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Shareholders' Equity - Stock options and warrants (Details) | 6 Months Ended | 12 Months Ended |
--- | --- | --- | ---
Jun. 30, 2016 USD ($) $ / shares $ / warrant shares | Dec. 31, 2015 USD ($) $ / shares $ / warrant shares | Mar. 10, 2016 shares
Stock Options and Warrants [Line Items] |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value | $ | $ 18,900 | $ 100 |
Common Stock Warrants, Shares | 460,049 | 321,404 | 141,844
Weighted Average Exercise Price, Warrants Outstanding | $ / warrant | 98.00 | 137.20 |
Weighted Average Remaining Contractual Term warrant outstanding | 1 year 22 days | 1 year 3 months 4 days |
Aggregate Intrinsic Value, Warrants Outstanding | $ | $ 0 | $ 0 |
Warrants Granted | 141,845 |  |
Warrants Canceled | (3,200.0) |  |
Weighted Average Exercise Price, Warrants Granted | $ / shares | $ 122.60 |  |
Warrants Exercised | 0 |  |
Weighted Average Exercise Price, Warrants Exercised | $ / shares | $ 0.00 |  |
Warrants Expired | 0 |  |
Weighted Average Exercise Price, Warrants Expired | $ / shares | $ 0.00 |  |
Weighted Average Exercise Price, Warrants Canceled | $ / shares | $ 147.50 |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value | $ | $ 18,400 |  |
shares, vested and expected to vest | 460,049 |  |
Weighted Average Exercise Price, Warrants vested & expected to vest | $ / warrant | 98.00 |  |
Aggregate Intrinsic Value, Warrants vested and expected to vest | $ | $ 0 |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value | $ | $ 9,000 |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number | 460,300 |  |
Weighted Average Exercise Price, Warrants Exercisable | $ / warrant | 98.00 |  |
weighted Average Remaining Contractual Term, warrants vested | 1 year 22 days |  |
Aggregate Intrinsic Value, Warrants vested | $ | $ 0 |  |
US Equity Plan [Member] |  |  |
Stock Options and Warrants [Line Items] |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number | 692,332 | 666,348.0 |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price | $ / shares | $ 55.00 | $ 64.60 |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term | 7 years 4 months 2 days | 6 years 10 months 17 days |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Net of Forfeitures | 169,038 |  |
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price | $ / shares | $ 6.20 |  |
Stock Options Exercised | 0 |  |
Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price | $ / shares | $ 0.00 |  |
Stock Options Expired | (56,024) |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price | $ / shares | $ 35.90 |  |
Stock Options Forfeited | (87,030) |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price | $ / shares | $ 46.50 |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number | 675,324 |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price | $ / shares | $ 56.00 |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term | 7 years 3 months 15 days |  |
Weighted Average Remaining Contractual Term, Warrants Vested and Expect to Vest | 1 year 22 days |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number | 489,652 |  |
Weighted average estimated fair value of shares granted | $ / shares | $ 71.00 |  |
Options, Vested, weighted Average Remaining Contractual Term | 6 years 6 months 18 days |  |

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