<SEC-DOCUMENT>0001178913-25-003546-index.html : 20251023
<SEC-HEADER>0001178913-25-003546.hdr.sgml : 20251023
<ACCEPTANCE-DATETIME>20251023060257
ACCESSION NUMBER:		0001178913-25-003546
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20251023
DATE AS OF CHANGE:		20251023

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ProMIS Neurosciences Inc.
		CENTRAL INDEX KEY:			0001374339
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				000000000
		STATE OF INCORPORATION:			Z4
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-93797
		FILM NUMBER:		251411275

	BUSINESS ADDRESS:	
		STREET 1:		SUITE 200, 1920 YONGE STREET
		CITY:			TORONTO
		STATE:			A6
		ZIP:			M4S 3E2
		BUSINESS PHONE:		416-847-6898

	MAIL ADDRESS:	
		STREET 1:		SUITE 200, 1920 YONGE STREET
		CITY:			TORONTO
		STATE:			A6
		ZIP:			M4S 3E2

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AMORFIX LIFE SCIENCES LTD
		DATE OF NAME CHANGE:	20060831

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			SPHERA FUNDS MANAGEMENT LTD.
		CENTRAL INDEX KEY:			0001496201
		ORGANIZATION NAME:           	
		EIN:				000000000
		STATE OF INCORPORATION:			L3

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		4 ITZHAK SADE BUILDING A
		STREET 2:		29TH FLOOR
		CITY:			TEL AVIV
		STATE:			L3
		ZIP:			6777520
		BUSINESS PHONE:		972-3-6845535

	MAIL ADDRESS:	
		STREET 1:		4 ITZHAK SADE BUILDING A
		STREET 2:		29TH FLOOR
		CITY:			TEL AVIV
		STATE:			L3
		ZIP:			6777520
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
Document 1 - file: primary_doc.html

Document 1 - RAW XML: primary_doc.xml

</DOCUMENT>
</SEC-DOCUMENT>