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Summary of Stock Option Activity Including Options Form of Warrants (Details) - $ / shares
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Share-Based Payment Arrangement [Abstract]    
Number of shares, stock options outstanding, at the end 552,083 389,479
Weighted average exercise price, stock options outstanding, at the end $ 15.330 $ 29.183
Number of shares, granted 92,815 290,000
Weighted average exercise price, granted $ 2.259 $ 2.492
Number of shares, exercised (1,250)
Weighted average exercise price, exercised $ 5.025
Number of shares, expired (31,666) (126,146)
Weighted average exercise price, expired $ 35.368 $ 28.687
Number of shares, stock options outstanding, at the end 613,232 552,083
Weighted average exercise price, stock options outstanding, at the end $ 12.317 $ 15.330
Weighted average remaining contractual life (in years), stock options outstanding 3 years 29 days  
Number of shares, stock options exercisable 409,897 252,292
Weighted average exercise price, stock options exercisable $ 17.100 $ 28.387
Weighted average remaining contractual life (in years), stock options exercisable 2 years 9 months