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Note 9 - Income Taxes - Effective Income Tax Rate Reconciliation (Details) - USD ($) | 12 Months Ended
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Dec. 31, 2019 | Dec. 31, 2018
Expected provision at federal statutory tax rate (21%) | $ (1,031,888) | $ (1,167,092)
Provision for valuation allowance | 2,497,414 |
Foreign tax loss | 57,856 | 99,215
Adjustment to 2017 tax return |  | 58,304
State taxes, net of federal benefit | (11,506) | 80,367
Stock-based compensation expense |  | 185,675
Federal research & development credit | (174,416) | (83,245)
Other permanent differences | 76,448 | 470,214
Income tax expense/(benefit) | $ 1,413,908 | $ (356,562)

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