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Cover
Dec. 17, 2025
Cover [Abstract]  
Document Type 8-K
Amendment Flag false
Document Period End Date Dec. 17, 2025
Entity File Number 001-39717
Entity Registrant Name LIXTE BIOTECHNOLOGY HOLDINGS, INC.
Entity Central Index Key 0001335105
Entity Tax Identification Number 20-2903526
Entity Incorporation, State or Country Code DE
Entity Address, Address Line One 433 Plaza Real
Entity Address, Address Line Two Suite 275
Entity Address, City or Town Boca Raton
Entity Address, State or Province FL
Entity Address, Postal Zip Code 33432
City Area Code (631)
Local Phone Number 830-7092
Written Communications false
Soliciting Material false
Pre-commencement Tender Offer false
Pre-commencement Issuer Tender Offer false
Title of 12(b) Security Common Stock, par value $0.0001 per share
Trading Symbol LIXT
Security Exchange Name NASDAQ
Entity Emerging Growth Company false