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Shareholders' Equity (Tables) | 12 Months Ended
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Dec. 31, 2012
Shareholders’ Equity [Abstract] |
Schedule of Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Table Text Block] | The number of remaining shares authorized to be issued under the various equity plans are as follows:
|  | 2003 Equity Plan |  | 2009 Equity Plan
Shares Authorized for Issuance |  | 2,500,000 |  |  | 33,950,000 |
Outstanding Stock Options |  | (1,390,300 | ) |  | (20,296,380 | )
Exercised Stock Options |  | (92,500 | ) |  | (5,000 | )
Restricted stock or equity grants issued under Equity Plans |  | (889,939 | ) |  | (4,606,482 | )
Total common shares remaining to be issued under the Equity Plans |  | 127,261 |  |  | 9,042,138 |
Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block] | The following table summarizes the activity for stock options and warrants for the year ended December 31, 2012:
| Stock Options |  | Warrants
| Shares |  | Weighted Average Exercise Price |  | Shares |  | Weighted Average Exercise Price
Outstanding at December 31, 2010 | 13,032,214 |  |  | $1.66 |  | 21,843,507 |  |  | $2.62
Changes during the Year: |  |  |  |  |  |  |
Granted | 8,697,600 |  |  | $1.50 |  | 15,993,947 |  |  | $2.09
Exercised | (5,000 | ) |  | $1.42 |  | — |  |  | —
Forfeited | (1,217,189 | ) |  | $1.96 |  | (447,629 | ) |  | $6.18
Expired | (3,364,120 | ) |  | $1.82 |  | — |  |  | —
Outstanding at December 31, 2011 | 17,143,505 |  |  | $1.71 |  | 37,389,825 |  |  | $2.35
Changes during the Year: |  |  |  |  |  |  |
Granted | 7,787,529 |  |  | $0.50 |  | 31,082,615 |  |  | $0.57
Exercised | — |  |  | — |  | (11,076,182 | ) |  | $0.60
Forfeited | (3,020,209 | ) |  | $1.66 |  | (790,003 | ) |  | $2.17
Expired | (224,145 | ) |  | $1.88 |  | (1,318,644 | ) |  | $4.60
Outstanding at December 31, 2012 | 21,686,680 |  |  | $1.29 |  | 55,287,611 |  |  | $1.57
The following table summarizes the components of share-based compensation expense for the years ended December 31, 2012 and 2011 (in thousands):
| Year Ended December 31,
| 2012 |  | 2011
Cost of goods sold | $ | 195.0 |  |  | $ | 96.9 |
Research and development | 432.9 |  |  | 867.8 |
Selling, general and administrative | 6,084.6 |  |  | 9,301.3 |
Total share-based compensation expense | $ | 6,712.5 |  |  | $ | 10,266.0 |
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block] | During the years ended December 31, 2012 and 2011, the Company issued warrants for services as follows ($ in thousands, except share data):
|  | Year Ended December 31,
|  | 2012 |  | 2011
Number of Common Stock Purchase Warrants Issued |  | 419,690 |  |  | 670,000 |
Value of Common Stock Purchase Warrants Issued |  | $ | 172.2 |  |  | $ | 495.1 |
Restricted Stock [Table Text Block] | During the years ended December 31, 2012 and 2011, the Company issued restricted stock for services as follows ($ in thousands, except share data):
|  | Year Ended December 31,
|  | 2012 |  | 2011
Number of Restricted Stock Issued |  | 2,295,533 |  |  | 3,467,451 |
Value of Restricted Stock Issued |  | $ | 1,325.1 |  |  | $ | 3,580.6 |

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- Definition Tabular disclosure of the amount of total share-based compensation cost, including the amounts attributable to each share-based compensation plan and any related tax benefits. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Topic 718 -SubTopic 10 -Publisher FASB -Number -Article -Subparagraph (h)(1) -Name Accounting Standards Codification -Paragraph 2 -Section 50 -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the number and weighted-average exercise prices (or conversion ratios) for share options (or share units) that were outstanding at the beginning and end of the year, vested and expected to vest, exercisable or convertible at the end of the year, and the number of share options or share units that were granted, exercised or converted, forfeited, and expired during the year. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Topic 718 -SubTopic 10 -Publisher FASB -Number -Article -Subparagraph (c)(1) -Name Accounting Standards Codification -Paragraph 2 -Section 50 -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of warrants or rights issued. Warrants and rights outstanding are derivative securities that give the holder the right to purchase securities (usually equity) from the issuer at a specific price within a certain time frame. Warrants are often included in a new debt issue to entice investors by a higher return potential. The main difference between warrants and call options is that warrants are issued and guaranteed by the company, whereas options are exchange instruments and are not issued by the company. Also, the lifetime of a warrant is often measured in years, while the lifetime of a typical option is measured in months. Disclose the title of issue of securities called for by warrants and rights outstanding, the aggregate amount of securities called for by warrants and rights outstanding, the date from which the warrants or rights are exercisable, and the price at which the warrant or right is exercisable. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 235 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.4-08.(i)) -URI http://asc.fasb.org/extlink&oid=6881521&loc=d3e23780-122690 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 50 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6406099&loc=d3e25284-112666 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Emerging Issues Task Force (EITF) -Number D-98 -Paragraph 2 -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5047-113901 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 02 -Paragraph 28 -Article 5 Reference 6: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Article 4 -Section 08 -Paragraph i Reference 7: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 50 -Section S99 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6784392&loc=d3e188667-122775 + Details
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