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Consolidated Statements of Cash Flows - USD ($)
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Cash flows from operating activities:    
Net loss $ (4,984,441) $ (9,793,324)
Loss from discontinued operations 0 3,157,475
Adjustments to reconcile net loss to net cash used in operating activities:    
Share-based compensation 146,533 395,698
Depreciation and amortization 87,324 98,924
Loss on disposal of assets 0 47,301
Accretion on marketable securities 82,221 0
Changes in operating assets and liabilities:    
Prepaid and other current assets (2,447) 86,263
Accounts receivable 90,204 10,510
Other assets 0 20,141
Due to/from PCT 0 1,943,774
Accounts payable, accrued liabilities and other liabilities (1,717,871) (560,032)
Net cash used in operating activities - continuing operations (6,298,477) (4,593,270)
Net cash used in operating activities 0 (5,494,638)
Net cash used in operating activities (6,298,477) (10,087,908)
Cash flows from investing activities:    
Purchase of marketable securities (24,143,913) 0
Sale of marketable securities 22,964,000 0
Acquisition of property and equipment (8,528) (69,650)
Net cash used in investing activities - continuing operations (1,188,441) (69,650)
Net cash used in investing activities - discontinued operations 0 (101,626)
Net cash used in investing activities (1,188,441) (171,276)
Cash flows from financing activities:    
Proceeds from exercise of options 39,659 0
Tax withholding payments on net share settlement equity awards (45,169) (23,647)
Net proceeds from issuance of common stock 0 3,241,460
Repayment of long-term debt 0 (756,966)
Proceeds from notes payable 0 400,998
Repayment of notes payable (67,131) (193,518)
Advance payment received from potential PCT sale 0 5,000,000
Net cash (used in) provided by financing activities - continuing operations (72,641) 7,668,327
Net cash used in financing activities - discontinued operations 0 (116,545)
Net cash (used in) provided by financing activities (72,641) 7,551,782
Net decrease in cash, cash equivalents and restricted cash (7,559,559) (2,707,402)
Cash, cash equivalents and restricted cash at beginning of period - continuing operations 34,167,989 7,076,651
Cash and cash equivalents at beginning of period - discontinued operations 0 7,628,357
Cash, cash equivalents and restricted cash at end of period 26,608,430 11,997,606
Less cash and cash equivalents of discontinued operations at end of period 0 3,082,099
Cash, cash equivalents and restricted cash of continuing operations at end of period 26,608,430 8,915,507
Cash paid during the period for:    
Interest 3,295 130,204
Taxes $ 0 $ 0