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Commitments and Contigencies - Pfizer License Agreement (Details) - USD ($)	Dec. 31, 2016	Dec. 31, 2015
Commitments and Contingencies
No liabilities were recorded related to the license agreement	$ 4,122,000	$ 8,917,000
Pfizer, Inc. | License Agreement
Commitments and Contingencies
No liabilities were recorded related to the license agreement	$ 0

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Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.19-26)
-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

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