "Current Fiscal Year End Date"
       }
      }
     },
     "localname": "CurrentFiscalYearEndDate",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "gMonthDayItemType"
    },
    "dei_DocumentAccountingStandard": {
     "auth_ref": [
      "r13"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The basis of accounting the registrant has used to prepare the financial statements included in this filing This can either be 'U.S. GAAP', 'International Financial Reporting Standards', or 'Other'.",
        "label": "Document Accounting Standard"
       }
      }
     },
     "localname": "DocumentAccountingStandard",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "accountingStandardItemType"
    },
    "dei_DocumentAnnualReport": {
     "auth_ref": [
      "r11",
      "r13",
      "r14"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true only for a form used as an annual report.",
        "label": "Document Annual Report"
       }
      }
     },
     "localname": "DocumentAnnualReport",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_DocumentFiscalPeriodFocus": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Fiscal period values are FY, Q1, Q2, and Q3.  1st, 2nd and 3rd quarter 10-Q or 10-QT statements have value Q1, Q2, and Q3 respectively, with 10-K, 10-KT or other fiscal year statements having FY.",
        "label": "Document Fiscal Period Focus"
       }
      }
     },
     "localname": "DocumentFiscalPeriodFocus",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "fiscalPeriodItemType"
    },
    "dei_DocumentFiscalYearFocus": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "This is focus fiscal year of the document report in YYYY format. For a 2006 annual report, which may also provide financial information from prior periods, fiscal 2006 should be given as the fiscal year focus. Example: 2006.",
        "label": "Document Fiscal Year Focus"
       }
      }
     },
     "localname": "DocumentFiscalYearFocus",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "gYearItemType"
    },
    "dei_DocumentPeriodEndDate": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "For the EDGAR submission types of Form 8-K: the date of the report, the date of the earliest event reported; for the EDGAR submission types of Form N-1A: the filing date; for all other submission types: the end of the reporting or transition period.  The format of the date is YYYY-MM-DD.",
        "label": "Document Period End Date"
       }
      }
     },
     "localname": "DocumentPeriodEndDate",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "dateItemType"
    },
    "dei_DocumentPeriodStartDate": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The start date of the period covered in the document, in YYYY-MM-DD format.",
        "label": "Document Period Start Date"
       }
      }
     },
     "localname": "DocumentPeriodStartDate",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "dateItemType"
    },
    "dei_DocumentQuarterlyReport": {
     "auth_ref": [
      "r12"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true only for a form used as an quarterly report.",
        "label": "Document Quarterly Report"
       }
      }
     },
     "localname": "DocumentQuarterlyReport",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_DocumentRegistrationStatement": {
     "auth_ref": [
      "r0"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true only for a form used as a registration statement.",
        "label": "Document Registration Statement"
       }
      }
     },
     "localname": "DocumentRegistrationStatement",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_DocumentShellCompanyEventDate": {
     "auth_ref": [
      "r13"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Date of event requiring a shell company report.",
        "label": "Document Shell Company Event Date"
       }
      }
     },
     "localname": "DocumentShellCompanyEventDate",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "dateItemType"
    },
    "dei_DocumentShellCompanyReport": {
     "auth_ref": [
      "r13"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true for a Shell Company Report pursuant to section 13 or 15(d) of the Exchange Act.",
        "label": "Document Shell Company Report"
       }
      }
     },
     "localname": "DocumentShellCompanyReport",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_DocumentTransitionReport": {
     "auth_ref": [
      "r15"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true only for a form used as a transition report.",
        "label": "Document Transition Report"
       }
      }
     },
     "localname": "DocumentTransitionReport",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_DocumentType": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The type of document being provided (such as 10-K, 10-Q, 485BPOS, etc). The document type is limited to the same value as the supporting SEC submission type, or the word 'Other'.",
        "label": "Document Type"
       }
      }
     },
     "localname": "DocumentType",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "submissionTypeItemType"
    },
    "dei_DocumentsIncorporatedByReferenceTextBlock": {
     "auth_ref": [
      "r3"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Documents incorporated by reference.",
        "label": "Documents Incorporated by Reference [Text Block]"
       }
      }
     },
     "localname": "DocumentsIncorporatedByReferenceTextBlock",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "textBlockItemType"
    },
    "dei_EntityAddressAddressLine1": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Address Line 1 such as Attn, Building Name, Street Name",
        "label": "Entity Address, Address Line One"
       }
      }
     },
     "localname": "EntityAddressAddressLine1",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_EntityAddressAddressLine2": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Address Line 2 such as Street or Suite number",
        "label": "Entity Address, Address Line Two"
       }
      }
     },
     "localname": "EntityAddressAddressLine2",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_EntityAddressAddressLine3": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Address Line 3 such as an Office Park",
        "label": "Entity Address, Address Line Three"
       }
      }
     },
     "localname": "EntityAddressAddressLine3",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_EntityAddressCityOrTown": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Name of the City or Town",
        "label": "Entity Address, City or Town"
       }
      }
     },
     "localname": "EntityAddressCityOrTown",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_EntityAddressCountry": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "ISO 3166-1 alpha-2 country code.",
        "label": "Entity Address, Country"
       }
      }
     },
     "localname": "EntityAddressCountry",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "countryCodeItemType"
    },
    "dei_EntityAddressPostalZipCode": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Code for the postal or zip code",
        "label": "Entity Address, Postal Zip Code"
       }
      }
     },
     "localname": "EntityAddressPostalZipCode",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_EntityAddressStateOrProvince": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Name of the state or province.",
        "label": "Entity Address, State or Province"
       }
      }
     },
     "localname": "EntityAddressStateOrProvince",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "stateOrProvinceItemType"
    },
    "dei_EntityBankruptcyProceedingsReportingCurrent": {
     "auth_ref": [
      "r6"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "For registrants involved in bankruptcy proceedings during the preceding five years, the value Yes indicates that the registrant has filed all documents and reports required to be filed by Section 12, 13 or 15(d) of the Securities Exchange Act of 1934 subsequent to the distribution of securities under a plan confirmed by a court; the value No indicates the registrant has not.  Registrants not involved in bankruptcy proceedings during the preceding five years should not report this element.",
        "label": "Entity Bankruptcy Proceedings, Reporting Current"
       }
      }
     },
     "localname": "EntityBankruptcyProceedingsReportingCurrent",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_EntityCentralIndexKey": {
     "auth_ref": [
      "r2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "A unique 10-digit SEC-issued value to identify entities that have filed disclosures with the SEC. It is commonly abbreviated as CIK.",
        "label": "Entity Central Index Key"
       }
      }
     },
     "localname": "EntityCentralIndexKey",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "centralIndexKeyItemType"
    },
    "dei_EntityCommonStockSharesOutstanding": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Indicate number of shares or other units outstanding of each of registrant's classes of capital or common stock or other ownership interests, if and as stated on cover of related periodic report. Where multiple classes or units exist define each class/interest by adding class of stock items such as Common Class A [Member], Common Class B [Member] or Partnership Interest [Member] onto the Instrument [Domain] of the Entity Listings, Instrument.",
        "label": "Entity Common Stock, Shares Outstanding"
       }
      }
     },
     "localname": "EntityCommonStockSharesOutstanding",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "sharesItemType"
    },
    "dei_EntityCurrentReportingStatus": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Indicate 'Yes' or 'No' whether registrants (1) have filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that registrants were required to file such reports), and (2) have been subject to such filing requirements for the past 90 days. This information should be based on the registrant's current or most recent filing containing the related disclosure.",
        "label": "Entity Current Reporting Status"
       }
      }
     },
     "localname": "EntityCurrentReportingStatus",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "yesNoItemType"
    },
    "dei_EntityEmergingGrowthCompany": {
     "auth_ref": [
      "r2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Indicate if registrant meets the emerging growth company criteria.",
        "label": "Entity Emerging Growth Company"
       }
      }
     },
     "localname": "EntityEmergingGrowthCompany",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_EntityExTransitionPeriod": {
     "auth_ref": [
      "r19"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Indicate if an emerging growth company has elected not to use the extended transition period for complying with any new or revised financial accounting standards.",
        "label": "Elected Not To Use the Extended Transition Period"
       }
      }
     },
     "localname": "EntityExTransitionPeriod",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_EntityFileNumber": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Commission file number. The field allows up to 17 characters. The prefix may contain 1-3 digits, the sequence number may contain 1-8 digits, the optional suffix may contain 1-4 characters, and the fields are separated with a hyphen.",
        "label": "Entity File Number"
       }
      }
     },
     "localname": "EntityFileNumber",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "fileNumberItemType"
    },
    "dei_EntityFilerCategory": {
     "auth_ref": [
      "r2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Indicate whether the registrant is one of the following: Large Accelerated Filer, Accelerated Filer, Non-accelerated Filer. Definitions of these categories are stated in Rule 12b-2 of the Exchange Act. This information should be based on the registrant's current or most recent filing containing the related disclosure.",
        "label": "Entity Filer Category"
       }
      }
     },
     "localname": "EntityFilerCategory",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "filerCategoryItemType"
    },
    "dei_EntityIncorporationStateCountryCode": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Two-character EDGAR code representing the state or country of incorporation.",
        "label": "Entity Incorporation, State or Country Code"
       }
      }
     },
     "localname": "EntityIncorporationStateCountryCode",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "edgarStateCountryItemType"
    },
    "dei_EntityInteractiveDataCurrent": {
     "auth_ref": [
      "r16"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true when the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for such shorter period that the registrant was required to submit such files).",
        "label": "Entity Interactive Data Current"
       }
      }
     },
     "localname": "EntityInteractiveDataCurrent",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "yesNoItemType"
    },
    "dei_EntityPrimarySicNumber": {
     "auth_ref": [
      "r14"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Primary Standard Industrial Classification (SIC) Number for the Entity.",
        "label": "Entity Primary SIC Number"
       }
      }
     },
     "localname": "EntityPrimarySicNumber",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "sicNumberItemType"
    },
    "dei_EntityPublicFloat": {
     "auth_ref": [],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The aggregate market value of the voting and non-voting common equity held by non-affiliates computed by reference to the price at which the common equity was last sold, or the average bid and asked price of such common equity, as of the last business day of the registrant's most recently completed second fiscal quarter.",
        "label": "Entity Public Float"
       }
      }
     },
     "localname": "EntityPublicFloat",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "monetaryItemType"
    },
    "dei_EntityRegistrantName": {
     "auth_ref": [
      "r2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The exact name of the entity filing the report as specified in its charter, which is required by forms filed with the SEC.",
        "label": "Entity Registrant Name"
       }
      }
     },
     "localname": "EntityRegistrantName",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_EntityShellCompany": {
     "auth_ref": [
      "r2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true when the registrant is a shell company as defined in Rule 12b-2 of the Exchange Act.",
        "label": "Entity Shell Company"
       }
      }
     },
     "localname": "EntityShellCompany",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_EntitySmallBusiness": {
     "auth_ref": [
      "r2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Indicates that the company is a Smaller Reporting Company (SRC).",
        "label": "Entity Small Business"
       }
      }
     },
     "localname": "EntitySmallBusiness",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_EntityTaxIdentificationNumber": {
     "auth_ref": [
      "r2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The Tax Identification Number (TIN), also known as an Employer Identification Number (EIN), is a unique 9-digit value assigned by the IRS.",
        "label": "Entity Tax Identification Number"
       }
      }
     },
     "localname": "EntityTaxIdentificationNumber",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "employerIdItemType"
    },
    "dei_EntityVoluntaryFilers": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Indicate 'Yes' or 'No' if the registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the Act.",
        "label": "Entity Voluntary Filers"
       }
      }
     },
     "localname": "EntityVoluntaryFilers",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "yesNoItemType"
    },
    "dei_EntityWellKnownSeasonedIssuer": {
     "auth_ref": [
      "r17"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Indicate 'Yes' or 'No' if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act. Is used on Form Type: 10-K, 10-Q, 8-K, 20-F, 6-K, 10-K/A, 10-Q/A, 20-F/A, 6-K/A, N-CSR, N-Q, N-1A.",
        "label": "Entity Well-known Seasoned Issuer"
       }
      }
     },
     "localname": "EntityWellKnownSeasonedIssuer",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "yesNoItemType"
    },
    "dei_Extension": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Extension number for local phone number.",
        "label": "Extension"
       }
      }
     },
     "localname": "Extension",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_LocalPhoneNumber": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Local phone number for entity.",
        "label": "Local Phone Number"
       }
      }
     },
     "localname": "LocalPhoneNumber",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_NoTradingSymbolFlag": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true only for a security having no trading symbol.",
        "label": "No Trading Symbol Flag"
       }
      }
     },
     "localname": "NoTradingSymbolFlag",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "trueItemType"
    },
    "dei_OtherReportingStandardItemNumber": {
     "auth_ref": [
      "r13"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "\"Item 17\" or \"Item 18\" specified when the basis of accounting is neither US GAAP nor IFRS.",
        "label": "Other Reporting Standard Item Number"
       }
      }
     },
     "localname": "OtherReportingStandardItemNumber",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "otherReportingStandardItemNumberItemType"
    },
    "dei_PreCommencementIssuerTenderOffer": {
     "auth_ref": [
      "r7"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act.",
        "label": "Pre-commencement Issuer Tender Offer"
       }
      }
     },
     "localname": "PreCommencementIssuerTenderOffer",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_PreCommencementTenderOffer": {
     "auth_ref": [
      "r8"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act.",
        "label": "Pre-commencement Tender Offer"
       }
      }
     },
     "localname": "PreCommencementTenderOffer",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_Security12bTitle": {
     "auth_ref": [
      "r1"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Title of a 12(b) registered security.",
        "label": "Title of 12(b) Security"
       }
      }
     },
     "localname": "Security12bTitle",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "securityTitleItemType"
    },
    "dei_Security12gTitle": {
     "auth_ref": [
      "r5"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Title of a 12(g) registered security.",
        "label": "Title of 12(g) Security"
       }
      }
     },
     "localname": "Security12gTitle",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "securityTitleItemType"
    },
    "dei_SecurityExchangeName": {
     "auth_ref": [
      "r4"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Name of the Exchange on which a security is registered.",
        "label": "Security Exchange Name"
       }
      }
     },
     "localname": "SecurityExchangeName",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "edgarExchangeCodeItemType"
    },
    "dei_SecurityReportingObligation": {
     "auth_ref": [
      "r9"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "15(d), indicating whether the security has a reporting obligation under that section of the Exchange Act.",
        "label": "Security Reporting Obligation"
       }
      }
     },
     "localname": "SecurityReportingObligation",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "securityReportingObligationItemType"
    },
    "dei_SolicitingMaterial": {
     "auth_ref": [
      "r10"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as soliciting material pursuant to Rule 14a-12 under the Exchange Act.",
        "label": "Soliciting Material"
       }
      }
     },
     "localname": "SolicitingMaterial",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_TradingSymbol": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Trading symbol of an instrument as listed on an exchange.",
        "label": "Trading Symbol"
       }
      }
     },
     "localname": "TradingSymbol",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "tradingSymbolItemType"
    },
    "dei_WrittenCommunications": {
     "auth_ref": [
      "r18"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as written communications pursuant to Rule 425 under the Securities Act.",
        "label": "Written Communications"
       }
      }
     },
     "localname": "WrittenCommunications",
     "nsuri": "http://xbrl.sec.gov/dei/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "booleanItemType"
    },
    "us-gaap_ClassOfStockDomain": {
     "auth_ref": [],
     "localname": "ClassOfStockDomain",
     "nsuri": "http://fasb.org/us-gaap/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_StatementClassOfStockAxis": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Class of Stock [Axis]"
       }
      }
     },
     "localname": "StatementClassOfStockAxis",
     "nsuri": "http://fasb.org/us-gaap/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_StatementLineItems": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Statement [Line Items]"
       }
      }
     },
     "localname": "StatementLineItems",
     "nsuri": "http://fasb.org/us-gaap/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_StatementTable": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Statement [Table]"
       }
      }
     },
     "localname": "StatementTable",
     "nsuri": "http://fasb.org/us-gaap/2022",
     "presentation": [
      "http://lixte.com/role/Cover"
     ],
     "xbrltype": "stringItemType"
    }
   },
   "unitCount": 3
  }
 },
 "std_ref": {
  "r0": {
   "Name": "Exchange Act",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "12"
  },
  "r1": {
   "Name": "Exchange Act",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "12",
   "Subsection": "b"
  },
  "r10": {
   "Name": "Exchange Act",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "14a",
   "Subsection": "12"
  },
  "r11": {
   "Name": "Form 10-K",
   "Number": "249",
   "Publisher": "SEC",
   "Section": "310"
  },
  "r12": {
   "Name": "Form 10-Q",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "308",
   "Subsection": "a"
  },
  "r13": {
   "Name": "Form 20-F",
   "Number": "249",
   "Publisher": "SEC",
   "Section": "220",
   "Subsection": "f"
  },
  "r14": {
   "Name": "Form 40-F",
   "Number": "249",
   "Publisher": "SEC",
   "Section": "240",
   "Subsection": "f"
  },
  "r15": {
   "Name": "Forms 10-K, 10-Q, 20-F",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "13",
   "Subsection": "a-1"
  },
  "r16": {
   "Name": "Regulation S-T",
   "Number": "232",
   "Publisher": "SEC",
   "Section": "405"
  },
  "r17": {
   "Name": "Securities Act",
   "Number": "230",
   "Publisher": "SEC",
   "Section": "405"
  },
  "r18": {
   "Name": "Securities Act",
   "Number": "230",
   "Publisher": "SEC",
   "Section": "425"
  },
  "r19": {
   "Name": "Securities Act",
   "Number": "7A",
   "Publisher": "SEC",
   "Section": "B",
   "Subsection": "2"
  },
  "r2": {
   "Name": "Exchange Act",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "12",
   "Subsection": "b-2"
  },
  "r3": {
   "Name": "Exchange Act",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "12",
   "Subsection": "b-23"
  },
  "r4": {
   "Name": "Exchange Act",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "12",
   "Subsection": "d1-1"
  },
  "r5": {
   "Name": "Exchange Act",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "12",
   "Subsection": "g"
  },
  "r6": {
   "Name": "Exchange Act",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "12, 13, 15d"
  },
  "r7": {
   "Name": "Exchange Act",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "13e",
   "Subsection": "4c"
  },
  "r8": {
   "Name": "Exchange Act",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "14d",
   "Subsection": "2b"
  },
  "r9": {
   "Name": "Exchange Act",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "15",
   "Subsection": "d"
  }
 },
 "version": "2.1"
}
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>ZIP
<SEQUENCE>17
<FILENAME>0001493152-22-028641-xbrl.zip
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
begin 644 0001493152-22-028641-xbrl.zip
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MFYF,ID&Y8S()N 69]GFWSR9%?MJ WC1LI730(;;FA<T-K ];_%2[E65Y2Y:
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MZ@&Y*CPR"'%.O$$%E(OM-[;(S0;B(,#1RV8*O$UDI%\8&15>G62(M5EU/SB
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MI4=7]EC93><-UTO,H>QQL]E*O:C\_Z)$@>EO&$/9XR:X%5H/3+Z;*K7E3'#
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M$   ESP   H              ( !     &5X.3DM,2YH=&U02P$"% ,4
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2      8 !@!Y 0  6D4

end
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
