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Shareholders' Equity - Equity Issuances (Details)
 1 Months Ended 3 Months Ended
Mar. 22, 2017
USD ($)
shares
Sep. 14, 2016
USD ($)
clinical_trial_subject
$ / shares
shares
Nov. 30, 2015
USD ($)
shares
Mar. 31, 2017
USD ($)
shares
Mar. 31, 2016
USD ($)
Dec. 31, 2016
shares
May 01, 2015
USD ($)
Class of Stock [Line Items]              
Common Stock Warrants, Shares | shares       336,062   388,062  
Shares Issued, Price Per Share | $ / shares   $ 4.72          
Net proceeds from issuance of common stock       $ 3,241,460 $ 1,096,208    
Common Stock, Shares, Issued | shares       8,953,312   8,205,791  
RD Purchase Agreement [Member]              
Class of Stock [Line Items]              
Stock Issued During Period, Shares, New Issues | shares 423,729 847,458          
Proceeds from Issuance of Common Stock $ 2,000,000 $ 4,000,000          
Private Purchase Agreement [Member]              
Class of Stock [Line Items]              
Proceeds from Issuance of Common Stock       $ 6,000,000      
Proceeds from Issuance of Common Stock, Second Closing, Receivable       4,000,000      
Purchase Commitment, Maximum Amount Committed, Shares | shares   4,449,153          
Proceeds from Issuance of Common Stock, Initial Closing   $ 12,600,000          
Proceeds from Issuance of Common Stock, Second Closing   $ 8,400,000          
Number of Subjects, Phase 2 CLBS03 Clinical Trial, Second Closing | clinical_trial_subject   70          
Aspire Capital Purchase Agreement [Member]              
Class of Stock [Line Items]              
Proceeds from Issuance of Common Stock       $ 1,200,000      
Purchase Commitment, Maximum Amount Committed, Shares | shares     1,101,927.6        
Purchase Commitment, Remaining Minimum Amount Committed     $ 30,000,000        
Term of agreement in months     24 months        
Stock Issued During Period, Shares, Other | shares     84,269.6 210,506      
Shares, Issued | shares       319,776      
Common Stock, Value, Issued       $ 1,500,000      
Discount Applied To Weighted Average Price     5.00%        
Aspire Capital Purchase Agreement [Member]              
Class of Stock [Line Items]              
Purchase Commitment, Remaining Minimum Amount Committed             $ 30,000,000
Common Stock, Shares, Issued | shares       36,483.7