    <SEC-DOCUMENT>0001104659-26-004337-index.html : 20260116
    <SEC-HEADER>0001104659-26-004337.hdr.sgml : 20260116
    <ACCEPTANCE-DATETIME>20260116083651
    ACCESSION NUMBER:		0001104659-26-004337
    CONFORMED SUBMISSION TYPE:	424B4
    PUBLIC DOCUMENT COUNT:		25
    FILED AS OF DATE:		20260116
    DATE AS OF CHANGE:		20260116

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			MetaVia Inc.
    		CENTRAL INDEX KEY:			0001638287
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				472389984
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		424B4
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-292581
    		FILM NUMBER:		26537724

    	BUSINESS ADDRESS:
    		STREET 1:		545 CONCORD AVENUE
    		STREET 2:		SUITE 210
    		CITY:			CAMBRIDGE
    		STATE:			MA
    		ZIP:			02138
    		BUSINESS PHONE:		(857) 702-9600

    	MAIL ADDRESS:
    		STREET 1:		545 CONCORD AVENUE
    		STREET 2:		SUITE 210
    		CITY:			CAMBRIDGE
    		STATE:			MA
    		ZIP:			02138

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	NeuroBo Pharmaceuticals, Inc.
    		DATE OF NAME CHANGE:	20191231

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Gemphire Therapeutics Inc.
    		DATE OF NAME CHANGE:	20150331
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>424B4
    <SEQUENCE>1
    <FILENAME>tm2528002-19_424b4.htm
    <DESCRIPTION>424B4
    <TEXT>
    Document 1 - file: tm2528002-19_424b4.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>lg_metavia-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: lg_metavia-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>fc_pipeline-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: fc_pipeline-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>fc_mash-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: fc_mash-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>bc_exploratoryp1b-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: bc_exploratoryp1b-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>bc_biomarker-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 6 - file: bc_biomarker-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>bc_changesbaseline-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 7 - file: bc_changesbaseline-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>bc_lsm1-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 8 - file: bc_lsm1-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>bc_lsm2-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 9 - file: bc_lsm2-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>bc_lsm3-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 10 - file: bc_lsm3-4c.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>bc_lsm4-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 11 - file: bc_lsm4-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>bc_week16-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 12 - file: bc_week16-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>bc_cfbpercentage-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 13 - file: bc_cfbpercentage-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>ph_oxyntomodulin-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 14 - file: ph_oxyntomodulin-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>lc_preclinical-4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 15 - file: lc_preclinical-4clr.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>16
    <FILENAME>bc_comparision-4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 16 - file: bc_comparision-4clr.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>17
    <FILENAME>tb_disposition-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 17 - file: tb_disposition-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>18
    <FILENAME>tb_baseline-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 18 - file: tb_baseline-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>19
    <FILENAME>tb_primarysafety-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 19 - file: tb_primarysafety-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>20
    <FILENAME>bc_exploratory-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 20 - file: bc_exploratory-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>21
    <FILENAME>bc_exploratoryweight-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 21 - file: bc_exploratoryweight-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>22
    <FILENAME>tb_exploratorywaist-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 22 - file: tb_exploratorywaist-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>23
    <FILENAME>tb_fastedglucose-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 23 - file: tb_fastedglucose-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>24
    <FILENAME>tb_vctechange-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 24 - file: tb_vctechange-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>25
    <FILENAME>tb_pkphase1-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 25 - file: tb_pkphase1-4c.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>