    <SEC-DOCUMENT>0001104659-23-066845-index.html : 20230601
    <SEC-HEADER>0001104659-23-066845.hdr.sgml : 20230601
    <ACCEPTANCE-DATETIME>20230601080025
    ACCESSION NUMBER:		0001104659-23-066845
    CONFORMED SUBMISSION TYPE:	DEF 14A
    PUBLIC DOCUMENT COUNT:		14
    CONFORMED PERIOD OF REPORT:	20230629
    FILED AS OF DATE:		20230601
    DATE AS OF CHANGE:		20230601

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			ProMIS Neurosciences Inc.
    		CENTRAL INDEX KEY:			0001374339
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			Z4
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DEF 14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-41429
    		FILM NUMBER:		23983029

    	BUSINESS ADDRESS:
    		STREET 1:		SUITE 200, 1920 YONGE STREET
    		CITY:			TORONTO
    		STATE:			A6
    		ZIP:			M4S 3E2
    		BUSINESS PHONE:		416-847-6898

    	MAIL ADDRESS:
    		STREET 1:		SUITE 200, 1920 YONGE STREET
    		CITY:			TORONTO
    		STATE:			A6
    		ZIP:			M4S 3E2

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	AMORFIX LIFE SCIENCES LTD
    		DATE OF NAME CHANGE:	20060831
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DEF 14A
    <SEQUENCE>1
    <FILENAME>tm2316204-5_def14a.htm
    <DESCRIPTION>DEF 14A
    <TEXT>
    Document 1 - file: tm2316204-5_def14a.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>lg_promisneuroscienctm-4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: lg_promisneuroscienctm-4clr.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>px_ontarioformpg01-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: px_ontarioformpg01-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>px_ontarioformpg02-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: px_ontarioformpg02-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>px_ontarioformpg03-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: px_ontarioformpg03-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>px_ontarioformpg04-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 6 - file: px_ontarioformpg04-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>px_ontarioformpg05-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 7 - file: px_ontarioformpg05-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>px_ontarioformpg06-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 8 - file: px_ontarioformpg06-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>px_ontarioformpg07-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 9 - file: px_ontarioformpg07-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>px_ontarioformpg08-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 10 - file: px_ontarioformpg08-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>px_ontarioformpg09-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 11 - file: px_ontarioformpg09-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>px_ontarioformpg10-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 12 - file: px_ontarioformpg10-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>px_promisneuroproxypg01-bw.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 13 - file: px_promisneuroproxypg01-bw.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>px_promisneuroproxypg02-bw.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 14 - file: px_promisneuroproxypg02-bw.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>