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Commitments and Contingencies - YourChoice and Pfizer License Agreement (Details) $ in Thousands | 12 Months Ended |
--- | --- | ---
Dec. 31, 2022 USD ($) | Dec. 31, 2021 USD ($) | Dec. 31, 2020 USD ($)
Commitments and Contingencies |  |  |
Percentage of royalty payments | 2.50% |  |
Tier One Net Sales Milestone [Member] |  |  |
Commitments and Contingencies |  |  |
Sales based milestone payment | $ 1,000 |  |
Payments for specified global net sales milestones | 500,000 |  |
Tier Two Net Sales Milestone [Member] |  |  |
Commitments and Contingencies |  |  |
Sales based milestone payment | 1,500 |  |
Payments for specified global net sales milestones | 1,000,000 |  |
Tier Three Net Sales Milestone [Member] |  |  |
Commitments and Contingencies |  |  |
Sales based milestone payment | 4,000 |  |
Payments for specified global net sales milestones | 3,000,000 |  |
Tier Four Net Sales Milestone [Member] |  |  |
Commitments and Contingencies |  |  |
Sales based milestone payment | 8,000 |  |
Payments for specified global net sales milestones | 5,000,000 |  |
YourChoice | License Agreements |  |  |
Commitments and Contingencies |  |  |
Milestones or royalty payments triggered | $ 0 | $ 0 |
Royalty and milestone payment due |  |  | $ 19,500
Percentage of royalty payments | 0.50% |  |
YourChoice | License Agreements | Milestone Payments |  |  |
Commitments and Contingencies |  |  |
Royalty and milestone payment due | $ 5,000 |  |
Pfizer, Inc. | License Agreements |  |  |
Commitments and Contingencies |  |  |
Number of years after the first commercial sale | five |  |
Milestones or royalty payments triggered | $ 0 | $ 0 |
Notice period | 90 days |  |
Termination fee | $ 3,000 |  |
Pfizer, Inc. | License Agreements | Milestone Payments | Maximum |  |  |
Commitments and Contingencies |  |  |
Potential payments upon achievement of certain milestones | 37,000 |  |

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