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Note 5 - Property, Plant and Equipment - Major Classes of Property, Plant and Equipment (Details) - USD ($) | 12 Months Ended
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Dec. 31, 2016 | Dec. 31, 2015
Property, plant and equipment, gross |  | $ 20,206,400 | $ 20,310,944
Less: Accumulated depreciation and amortization |  | (5,861,476) | (5,517,021)
Property, plant and equipment, net |  | 14,344,924 | 14,793,923
Depreciation and amortization expense (1) | [1] | 813,657 | 826,529
Land [Member] |  |  |
Property, plant and equipment, gross |  | 2,220,000 | 2,220,000
Building [Member] |  |  |
Property, plant and equipment, gross |  | 6,631,039 | 6,631,039
Building Improvements [Member] |  |  |
Property, plant and equipment, gross |  | 5,615,823 | 5,615,823
Machinery and Equipment [Member] |  |  |
Property, plant and equipment, gross |  | 2,671,333 | 2,381,964
Furniture and Fixtures [Member] |  |  |
Property, plant and equipment, gross |  | 547,144 | 721,919
Computer Equipment [Member] |  |  |
Property, plant and equipment, gross |  | 479,534 | 701,367
Transportation Equipment [Member] |  |  |
Property, plant and equipment, gross |  | 65,994 | 65,994
Lab Equipment [Member] |  |  |
Property, plant and equipment, gross |  | $ 1,975,533 | $ 1,972,838
[1] | Includes amortization expense of $31,356 and $24,759 for the years ending December 31, 2016 and 2015, respectively. Such amortization expense relates to other capitalized and intangible assets.

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- Definition Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.14) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 + Details
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