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Shareholders' Equity (Details) |  |  | 1 Months Ended | 12 Months Ended |  |  |  |  |  |  |  |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Jul. 28, 2016 | Mar. 10, 2016 USD ($) $ / shares shares | Nov. 30, 2015 | Dec. 31, 2016 USD ($) $ / shares shares | Dec. 31, 2015 USD ($) $ / shares shares | Dec. 31, 2014 shares | Oct. 06, 2014 shares | Oct. 03, 2013 shares | Oct. 10, 2012 shares | Oct. 14, 2011 shares | Jan. 18, 2011 shares | Jun. 02, 2010 shares | Oct. 29, 2009 shares | May 09, 2009 shares
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock Split, Conversion Ratio | 0.1 |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock, shares, issued (shares) |  | 141,844 |  |  |  |  |  |  |  |  |  |  |  |
Common Stock Warrants, Shares |  | 141,844 |  |  | 321,404 |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares |  | $ 10.00 |  |  |  |  |  |  |  |  |  |  |  |
Share Price | $ / shares |  | $ 7.05 |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from Issuance of Warrants | $ |  | $ 1,000,000 |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from issuance of common stock | $ |  |  |  | $ 11,560,394 | $ 36,471,269 |  |  |  |  |  |  |  |  |
weighted average estimated fair value of restricted stock | $ / shares |  |  |  | $ 5.50 | $ 26.82 |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, Restricted Stock Award, Gross |  |  |  | 126,849 | 92,800 |  |  |  |  |  |  |  |  |
Stock Issued During Period, Value, Restricted Stock Award, Gross | $ |  |  |  | $ 698,100 | $ 2,488,600 |  |  |  |  |  |  |  |  |
Common Stock [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares, Outstanding |  |  |  | 8,205,790 | 5,673,302 | 3,678,386 |  |  |  |  |  |  |  |
Proceeds from issuance of common stock | $ |  |  |  | $ 2,419 | $ 1,902 |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues |  |  |  | 2,418,144 | 1,902,116 |  |  |  |  |  |  |  |  |
Aspire Capital Purchase Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares, Issued |  |  |  | 109,270 |  |  |  |  |  |  |  |  |  |
Term Of Agreement In Months |  |  | 24 months |  |  |  |  |  |  |  |  |  |  |
Discount Applied To Weighted Average Price |  |  | 5.00% |  |  |  |  |  |  |  |  |  |  |
Common Stock [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock, par value (USD per share) | $ / shares |  |  |  | $ 0.001 | $ 0.001 |  |  |  |  |  |  |  |  |
Common stock, shares, issued (shares) |  |  |  | 8,205,790 | 5,673,301.2 |  |  |  |  |  |  |  |  |
Common stock, shares authorized (shares) |  |  |  | 500,000,000 | 500,000,000 |  |  |  |  |  |  |  |  |
ESPP [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares, Issued |  |  |  | 25,535 |  |  |  |  |  |  |  |  |  |
Shares, Outstanding |  |  |  | 4,454 |  |  |  |  |  |  |  |  |  |
Common stock, shares authorized (shares) |  |  |  | 50,000 |  |  |  |  |  |  |  |  |  |
Non US Equity Plan [Member] | Stock Options [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock, shares authorized (shares) |  |  |  |  |  |  |  |  | 57,000 |  |  |  |  |
2009 Equity Plan [Member] | Stock Options [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock, shares authorized (shares) |  |  |  |  |  |  | 899,500 | 599,500 | 45,000 | 237,500 | 177,500 | 137,500 | 97,500 | 38,000
US Equity Plan [Member] | 2015 Equity Plan [Member] | Stock Options [Member] | 2015 Equity Plan [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock, shares authorized (shares) |  |  |  | 440,000 |  |  |  |  |  |  |  |  |  |
Common Stock, Shares Authorized, Period for Automatic Increase |  |  |  | 10 years |  |  |  |  |  |  |  |  |  |
Initial Reserve Or Shares, Percent Increase Each Year |  |  |  | 4.00% |  |  |  |  |  |  |  |  |  |
Initial Reserve, Increase In Number Of Shares Each Year |  |  |  | 17,600 |  |  |  |  |  |  |  |  |  |
US Equity Plan [Member] | 2009 Equity Plan [Member] | Stock Options [Member] | 2009 Equity Plan [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock, shares authorized (shares) |  |  |  | 899,500 |  |  |  |  |  |  |  |  |  |

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