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Statements of Cash Flows - USD ($)
shares in Thousands, $ in Thousands
 12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Net loss $ (14,586) $ (9,029) $ (320)
Adjustments to reconcile net loss to net cash used in operating activities:      
Share-based compensation 1,718 284 53
Non-cash interest on promissory notes to related parties     19
Non-cash interest on convertible notes to related parties 145 40 5
Non-cash interest on convertible notes 256 100 1
Non-cash discount amortization on convertible notes to related parties (17) 62 7
Non-cash discount amortization on convertible notes (276) 261 5
Revaluation of premium conversion derivative (850) 297 18
Non-cash loss on extinguishment of convertible notes   198  
Non-cash interest upon conversion of convertible notes 649    
Non-cash acquisition of in-process research and development   908  
Change in assets and liabilities:      
Prepaid expenses and other assets (55) (10) 2
Accounts payable 1,477 444 (6)
Accrued and other liabilities 496 1,012 21
Net cash used in operating activities (11,043) (5,433) (195)
Financing activities      
Proceeds from issuance of convertible notes 2,651 5,560 390
Proceeds from issuance of convertible notes to related parties 2,500 1,856 25
Issuance costs related to convertible notes (10)    
Proceeds from issuance of promissory notes to related parties     94
Proceeds from issuance of Series A convertible preferred stock   1,522  
Proceeds from issuance of common stock   3  
Proceeds from offering 30,278    
Offering costs (3,963) (205)  
Net cash provided by financing activities 31,456 8,736 509
Net increase in cash and cash equivalents 20,413 3,303 314
Cash and cash equivalents at beginning of period 3,620 317 3
Cash and cash equivalents at end of period 24,033 3,620 317
Supplemental disclosure of cash flow information:      
Cash paid for interest   2  
Supplemental non-cash financing transactions:      
Exercise of premium conversion derivative   685  
Redemption value change of Series A preferred stock 366 $ 2,968  
Issuance of common stock for acquisition of in-process research and development   908  
Bifurcation of premium conversion derivative related to convertible notes 505 $ 842 55
Convertible note extinguishment   1,426  
Premium conversion derivative reduction upon convertible note extinguishment   182  
Separation of beneficial conversion feature associated with convertible notes 372    
Other Assets      
Supplemental non-cash financing transactions:      
Offering costs 205    
Accounts Payable and Accrued Liabilities      
Supplemental non-cash financing transactions:      
Offering costs   642  
Conversion of Interim Notes      
Supplemental non-cash financing transactions:      
Conversion of debt instrument to stock 11,445    
Conversion of Convertible Notes      
Supplemental non-cash financing transactions:      
Conversion of debt instrument to stock   $ 2,778  
Conversion of related party promissory notes      
Supplemental non-cash financing transactions:      
Conversion of debt instrument to stock     $ 359
Conversion of Series A Preferred Stock      
Supplemental non-cash financing transactions:      
Conversion of Series A preferred stock to common stock $ 8,319