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Note 10 - Income Taxes - Effective Income Tax Rate Reconciliation (Details) - USD ($)	12 Months Ended
	Dec. 31, 2017	Dec. 31, 2016
Expected provision at federal statutory tax rate (34%)	$ 2,740,010	$ (222,083)
State taxes, net of federal benefit	11,580	2,504
Stock-based compensation expense	(161,429)	(269,163)
Net operating loss carryforward	7,280	(21,412)
Federal research & development credit	(781,760)	(144,522)
Other permanent differences	118,263	150,615
Income tax (benefit)/expense	$ 1,933,944	$ (504,061)

X

- Definition

Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

+ References

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Amount of difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying domestic federal statutory income tax rates to pretax income (loss) from continuing operations, attributable to disposition of asset. Includes, but is not limited to, intra-entity transfer of asset other than inventory.

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