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Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2024 | Jun. 30, 2023
Cash Flows Used in Operating Activities: |  |
Net loss | $ (35,265) | $ (35,948)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 69 | 77
Net accretion of discounts/premiums on debt securities | (955) | (1,729)
Stock-based compensation | 4,003 | 5,737
Loss on investment in joint venture | 1,172 | 780
Changes in operating assets and liabilities: |  |
Prepaid expenses, right-of-use assets and other assets | 2,134 | 1,595
Accounts payable | 242 | (387)
Accrued expenses and operating lease liabilities | 1,328 | (2,274)
Deferred revenue | 1,397 | 0
Net cash used in operating activities | (25,875) | (32,149)
Cash Flows Provided By (Used In) Investing Activities: |  |
Purchases of marketable securities | (29,890) | (61,603)
Proceeds from maturities of marketable securities | 44,250 | 70,032
Investment in joint venture | (1,500) | (750)
Net cash provided by investing activities | 12,860 | 7,679
Cash Flows Provided By (Used In) Financing Activities: |  |
Proceeds from the issuance of common stock from a securities purchase agreement | 5,405 | 0
Proceeds from the issuance of common stock under the stock purchase plan | 44 | 209
Payments of offering costs | (257) | (138)
Net cash provided by financing activities | 5,192 | 71
Net decrease in cash and cash equivalents | (7,823) | (24,399)
Cash and cash equivalents — beginning of period | 24,494 | 56,958
Cash and cash equivalents — end of period | 16,671 | 32,559
Supplemental Disclosures of Noncash Financing Activities: |  |
Offering costs in accrued expenses | $ 11 | $ 0

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