    <SEC-DOCUMENT>0001104659-22-009095-index.html : 20220622
    <SEC-HEADER>0001104659-22-009095.hdr.sgml : 20220622
    <ACCEPTANCE-DATETIME>20220128172406
    <PRIVATE-TO-PUBLIC>
    ACCESSION NUMBER:		0001104659-22-009095
    CONFORMED SUBMISSION TYPE:	DRS
    PUBLIC DOCUMENT COUNT:		89
    FILED AS OF DATE:		20220128
    <PUBLIC-REL-DATE>20220622
    DATE AS OF CHANGE:		20220131

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			ProMIS Neurosciences Inc.
    		CENTRAL INDEX KEY:			0001374339
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			Z4
    		FISCAL YEAR END:			0331

    	FILING VALUES:
    		FORM TYPE:		DRS
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	377-05970
    		FILM NUMBER:		22570197

    	BUSINESS ADDRESS:
    		STREET 1:		SUITE 200, 1920 YONGE STREET
    		CITY:			TORONTO
    		STATE:			A6
    		ZIP:			M4S 3E2
    		BUSINESS PHONE:		416-847-6898

    	MAIL ADDRESS:
    		STREET 1:		SUITE 200, 1920 YONGE STREET
    		CITY:			TORONTO
    		STATE:			A6
    		ZIP:			M4S 3E2

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	AMORFIX LIFE SCIENCES LTD
    		DATE OF NAME CHANGE:	20060831
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DRS
    <SEQUENCE>1
    <FILENAME>filename1.htm
    <TEXT>
    Document 1 - file: filename1.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-3.1
    <SEQUENCE>2
    <FILENAME>filename2.htm
    <TEXT>
    Document 2 - file: filename2.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-3.1(1)
    <SEQUENCE>3
    <FILENAME>filename3.htm
    <TEXT>
    Document 3 - file: filename3.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-3.2
    <SEQUENCE>4
    <FILENAME>filename4.htm
    <TEXT>
    Document 4 - file: filename4.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-3.2(1)
    <SEQUENCE>5
    <FILENAME>filename5.htm
    <TEXT>
    Document 5 - file: filename5.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-4.1
    <SEQUENCE>6
    <FILENAME>filename6.htm
    <TEXT>
    Document 6 - file: filename6.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-4.2
    <SEQUENCE>7
    <FILENAME>filename7.htm
    <TEXT>
    Document 7 - file: filename7.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.1
    <SEQUENCE>8
    <FILENAME>filename8.htm
    <TEXT>
    Document 8 - file: filename8.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.2
    <SEQUENCE>9
    <FILENAME>filename9.htm
    <TEXT>
    Document 9 - file: filename9.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.3
    <SEQUENCE>10
    <FILENAME>filename10.htm
    <TEXT>
    Document 10 - file: filename10.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.3(1)
    <SEQUENCE>11
    <FILENAME>filename11.htm
    <TEXT>
    Document 11 - file: filename11.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.3(2)
    <SEQUENCE>12
    <FILENAME>filename12.htm
    <TEXT>
    Document 12 - file: filename12.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.3(3)
    <SEQUENCE>13
    <FILENAME>filename13.htm
    <TEXT>
    Document 13 - file: filename13.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.3(4)
    <SEQUENCE>14
    <FILENAME>filename14.htm
    <TEXT>
    Document 14 - file: filename14.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.4
    <SEQUENCE>15
    <FILENAME>filename15.htm
    <TEXT>
    Document 15 - file: filename15.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.5
    <SEQUENCE>16
    <FILENAME>filename16.htm
    <TEXT>
    Document 16 - file: filename16.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.6
    <SEQUENCE>17
    <FILENAME>filename17.htm
    <TEXT>
    Document 17 - file: filename17.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.7
    <SEQUENCE>18
    <FILENAME>filename18.htm
    <TEXT>
    Document 18 - file: filename18.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.7(1)
    <SEQUENCE>19
    <FILENAME>filename19.htm
    <TEXT>
    Document 19 - file: filename19.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.7(2)
    <SEQUENCE>20
    <FILENAME>filename20.htm
    <TEXT>
    Document 20 - file: filename20.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.7(3)
    <SEQUENCE>21
    <FILENAME>filename21.htm
    <TEXT>
    Document 21 - file: filename21.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.8
    <SEQUENCE>22
    <FILENAME>filename22.htm
    <TEXT>
    Document 22 - file: filename22.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.9
    <SEQUENCE>23
    <FILENAME>filename23.htm
    <TEXT>
    Document 23 - file: filename23.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.10
    <SEQUENCE>24
    <FILENAME>filename24.htm
    <TEXT>
    Document 24 - file: filename24.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.11
    <SEQUENCE>25
    <FILENAME>filename25.htm
    <TEXT>
    Document 25 - file: filename25.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.12
    <SEQUENCE>26
    <FILENAME>filename26.htm
    <TEXT>
    Document 26 - file: filename26.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.12(1)
    <SEQUENCE>27
    <FILENAME>filename27.htm
    <TEXT>
    Document 27 - file: filename27.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.12(2)
    <SEQUENCE>28
    <FILENAME>filename28.htm
    <TEXT>
    Document 28 - file: filename28.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.12(3)
    <SEQUENCE>29
    <FILENAME>filename29.htm
    <TEXT>
    Document 29 - file: filename29.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.12(4)
    <SEQUENCE>30
    <FILENAME>filename30.htm
    <TEXT>
    Document 30 - file: filename30.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.13
    <SEQUENCE>31
    <FILENAME>filename31.htm
    <TEXT>
    Document 31 - file: filename31.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.14
    <SEQUENCE>32
    <FILENAME>filename32.htm
    <TEXT>
    Document 32 - file: filename32.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.15
    <SEQUENCE>33
    <FILENAME>filename33.htm
    <TEXT>
    Document 33 - file: filename33.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.16
    <SEQUENCE>34
    <FILENAME>filename34.htm
    <TEXT>
    Document 34 - file: filename34.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.17
    <SEQUENCE>35
    <FILENAME>filename35.htm
    <TEXT>
    Document 35 - file: filename35.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.18
    <SEQUENCE>36
    <FILENAME>filename36.htm
    <TEXT>
    Document 36 - file: filename36.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.19
    <SEQUENCE>37
    <FILENAME>filename37.htm
    <TEXT>
    Document 37 - file: filename37.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.20
    <SEQUENCE>38
    <FILENAME>filename38.htm
    <TEXT>
    Document 38 - file: filename38.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.21
    <SEQUENCE>39
    <FILENAME>filename39.htm
    <TEXT>
    Document 39 - file: filename39.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.22
    <SEQUENCE>40
    <FILENAME>filename40.htm
    <TEXT>
    Document 40 - file: filename40.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.23
    <SEQUENCE>41
    <FILENAME>filename41.htm
    <TEXT>
    Document 41 - file: filename41.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.24
    <SEQUENCE>42
    <FILENAME>filename42.htm
    <TEXT>
    Document 42 - file: filename42.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.25
    <SEQUENCE>43
    <FILENAME>filename43.htm
    <TEXT>
    Document 43 - file: filename43.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.26
    <SEQUENCE>44
    <FILENAME>filename44.htm
    <TEXT>
    Document 44 - file: filename44.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.27
    <SEQUENCE>45
    <FILENAME>filename45.htm
    <TEXT>
    Document 45 - file: filename45.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.28
    <SEQUENCE>46
    <FILENAME>filename46.htm
    <TEXT>
    Document 46 - file: filename46.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.29
    <SEQUENCE>47
    <FILENAME>filename47.htm
    <TEXT>
    Document 47 - file: filename47.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.30
    <SEQUENCE>48
    <FILENAME>filename48.htm
    <TEXT>
    Document 48 - file: filename48.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.31
    <SEQUENCE>49
    <FILENAME>filename49.htm
    <TEXT>
    Document 49 - file: filename49.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.32
    <SEQUENCE>50
    <FILENAME>filename50.htm
    <TEXT>
    Document 50 - file: filename50.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.33
    <SEQUENCE>51
    <FILENAME>filename51.htm
    <TEXT>
    Document 51 - file: filename51.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.34
    <SEQUENCE>52
    <FILENAME>filename52.htm
    <TEXT>
    Document 52 - file: filename52.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.35
    <SEQUENCE>53
    <FILENAME>filename53.htm
    <TEXT>
    Document 53 - file: filename53.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.35(1)
    <SEQUENCE>54
    <FILENAME>filename54.htm
    <TEXT>
    Document 54 - file: filename54.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.36
    <SEQUENCE>55
    <FILENAME>filename55.htm
    <TEXT>
    Document 55 - file: filename55.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.37
    <SEQUENCE>56
    <FILENAME>filename56.htm
    <TEXT>
    Document 56 - file: filename56.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.38
    <SEQUENCE>57
    <FILENAME>filename57.htm
    <TEXT>
    Document 57 - file: filename57.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.39
    <SEQUENCE>58
    <FILENAME>filename58.htm
    <TEXT>
    Document 58 - file: filename58.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>59
    <FILENAME>tm2135630d1_drs3-12.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 59 - file: tm2135630d1_drs3-12.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>60
    <FILENAME>tm2135630d1_drs3-13.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 60 - file: tm2135630d1_drs3-13.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>61
    <FILENAME>tm2135630d1_drs3-16.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 61 - file: tm2135630d1_drs3-16.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>62
    <FILENAME>tm2135630d1_drs3-17.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 62 - file: tm2135630d1_drs3-17.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>63
    <FILENAME>tm2135630d1_drsimg0001.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 63 - file: tm2135630d1_drsimg0001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>64
    <FILENAME>tm2135630d1_drsimg1.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 64 - file: tm2135630d1_drsimg1.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>65
    <FILENAME>tm2135630d1_drsimg11.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 65 - file: tm2135630d1_drsimg11.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>66
    <FILENAME>tm2135630d1_drsimg12.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 66 - file: tm2135630d1_drsimg12.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>67
    <FILENAME>tm2135630d1_drsimg13.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 67 - file: tm2135630d1_drsimg13.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>68
    <FILENAME>tm2135630d1_drsimg14.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 68 - file: tm2135630d1_drsimg14.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>69
    <FILENAME>tm2135630d1_drsimg15.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 69 - file: tm2135630d1_drsimg15.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>70
    <FILENAME>tm2135630d1_drsimg16.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 70 - file: tm2135630d1_drsimg16.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>71
    <FILENAME>tm2135630d1_drsimg19.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 71 - file: tm2135630d1_drsimg19.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>72
    <FILENAME>tm2135630d1_drsimg2.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 72 - file: tm2135630d1_drsimg2.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>73
    <FILENAME>tm2135630d1_drsimg22.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 73 - file: tm2135630d1_drsimg22.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>74
    <FILENAME>tm2135630d1_drsimg23.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 74 - file: tm2135630d1_drsimg23.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>75
    <FILENAME>tm2135630d1_drsimg24.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 75 - file: tm2135630d1_drsimg24.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>76
    <FILENAME>tm2135630d1_drsimg3.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 76 - file: tm2135630d1_drsimg3.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>77
    <FILENAME>tm2135630d1_drsimg4.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 77 - file: tm2135630d1_drsimg4.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>78
    <FILENAME>tm2135630d1_drsimg5.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 78 - file: tm2135630d1_drsimg5.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>79
    <FILENAME>tm2135630d1_drsimg6.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 79 - file: tm2135630d1_drsimg6.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>80
    <FILENAME>tm2135630d1_drsimg8.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 80 - file: tm2135630d1_drsimg8.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>81
    <FILENAME>tm2135630d1_ex10-3d1img01.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 81 - file: tm2135630d1_ex10-3d1img01.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>82
    <FILENAME>tm2135630d1_ex10-3d1img02.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 82 - file: tm2135630d1_ex10-3d1img02.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>83
    <FILENAME>tm2135630d1_ex10-3d4img01.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 83 - file: tm2135630d1_ex10-3d4img01.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>84
    <FILENAME>tm2135630d1_ex3-1d1img01.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 84 - file: tm2135630d1_ex3-1d1img01.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>85
    <FILENAME>tm2135630d1_ex3-1d1img02.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 85 - file: tm2135630d1_ex3-1d1img02.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>86
    <FILENAME>tm2135630d1_ex3-1img01.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 86 - file: tm2135630d1_ex3-1img01.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>87
    <FILENAME>tm2135630d1_ex3-1img02.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 87 - file: tm2135630d1_ex3-1img02.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>88
    <FILENAME>tm2135630d1_ex3-1img03.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 88 - file: tm2135630d1_ex3-1img03.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>89
    <FILENAME>tm2135630d1_ex3-1img04.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 89 - file: tm2135630d1_ex3-1img04.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>