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Share-Based Compensation (Tables)
12 Months Ended
Dec. 31, 2012
Share-based Compensation [Abstract]  
Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block]
The following table summarizes the activity for stock options and warrants for the year ended December 31, 2012:
 
Stock Options
 
Warrants
 
Shares
 
Weighted Average Exercise Price
 
Shares
 
Weighted Average Exercise Price
Outstanding at December 31, 2010
13,032,214

 
$1.66
 
21,843,507

 
$2.62
 
 
 
 
 
 
 
 
Changes during the Year:
 
 
 
 
 
 
 
Granted
8,697,600

 
$1.50
 
15,993,947

 
$2.09
Exercised
(5,000
)
 
$1.42
 

 
Forfeited
(1,217,189
)
 
$1.96
 
(447,629
)
 
$6.18
Expired
(3,364,120
)
 
$1.82
 

 
Outstanding at December 31, 2011
17,143,505

 
$1.71
 
37,389,825

 
$2.35
 
 
 
 
 
 
 
 
Changes during the Year:
 
 
 
 
 
 
 
Granted
7,787,529

 
$0.50
 
31,082,615

 
$0.57
Exercised

 
 
(11,076,182
)
 
$0.60
Forfeited
(3,020,209
)
 
$1.66
 
(790,003
)
 
$2.17
Expired
(224,145
)
 
$1.88
 
(1,318,644
)
 
$4.60
Outstanding at December 31, 2012
21,686,680

 
$1.29
 
55,287,611

 
$1.57
 
 
 
 
 
 
 
 
The following table summarizes the components of share-based compensation expense for the years ended December 31, 2012 and 2011 (in thousands):
 
Year Ended December 31,
 
2012
 
2011
Cost of goods sold
$
195.0

 
$
96.9

Research and development
432.9

 
867.8

Selling, general and administrative
6,084.6

 
9,301.3

Total share-based compensation expense
$
6,712.5

 
$
10,266.0

 
 
 
 
Disclosure of Share-based Compensation Arrangements by Share-based Payment Award [Table Text Block]
Total compensation cost related to nonvested awards not yet recognized and the weighted-average periods over which the awards are expected to be recognized at December 31, 2012 were as follows (dollars in thousands):
 
Stock Options
 
Warrants
 
Restricted Stock
Unrecognized compensation cost
$
1,620.1

 
$
20.5

 
$
143.0

Expected weighted-average period in years of compensation cost to be recognized
1.68

 
0.44

 
0.19

Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value [Table Text Block]
Total fair value of shares vested and the weighted average estimated fair values of shares grant for the years ended December 31, 2012 and 2011 were as follows (dollars in thousands):
 
 
Stock Options
 
Warrants
 
 
Year Ended December 31,
 
Year Ended December 31,
 
 
2012
 
2011
 
2012
 
2011
Total fair value of shares vested
 
$
5,408.0

 
$
6,194.1

 
$
171.6

 
$
269.1

Weighted average estimated fair value of shares granted
 
0.36

 
1.06

 
0.41

 
0.74

Schedule of Range of Fair Value of Stock Options and Warrants [Table Text Block]
The range of assumptions made in calculating the fair values of stock options and warrants was as follow:
 
 
Stock Options
 
Warrants
 
 
Year Ended December 31,
 
Year Ended December 31,
 
 
2012
 
2011
 
2012
 
2011
Expected term - minimum (in years)
 
2
 
3
 
2
 
3
Expected term - maximum (in years)
 
10
 
10
 
5
 
5
Expected volatility - minimum
 
73%
 
79%
 
76%
 
80%
Expected volatility - maximum
 
84%
 
85%
 
83%
 
86%
Expected dividend yield
 
 
 
 
Risk-free interest rate - minimum
 
0.28%
 
0.40%
 
0.27%
 
0.78%
Risk-free interest rate - maximum
 
1.99%
 
3.45%
 
0.88%
 
2.19%