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Share-Based Compensation (Tables) | 12 Months Ended
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Dec. 31, 2012
Share-based Compensation [Abstract] |
Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block] | The following table summarizes the activity for stock options and warrants for the year ended December 31, 2012:
| Stock Options |  | Warrants
| Shares |  | Weighted Average Exercise Price |  | Shares |  | Weighted Average Exercise Price
Outstanding at December 31, 2010 | 13,032,214 |  |  | $1.66 |  | 21,843,507 |  |  | $2.62
Changes during the Year: |  |  |  |  |  |  |
Granted | 8,697,600 |  |  | $1.50 |  | 15,993,947 |  |  | $2.09
Exercised | (5,000 | ) |  | $1.42 |  | — |  |  | —
Forfeited | (1,217,189 | ) |  | $1.96 |  | (447,629 | ) |  | $6.18
Expired | (3,364,120 | ) |  | $1.82 |  | — |  |  | —
Outstanding at December 31, 2011 | 17,143,505 |  |  | $1.71 |  | 37,389,825 |  |  | $2.35
Changes during the Year: |  |  |  |  |  |  |
Granted | 7,787,529 |  |  | $0.50 |  | 31,082,615 |  |  | $0.57
Exercised | — |  |  | — |  | (11,076,182 | ) |  | $0.60
Forfeited | (3,020,209 | ) |  | $1.66 |  | (790,003 | ) |  | $2.17
Expired | (224,145 | ) |  | $1.88 |  | (1,318,644 | ) |  | $4.60
Outstanding at December 31, 2012 | 21,686,680 |  |  | $1.29 |  | 55,287,611 |  |  | $1.57
The following table summarizes the components of share-based compensation expense for the years ended December 31, 2012 and 2011 (in thousands):
| Year Ended December 31,
| 2012 |  | 2011
Cost of goods sold | $ | 195.0 |  |  | $ | 96.9 |
Research and development | 432.9 |  |  | 867.8 |
Selling, general and administrative | 6,084.6 |  |  | 9,301.3 |
Total share-based compensation expense | $ | 6,712.5 |  |  | $ | 10,266.0 |
Disclosure of Share-based Compensation Arrangements by Share-based Payment Award [Table Text Block] | Total compensation cost related to nonvested awards not yet recognized and the weighted-average periods over which the awards are expected to be recognized at December 31, 2012 were as follows (dollars in thousands):
| Stock Options |  | Warrants |  | Restricted Stock
Unrecognized compensation cost | $ | 1,620.1 |  |  | $ | 20.5 |  |  | $ | 143.0 |
Expected weighted-average period in years of compensation cost to be recognized | 1.68 |  |  | 0.44 |  |  | 0.19 |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value [Table Text Block] | Total fair value of shares vested and the weighted average estimated fair values of shares grant for the years ended December 31, 2012 and 2011 were as follows (dollars in thousands):
|  | Stock Options |  | Warrants
|  | Year Ended December 31, |  | Year Ended December 31,
|  | 2012 |  | 2011 |  | 2012 |  | 2011
Total fair value of shares vested |  | $ | 5,408.0 |  |  | $ | 6,194.1 |  |  | $ | 171.6 |  |  | $ | 269.1 |
Weighted average estimated fair value of shares granted |  | 0.36 |  |  | 1.06 |  |  | 0.41 |  |  | 0.74 |
Schedule of Range of Fair Value of Stock Options and Warrants [Table Text Block] | The range of assumptions made in calculating the fair values of stock options and warrants was as follow:
|  | Stock Options |  | Warrants
|  | Year Ended December 31, |  | Year Ended December 31,
|  | 2012 |  | 2011 |  | 2012 |  | 2011
Expected term - minimum (in years) |  | 2 |  | 3 |  | 2 |  | 3
Expected term - maximum (in years) |  | 10 |  | 10 |  | 5 |  | 5
Expected volatility - minimum |  | 73% |  | 79% |  | 76% |  | 80%
Expected volatility - maximum |  | 84% |  | 85% |  | 83% |  | 86%
Expected dividend yield |  | — |  | — |  | — |  | —
Risk-free interest rate - minimum |  | 0.28% |  | 0.40% |  | 0.27% |  | 0.78%
Risk-free interest rate - maximum |  | 1.99% |  | 3.45% |  | 0.88% |  | 2.19%

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- Definition Tabular disclosure of components of a stock option or other award plan under which equity-based compensation is awarded to employees, typically comprised of the amount of unearned compensation (deferred compensation cost), compensation expense, and changes in the quantity and fair value of the shares (or other type of equity) granted, exercised, forfeited, and issued and outstanding pertaining to that plan. Disclosure may also include nature and general terms of such arrangements that existed during the period and potential effects of those arrangements on shareholders, effect of compensation cost arising from equity-based payment arrangements on the income statement, method of estimating the fair value of the goods or services received, or the fair value of the equity instruments granted, during the period, cash flow effects resulting from equity-based payment arrangements and, for registrants that accelerate vesting of out of the money share options, reasons for the decision to accelerate. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Statement of Financial Accounting Standard (FAS) -Number 123R -Paragraph 64, 65, A240 -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5047-113901 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the number and weighted-average exercise prices (or conversion ratios) for share options (or share units) that were outstanding at the beginning and end of the year, vested and expected to vest, exercisable or convertible at the end of the year, and the number of share options or share units that were granted, exercised or converted, forfeited, and expired during the year. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Topic 718 -SubTopic 10 -Publisher FASB -Number -Article -Subparagraph (c)(1) -Name Accounting Standards Codification -Paragraph 2 -Section 50 -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the weighted-average grant-date fair value of equity options or other equity instruments granted during the year. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Topic 718 -SubTopic 10 -Publisher FASB -Number -Article -Subparagraph (d)(1) -Name Accounting Standards Codification -Paragraph 2 -Section 50 -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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