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Shareholders' Equity (Details) - USD ($)
 1 Months Ended 12 Months Ended
Nov. 30, 2015
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Oct. 10, 2012
Oct. 14, 2011
Jan. 18, 2011
Jun. 02, 2010
Oct. 29, 2009
May. 09, 2009
Class of Stock [Line Items]                    
Proceeds from issuance of common stock   $ 36,471,269 $ 16,710,645 $ 58,736,166            
weighted average estimated fair value of restricted stock   $ 2.68 $ 5.44              
Stock Issued During Period, Shares, Restricted Stock Award, Gross   928,000 917,907              
Proceeds from Warrant Exercises   $ 0 $ 1,720,725 3,028,241            
Stock Issued During Period, Value, Warrant Inducements       62,014            
Stock Issued During Period, Value, Restricted Stock Award, Gross   2,488,600 4,996,300              
Common Stock [Member]                    
Class of Stock [Line Items]                    
Proceeds from issuance of common stock   $ 19,021 $ 2,959 $ 9,713            
Stock Issued During Period, Shares, New Issues   19,021,155 2,959,214 9,712,724            
Stock Issued During Period, Value, Warrant Inducements       $ 0            
Warrant inducements       0            
Aspire Capital Purchase Agreement [Member]                    
Class of Stock [Line Items]                    
Proceeds from issuance of common stock   $ 300,000                
Term Of Agreement In Months 24 months                  
Stock Issued During Period, Shares, Other 842,696 200,000                
Discount Applied To Weighted Average Price 5.00%                  
Common Stock [Member]                    
Class of Stock [Line Items]                    
Common stock, shares authorized (shares)   500,000,000 500,000,000              
Non US Equity Plan [Member] | Stock Options [Member]                    
Class of Stock [Line Items]                    
Common stock, shares authorized (shares)         570,000          
2009 Equity Plan [Member] | Stock Options [Member]                    
Class of Stock [Line Items]                    
Common stock, shares authorized (shares)   8,995,000 5,995,000   450,000 2,375,000 1,775,000 1,375,000 975,000 380,000
US Equity Plan [Member] | 2015 Equity Plan [Member] [Member] | Stock Options [Member] | 2015 Equity Plan [Member] [Member]                    
Class of Stock [Line Items]                    
Common stock, shares authorized (shares)   4,400,000                
Initial Reserve Or Shares, Percent Increase Each Year   4.00%                
Initial Reserve, Increase In Number Of Shares Each Year   176,000                
US Equity Plan [Member] | 2009 Equity Plan [Member] | Stock Options [Member] | 2009 Equity Plan [Member]                    
Class of Stock [Line Items]                    
Common stock, shares authorized (shares)   8,995,000