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The Business - Narrative (Details) $ in Millions | 1 Months Ended | 3 Months Ended |
--- | --- | --- | ---
Mar. 31, 2018 USD ($) | Jan. 31, 2018 patient | Dec. 31, 2017 USD ($) | Oct. 31, 2017 USD ($) | Oct. 31, 2016 patient | Mar. 31, 2018 USD ($) | Mar. 31, 2016 cohort | Feb. 28, 2017 USD ($)
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |
Revenue from grants | $ 0.3 |  | $ 1.9 | $ 1.9 |  | $ 7.9 |  |
Number of patients enrolled | patient |  | 110 |  |  | 19 |  |  |
Interim efficacy analysis, threshold (percent) |  |  |  |  | 50.00% |  |  |
Interim efficacy analysis, follow-up milestone period |  |  |  |  | 6 months |  |  |
Grants receivable | $ 8.6 |  |  |  |  | $ 8.6 |  | $ 12.2
The Sanford Project: T-Rex Study [Member] |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |
Number of cohorts | cohort |  |  |  |  |  |  | 2 |

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