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Stockholders' Equity - Equity Issuances (Details)
 1 Months Ended 12 Months Ended
Sep. 14, 2016
USD ($)
clinical_trial_subject
$ / shares
shares
Mar. 10, 2016
USD ($)
$ / shares
shares
Nov. 30, 2015
USD ($)
shares
Dec. 31, 2017
USD ($)
shares
Dec. 31, 2016
shares
Class of Stock [Line Items]          
Common stock, shares, issued (shares) | shares   141,844   9,483,911 8,205,790
Common Stock Warrants, Shares | shares   141,844     388,062
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares   $ 10.00      
Share Price | $ / shares   $ 7.05      
Proceeds from Issuance of Warrants   $ 1,000,000      
RD Purchase Agreement [Member]          
Class of Stock [Line Items]          
Stock Issued During Period, Shares, New Issues | shares 847,458        
Shares Issued, Price Per Share | $ / shares $ 4.72        
Proceeds from Issuance of Common Stock $ 4,000,000        
Private Purchase Agreement [Member]          
Class of Stock [Line Items]          
Stock Issued During Period, Shares, New Issues | shares       932,204  
Purchase Commitment, Maximum Amount Committed, Shares | shares 4,449,153        
Proceeds from Issuance of Common Stock, Initial Closing $ 12,600,000        
Proceeds from Issuance of Common Stock, Second Closing $ 8,400,000     $ 4,400,000  
Number of Subjects, Phase 2 CLBS03 Clinical Trial, Second Closing | clinical_trial_subject 70        
Proceeds from Issuance of Common Stock, Initial Closing, Receivable       6,000,000  
Proceeds from Issuance of Common Stock, Second Closing, Receivable       $ 4,000,000  
Aspire Capital Purchase Agreement [Member]          
Class of Stock [Line Items]          
Purchase Commitment, Maximum Amount Committed, Shares | shares     1,101,928    
Purchase Commitment, Remaining Minimum Amount Committed     $ 30,000,000    
Term Of Agreement In Months     24 months    
Shares, Issued | shares       319,776  
Financial Instruments Subject to Mandatory Redemption, Settlement Terms, Fair Value of Shares       $ 1,500,000