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Shareholders' Equity (Details) - USD ($) | 1 Months Ended | 12 Months Ended |  |  |  |  |  |
--- | --- | --- | --- | --- | --- | --- | --- | ---
Nov. 30, 2015 | Dec. 31, 2015 | Dec. 31, 2014 | Dec. 31, 2013 | Oct. 10, 2012 | Oct. 14, 2011 | Jan. 18, 2011 | Jun. 02, 2010 | Oct. 29, 2009 | May. 09, 2009
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Proceeds from issuance of common stock |  | $ 36,471,269 | $ 16,710,645 | $ 58,736,166 |  |  |  |  |  |
weighted average estimated fair value of restricted stock |  | $ 2.68 | $ 5.44 |  |  |  |  |  |  |
Stock Issued During Period, Shares, Restricted Stock Award, Gross |  | 928,000 | 917,907 |  |  |  |  |  |  |
Proceeds from Warrant Exercises |  | $ 0 | $ 1,720,725 | 3,028,241 |  |  |  |  |  |
Stock Issued During Period, Value, Warrant Inducements |  |  |  | 62,014 |  |  |  |  |  |
Stock Issued During Period, Value, Restricted Stock Award, Gross |  | 2,488,600 | 4,996,300 |  |  |  |  |  |  |
Common Stock [Member] |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Proceeds from issuance of common stock |  | $ 19,021 | $ 2,959 | $ 9,713 |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues |  | 19,021,155 | 2,959,214 | 9,712,724 |  |  |  |  |  |
Stock Issued During Period, Value, Warrant Inducements |  |  |  | $ 0 |  |  |  |  |  |
Warrant inducements |  |  |  | 0 |  |  |  |  |  |
Aspire Capital Purchase Agreement [Member] |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Proceeds from issuance of common stock |  | $ 300,000 |  |  |  |  |  |  |  |
Term Of Agreement In Months | 24 months |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, Other | 842,696 | 200,000 |  |  |  |  |  |  |  |
Discount Applied To Weighted Average Price | 5.00% |  |  |  |  |  |  |  |  |
Common Stock [Member] |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Common stock, shares authorized (shares) |  | 500,000,000 | 500,000,000 |  |  |  |  |  |  |
Non US Equity Plan [Member] | Stock Options [Member] |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Common stock, shares authorized (shares) |  |  |  |  | 570,000 |  |  |  |  |
2009 Equity Plan [Member] | Stock Options [Member] |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Common stock, shares authorized (shares) |  | 8,995,000 | 5,995,000 |  | 450,000 | 2,375,000 | 1,775,000 | 1,375,000 | 975,000 | 380,000
US Equity Plan [Member] | 2015 Equity Plan [Member] [Member] | Stock Options [Member] | 2015 Equity Plan [Member] [Member] |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Common stock, shares authorized (shares) |  | 4,400,000 |  |  |  |  |  |  |  |
Initial Reserve Or Shares, Percent Increase Each Year |  | 4.00% |  |  |  |  |  |  |  |
Initial Reserve, Increase In Number Of Shares Each Year |  | 176,000 |  |  |  |  |  |  |  |
US Equity Plan [Member] | 2009 Equity Plan [Member] | Stock Options [Member] | 2009 Equity Plan [Member] |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Common stock, shares authorized (shares) |  | 8,995,000 |  |  |  |  |  |  |  |

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