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Shareholders' Equity - Equity Issuances (Details) |  | 1 Months Ended | 12 Months Ended |
--- | --- | --- | --- | ---
Sep. 14, 2016 USD ($) clinical_trial_subject $ / shares | Feb. 28, 2018 USD ($) | Nov. 30, 2015 USD ($) shares | Dec. 31, 2017 USD ($) shares | Dec. 31, 2016 shares | Mar. 31, 2018 USD ($) shares
Class of Stock [Line Items] |  |  |  |  |  |
Shares issued, price (in usd per share) | $ / shares | $ 4.72 |  |  |  |  |
Private Purchase Agreement [Member] |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |
Proceeds from issuance of common stock, initial closing | $ 6,600,000 |  |  |  |  |
Proceeds from issuance of common stock, second closing |  |  |  | $ 4,400,000 |  |
Stock issued (shares) | shares |  |  |  | 900,000 | 1,400,000 |
Number of subjects for Phase 2 CLBS03 clinical trial, second closing | clinical_trial_subject | 70 |  |  |  |  |
Aspire Capital Purchase Agreement [Member] |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |
Purchase commitment, remaining minimum amount committed |  |  | $ 30,000,000 |  |  |
Purchase commitment, maximum amount committed (shares) | shares |  |  | 1,100,000 |  |  |
Term of agreement in months |  |  | 24 months |  |  |
Shares, issued | shares |  |  |  |  |  | 319,776
Common stock issued, value |  |  |  |  |  | $ 1,500,000
H.C. Wainwright Sales Agreement [Member] |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |
Aggregate offering amount authorized per agreement |  | $ 12,000,000 |  |  |  |
Commission on gross proceeds due to third party (percent) |  | 3.00% |  |  |  |
Legal fees reimbursed to third party |  | $ 50,000 |  |  |  |
Quarterly filing fees payable, maximum |  | $ 2,500 |  |  |  |

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