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Condensed Statements of Cash Flows - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2016 | Jun. 30, 2015
Statement of Cash Flows |  |
Net loss | $ (3,494) | $ (3,890)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Share-based compensation | 218 | 87
Non-cash interest on convertible notes to related parties | 108 | 11
Non-cash interest on convertible notes | 199 | 22
Non-cash discount amortization on convertible notes to related parties | (33) | 49
Non-cash discount amortization on convertible notes | (243) | 226
Revaluation of premium conversion derivative | (607) | 380
Non-cash acquisition of in-process research and development |  | 908
Change in assets and liabilities: |  |
Prepaid expenses and deposits | (148) |
Accounts payable | 111 | 406
Accrued liabilities | 103 | 186
Net cash used in operating activities | (3,786) | (1,615)
Financing activities |  |
Proceeds from issuance of convertible notes | 2,651 | 1,650
Proceeds from issuance of convertible notes to related parties | 2,500 | 315
Issuance costs related to convertible notes | (10) |
Proceeds from issuance of Series A convertible preferred stock |  | 1,522
Deferred offering costs | (149) |
Net cash provided by financing activities | 4,992 | 3,487
Net increase in cash and cash equivalents | 1,206 | 1,872
Cash and cash equivalents at beginning of period | 3,620 | 317
Cash and cash equivalents at end of period | 4,826 | 2,189
Supplemental disclosure of cash flow information: |  |
Cash paid for interest |  | 2
Supplemental non-cash financing transactions: |  |
Conversion of convertible notes to Series A preferred stock |  | 2,778
Exercise of premium conversion derivative |  | 685
Redemption value change of Series A preferred stock | 299 | 2,666
Issuance of common stock for acquisition of in‑process research and development |  | 908
Bifurcation of premium conversion derivative related to convertible notes | 505 | $ 232
Deferred offering costs in accounts payable and accrued liabilities | $ 734 |

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