<SEC-DOCUMENT>0001144204-17-006290.txt : 20170206
<SEC-HEADER>0001144204-17-006290.hdr.sgml : 20170206
<ACCEPTANCE-DATETIME>20170206194703
ACCESSION NUMBER:		0001144204-17-006290
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20170202
FILED AS OF DATE:		20170206
DATE AS OF CHANGE:		20170206

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Caladrius Biosciences, Inc.
		CENTRAL INDEX KEY:			0000320017
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-MISC HEALTH & ALLIED SERVICES, NEC [8090]
		IRS NUMBER:				222343568
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		106 ALLEN ROAD
		STREET 2:		FOURTH FLOOR
		CITY:			BASKING RIDGE
		STATE:			NJ
		ZIP:			07920
		BUSINESS PHONE:		908-842-0100

	MAIL ADDRESS:	
		STREET 1:		106 ALLEN ROAD
		STREET 2:		FOURTH FLOOR
		CITY:			BASKING RIDGE
		STATE:			NJ
		ZIP:			07920

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	NeoStem, Inc.
		DATE OF NAME CHANGE:	20060906

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PHASE III MEDICAL INC/DE
		DATE OF NAME CHANGE:	20030819

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CORNICHE GROUP INC /DE
		DATE OF NAME CHANGE:	19951117

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Wei Eric
		CENTRAL INDEX KEY:			0001368570

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33650
		FILM NUMBER:		17576939

	MAIL ADDRESS:	
		STREET 1:		SUITE 602, CHINA LIFE TOWER
		STREET 2:		16 CHAOWAI DISTRICT
		CITY:			BEIJING
		STATE:			F4
		ZIP:			100020
</SEC-HEADER>
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<TYPE>4
<SEQUENCE>1
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<DESCRIPTION>OWNERSHIP DOCUMENT
<TEXT>
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    <periodOfReport>2017-02-02</periodOfReport>

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    <issuer>
        <issuerCik>0000320017</issuerCik>
        <issuerName>Caladrius Biosciences, Inc.</issuerName>
        <issuerTradingSymbol>CLBS</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001368570</rptOwnerCik>
            <rptOwnerName>Wei Eric</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O CALADRIUS BIOSCIENCES, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>106 ALLEN ROAD</rptOwnerStreet2>
            <rptOwnerCity>BASKING RIDGE</rptOwnerCity>
            <rptOwnerState>NJ</rptOwnerState>
            <rptOwnerZipCode>07920</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle></officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
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            <transactionDate>
                <value>2017-02-02</value>
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                <equitySwapInvolved>0</equitySwapInvolved>
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                <transactionPricePerShare>
                    <value>4.5094</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
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                    <value>4.7507</value>
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            <transactionDate>
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                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
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                <transactionShares>
                    <value>1525</value>
                    <footnoteId id="F1"/>
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                <transactionPricePerShare>
                    <value>4.7582</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
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                <sharesOwnedFollowingTransaction>
                    <value>179298</value>
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                    <value>I</value>
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            <securityTitle>
                <value>Common Stock</value>
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            <transactionDate>
                <value>2017-02-06</value>
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                <transactionFormType>4</transactionFormType>
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                <transactionShares>
                    <value>500</value>
                    <footnoteId id="F1"/>
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                    <value>4.7500</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
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                    <value>178798</value>
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                    <value>I</value>
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                    <footnoteId id="F3"/>
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        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
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                <sharesOwnedFollowingTransaction>
                    <value>4300</value>
                    <footnoteId id="F4"/>
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                <directOrIndirectOwnership>
                    <value>D</value>
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    <footnotes>
        <footnote id="F1">The transactions reported in this line item were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person as of June 3, 2016.</footnote>
        <footnote id="F2">Following the reported transactions, 177,598 shares of Common Stock of the Issuer are held by RimAsia Capital Partners L.P., a Cayman Islands exempted limited partnership (&quot;RimAsia LP&quot;), and 1,200 shares of Common Stock of the Issuer are held by RimAsia Capital Partners Manager, Ltd., a Cayman Islands exempted company (&quot;RimAsia Manager&quot;).</footnote>
        <footnote id="F3">RimAsia Capital Partners GP, L.P., a Cayman Islands exempted limited partnership (&quot;RimAsia GP&quot;), is the general partner of RimAsia LP. RimAsia Manager is the Fund Manager of RimAsia GP and the Manager of RimAsia LP. Mr. Wei is the managing partner of RimAsia LP, an indirect partner of RimAsia GP, a director of RimAsia Capital Partners GP, Ltd. and a director of RimAsia Manager. As a result, Mr. Wei may be deemed to have sole power to vote certain of the securities held by RimAsia LP and RimAsia Manager. Mr. Wei disclaims beneficial ownership of such securities, except to the extent of his pecuniary interest therein, and the inclusion of these securities shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 of the Securities Exchange Act or for any other purpose.</footnote>
        <footnote id="F4">Includes 2,775 shares of unvested restricted stock granted under the Issuer's compensation plans.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>Eric H.C. Wei, By: /s/ Todd C. Girolamo, Esq., Attorney-in-Fact</signatureName>
        <signatureDate>2017-02-06</signatureDate>
    </ownerSignature>
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</SEC-DOCUMENT>
