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Income Taxes -Significant components of deferred tax assets and liabilitie (Details) - USD ($)
$ in Thousands
Dec. 31, 2016
Dec. 31, 2015
Deferred tax assets:    
Federal and state operating loss carryforwards $ 2,289 $ 2,723
Research and development costs deferral election 5,254  
Acquired intangibles 351 345
Accruals 13  
Convertible notes   460
Charitable contributions 12 4
Stock-based compensation 633 41
Research and development credit carryforwards 768 95
Total deferred tax assets 9,320 3,668
Valuation allowance $ (9,320) (3,657)
Total deferred tax assets, net of valuation allowance   11
Deferred tax liabilities:    
Restricted stock awards   (11)
Total deferred tax liabilities   $ (11)