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Pay vs Performance Disclosure - USD ($)
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Pay vs Performance Disclosure [Table]      
Pay vs Performance [Table Text Block]
Year 

Summary

Compensation

Table Total for PEO

(1)

  

Compensation

Actually Paid

to PEO

(2)

  

Average

Summary

Compensation

Table Total

for Non-PEO

NEO’s

(3)

  

Average

Compensation

Actually Paid

to Non-PEO

NEO’s

(2)

  

Value of Initial Fixed $100

Investment

Based On Total

Shareholder

Return

(4)

  

Net

Income

(Loss)

(5)

 
                         
2024  $153,495   $94,461   $562,383   $542,516   $17.06   $(3,585,965)
2023  $634,565   $669,196   $550,000   $453,624   $19.75   $(5,087,029)
2022  $315,640   $315,528   $725,739   $647,694   $42.86   $(6,312,535)
   
Named Executive Officers, Footnote [Text Block]

 

  (1) The amounts presented reflect the total compensation set forth in the Summary Compensation Table (“SCT”) for the Company’s former CEO, Dr. John S. Kovach, and the successor CEO, Bas van der Baan, who were the Company’s PEO’s during the years ended December 31, 2024, 2023 and 2022. Dr. Kovach terminated the position of CEO, and Mr. Baan was appointed the successor on September 26, 2023. Mr. Baan terminated the position of CEO, and Geordan Pursglove was appointed his successor effective June 16, 2025.
   
PEO SCT Amounts [1] $ 153,495 $ 634,565 $ 315,640
CAP Amounts, PEO [2] $ 94,461 669,196 315,528
Adjustment To PEO Compensation, Footnote [Text Block]

 

                         
   2024   2023   2022 
   PEO’s  

Other

NEO’s

   PEO  

Other

NEO’s

   PEO  

Other

NEO’s

 
                         
SCT Amounts  $153,495   $562,383   $634,565   $550,000   $315,640   $725,739 
Adjustments Related to Defined Benefit and Actuarial Plans:                              
None (6)                        
Adjustments Related to Stock-Based Compensation:                              
Values reported in Stock Awards and Option Awards columns of the SCT       (29,074)   (403,066)       (65,640)   (196,920)
Year-end fair value of awards granted during the year that are outstanding and unvested at the end of the year       19,550    434,409        49,118    147,353 
Decrease in fair value of awards granted in prior years that are outstanding and unvested at year-end   (58,757)   (2,261)       (72,405)       (39,224)
Fair value of awards granted and vested during the year       3,796    39,491        16,410    49,230 
Decrease in fair value of awards granted in prior years that vested during the year   (277)   (5,095)       (23,971)       (38,484)
Decrease in fair value of awards granted in prior years that failed to meet vesting conditions during the year       (6,783)   (36,203)            
Dividends and other earnings paid on awards before the vesting date                        
CAP Amounts  $94,461   $542,516   $669,196   $453,624   $315,528   $647,694 

 

 

  (3) The amounts presented reflect the total compensation set forth in the SCT for the Company’s Non-PEO NEOs, James S. Miser, Robert N. Weingarten, Eric J. Forman and Jan H.M. Schellens, during the periods presented.
     
  (4) The amounts presented reflect the value of a fixed investment of $100 on January 1st of the reporting period (i.e., January 1, 2022) based upon the closing market price of the Company’s common stock of $2.03, $2.35 and $5.10 at December 31, 2024, December 31, 2023 and December 31, 2022, respectively, as traded on The Nasdaq Capital Market. All amounts presented herein have been retroactively adjusted to reflect the 1-for-10 reverse split of the Company’s common stock effective June 2, 2023.
     
  (5) The amounts presented reflect the net loss as reported in the Company’s audited financial statements for the periods presented.
     
  (6) The Company had no Defined Benefit or Actuarial Plans during the periods presented.
   
NEO SCT Amounts [3] $ 562,383 550,000 725,739
CAP Amounts, OTHER NEO [2] 542,516 453,624 647,694
Total Shareholder Return Amount [4] 17.06 19.75 42.86
Net Income (Loss) Attributable to Parent [5] $ (3,585,965) $ (5,087,029) $ (6,312,535)
Additional 402(v) Disclosure [Text Block]
  (2) The following table reflects the adjustments necessary, each of which is prescribed by SEC rule, to calculate the Compensation Actually Paid (“CAP”) from those total amounts reflected in the SCT. The SCT amounts and the CAP amounts do not reflect the actual amount of compensation earned by or paid to the Company’s executives during the applicable years, but rather are amounts determined in accordance with Item 402 of Regulation S-K under the Exchange Act. To determine CAP, the adjustments below were made to the Company’s executive officer’s total compensation.
   
Dr. John S. Kovach [Member]      
Pay vs Performance Disclosure [Table]      
PEO Name Dr. John S. Kovach Dr. John S. Kovach Dr. John S. Kovach
Bas van der Baan [Member]      
Pay vs Performance Disclosure [Table]      
PEO Name Bas van der Baan Bas van der Baan Bas van der Baan
PEO [Member] | Adjustments Related to Defined Benefit and Actuarial Plans: None [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount [6]
PEO [Member] | Values Reported in Stock Awards and Option Awards Columns of SCT [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount (403,066) (65,640)
PEO [Member] | Year-End Fair Value of Awards Granted During Year are Outstanding and Unvested End of the Year [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount 434,409 49,118
PEO [Member] | Decrease in Fair Value of Awards Granted in Prior Years are Outstanding and Unvested at Year-End [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount (58,757)
PEO [Member] | Fair Value of Awards Granted and Vested During Year [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount 39,491 16,410
PEO [Member] | Decrease in Fair Value of Awards Granted in Prior Years Vested During Year [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount (277)
PEO [Member] | Decrease in Fair Value of Awards Granted in Prior Years Failed to Meet Vesting Conditions During Year [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount (36,203)
PEO [Member] | Dividends and Other Earnings Paid on Awards Before Vesting Date [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount
Non-PEO NEO [Member] | Adjustments Related to Defined Benefit and Actuarial Plans: None [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount [6]
Non-PEO NEO [Member] | Values Reported in Stock Awards and Option Awards Columns of SCT [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount (29,074) (196,920)
Non-PEO NEO [Member] | Year-End Fair Value of Awards Granted During Year are Outstanding and Unvested End of the Year [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount 19,550 147,353
Non-PEO NEO [Member] | Decrease in Fair Value of Awards Granted in Prior Years are Outstanding and Unvested at Year-End [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount (2,261) (72,405) (39,224)
Non-PEO NEO [Member] | Fair Value of Awards Granted and Vested During Year [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount 3,796 49,230
Non-PEO NEO [Member] | Decrease in Fair Value of Awards Granted in Prior Years Vested During Year [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount (5,095) (23,971) (38,484)
Non-PEO NEO [Member] | Decrease in Fair Value of Awards Granted in Prior Years Failed to Meet Vesting Conditions During Year [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount (6,783)
Non-PEO NEO [Member] | Dividends and Other Earnings Paid on Awards Before Vesting Date [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount
[1] The amounts presented reflect the total compensation set forth in the Summary Compensation Table (“SCT”) for the Company’s former CEO, Dr. John S. Kovach, and the successor CEO, Bas van der Baan, who were the Company’s PEO’s during the years ended December 31, 2024, 2023 and 2022. Dr. Kovach terminated the position of CEO, and Mr. Baan was appointed the successor on September 26, 2023. Mr. Baan terminated the position of CEO, and Geordan Pursglove was appointed his successor effective June 16, 2025.
[2] The following table reflects the adjustments necessary, each of which is prescribed by SEC rule, to calculate the Compensation Actually Paid (“CAP”) from those total amounts reflected in the SCT. The SCT amounts and the CAP amounts do not reflect the actual amount of compensation earned by or paid to the Company’s executives during the applicable years, but rather are amounts determined in accordance with Item 402 of Regulation S-K under the Exchange Act. To determine CAP, the adjustments below were made to the Company’s executive officer’s total compensation.
[3] The amounts presented reflect the total compensation set forth in the SCT for the Company’s Non-PEO NEOs, James S. Miser, Robert N. Weingarten, Eric J. Forman and Jan H.M. Schellens, during the periods presented.
[4] The amounts presented reflect the value of a fixed investment of $100 on January 1st of the reporting period (i.e., January 1, 2022) based upon the closing market price of the Company’s common stock of $2.03, $2.35 and $5.10 at December 31, 2024, December 31, 2023 and December 31, 2022, respectively, as traded on The Nasdaq Capital Market. All amounts presented herein have been retroactively adjusted to reflect the 1-for-10 reverse split of the Company’s common stock effective June 2, 2023.
[5] The amounts presented reflect the net loss as reported in the Company’s audited financial statements for the periods presented.
[6] The Company had no Defined Benefit or Actuarial Plans during the periods presented.