    <SEC-DOCUMENT>0001493152-24-048292-index.html : 20241202
    <SEC-HEADER>0001493152-24-048292.hdr.sgml : 20241202
    <ACCEPTANCE-DATETIME>20241202160526
    ACCESSION NUMBER:		0001493152-24-048292
    CONFORMED SUBMISSION TYPE:	8-K
    PUBLIC DOCUMENT COUNT:		20
    CONFORMED PERIOD OF REPORT:	20241129
    ITEM INFORMATION:		Entry into a Material Definitive Agreement
    ITEM INFORMATION:		Financial Statements and Exhibits
    FILED AS OF DATE:		20241202
    DATE AS OF CHANGE:		20241202

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			LIXTE BIOTECHNOLOGY HOLDINGS, INC.
    		CENTRAL INDEX KEY:			0001335105
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		IRS NUMBER:				202903526
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		8-K
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-39717
    		FILM NUMBER:		241519011

    	BUSINESS ADDRESS:
    		STREET 1:		248 ROUTE 25A
    		STREET 2:		NO. 2
    		CITY:			EAST SETAUKET
    		STATE:			NY
    		ZIP:			11733
    		BUSINESS PHONE:		310 203 2902

    	MAIL ADDRESS:
    		STREET 1:		248 ROUTE 25A
    		STREET 2:		NO. 2
    		CITY:			EAST SETAUKET
    		STATE:			NY
    		ZIP:			11733

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	SRKP 7 INC
    		DATE OF NAME CHANGE:	20050803
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>8-K
    <SEQUENCE>1
    <FILENAME>form8-k.htm
    <TEXT>
    Document 1 - file: form8-k.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.1
    <SEQUENCE>2
    <FILENAME>ex10-1.htm
    <TEXT>
    Document 2 - file: ex10-1.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>ex10-1_001.jpg
    <TEXT>
    Document 3 - file: ex10-1_001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>ex10-1_002.jpg
    <TEXT>
    Document 4 - file: ex10-1_002.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>ex10-1_003.jpg
    <TEXT>
    Document 5 - file: ex10-1_003.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>ex10-1_004.jpg
    <TEXT>
    Document 6 - file: ex10-1_004.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>ex10-1_005.jpg
    <TEXT>
    Document 7 - file: ex10-1_005.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-101.SCH
    <SEQUENCE>8
    <FILENAME>lixt-20241129.xsd
    <DESCRIPTION>XBRL SCHEMA FILE
    <TEXT>
    Document 8 - file: lixt-20241129.xsd

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-101.DEF
    <SEQUENCE>9
    <FILENAME>lixt-20241129_def.xml
    <DESCRIPTION>XBRL DEFINITION FILE
    <TEXT>
    Document 9 - file: lixt-20241129_def.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-101.LAB
    <SEQUENCE>10
    <FILENAME>lixt-20241129_lab.xml
    <DESCRIPTION>XBRL LABEL FILE
    <TEXT>
    Document 10 - file: lixt-20241129_lab.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-101.PRE
    <SEQUENCE>11
    <FILENAME>lixt-20241129_pre.xml
    <DESCRIPTION>XBRL PRESENTATION FILE
    <TEXT>
    Document 11 - file: lixt-20241129_pre.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>13
    <FILENAME>R1.htm
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 13 - file: R1.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EXCEL
    <SEQUENCE>14
    <FILENAME>Financial_Report.xlsx
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 14 - file: Financial_Report.xlsx

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>15
    <FILENAME>Show.js
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 15 - file: Show.js

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>16
    <FILENAME>report.css
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 16 - file: report.css

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>18
    <FILENAME>FilingSummary.xml
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 18 - file: FilingSummary.html

    Document 18 - RAW XML: FilingSummary.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>JSON
    <SEQUENCE>21
    <FILENAME>MetaLinks.json
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 21 - file: MetaLinks.json

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>ZIP
    <SEQUENCE>22
    <FILENAME>0001493152-24-048292-xbrl.zip
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 22 - file: 0001493152-24-048292-xbrl.zip

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>23
    <FILENAME>form8-k_htm.xml
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 23 - file: form8-k_htm.html

    Document 23 - RAW XML: form8-k_htm.xml

    </DOCUMENT>
    </SEC-DOCUMENT>