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Shareholders' Equity (Details)
 1 Months Ended 12 Months Ended
Jul. 28, 2016
Mar. 10, 2016
USD ($)
$ / shares
shares
Nov. 30, 2015
Dec. 31, 2016
USD ($)
$ / shares
shares
Dec. 31, 2015
USD ($)
$ / shares
shares
Dec. 31, 2014
shares
Oct. 06, 2014
shares
Oct. 03, 2013
shares
Oct. 10, 2012
shares
Oct. 14, 2011
shares
Jan. 18, 2011
shares
Jun. 02, 2010
shares
Oct. 29, 2009
shares
May 09, 2009
shares
Class of Stock [Line Items]                            
Stock Split, Conversion Ratio 0.1                          
Common stock, shares, issued (shares)   141,844                        
Common Stock Warrants, Shares   141,844     321,404                  
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares   $ 10.00                        
Share Price | $ / shares   $ 7.05                        
Proceeds from Issuance of Warrants | $   $ 1,000,000                        
Proceeds from issuance of common stock | $       $ 11,560,394 $ 36,471,269                  
weighted average estimated fair value of restricted stock | $ / shares       $ 5.50 $ 26.82                  
Stock Issued During Period, Shares, Restricted Stock Award, Gross       126,849 92,800                  
Stock Issued During Period, Value, Restricted Stock Award, Gross | $       $ 698,100 $ 2,488,600                  
Common Stock [Member]                            
Class of Stock [Line Items]                            
Shares, Outstanding       8,205,790 5,673,302 3,678,386                
Proceeds from issuance of common stock | $       $ 2,419 $ 1,902                  
Stock Issued During Period, Shares, New Issues       2,418,144 1,902,116                  
Aspire Capital Purchase Agreement [Member]                            
Class of Stock [Line Items]                            
Shares, Issued       109,270                    
Term Of Agreement In Months     24 months                      
Discount Applied To Weighted Average Price     5.00%                      
Common Stock [Member]                            
Class of Stock [Line Items]                            
Common stock, par value (USD per share) | $ / shares       $ 0.001 $ 0.001                  
Common stock, shares, issued (shares)       8,205,790 5,673,301.2                  
Common stock, shares authorized (shares)       500,000,000 500,000,000                  
ESPP [Member]                            
Class of Stock [Line Items]                            
Shares, Issued       25,535                    
Shares, Outstanding       4,454                    
Common stock, shares authorized (shares)       50,000                    
Non US Equity Plan [Member] | Stock Options [Member]                            
Class of Stock [Line Items]                            
Common stock, shares authorized (shares)                 57,000          
2009 Equity Plan [Member] | Stock Options [Member]                            
Class of Stock [Line Items]                            
Common stock, shares authorized (shares)             899,500 599,500 45,000 237,500 177,500 137,500 97,500 38,000
US Equity Plan [Member] | 2015 Equity Plan [Member] | Stock Options [Member] | 2015 Equity Plan [Member]                            
Class of Stock [Line Items]                            
Common stock, shares authorized (shares)       440,000                    
Common Stock, Shares Authorized, Period for Automatic Increase       10 years                    
Initial Reserve Or Shares, Percent Increase Each Year       4.00%                    
Initial Reserve, Increase In Number Of Shares Each Year       17,600                    
US Equity Plan [Member] | 2009 Equity Plan [Member] | Stock Options [Member] | 2009 Equity Plan [Member]                            
Class of Stock [Line Items]                            
Common stock, shares authorized (shares)       899,500