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Share-Based Compensation (Details) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Jun. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share-based compensation expense $ 167,000 $ 62,000   $ 2,282,000 $ 2,771,000
Accelerated equity compensation cost     $ 1,900,000    
Modification incremental compensation cost     $ 300,000    
Stock Option [Member]          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Unrecognized compensation cost $ 685,000     $ 685,000  
Expected weighted-average period in years of compensation cost to be recognized       2 years 6 months 26 days  
Total fair value of shares vested       $ 218,000 $ 5,002,000
Weighted average estimated fair value of shares granted $ 2.61 $ 1.72   $ 2.61 $ 1.72
Restricted Stock [Member]          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Unrecognized compensation cost $ 0     $ 0  
Expected weighted-average period in years of compensation cost to be recognized       0 years  
Research and Development [Member]          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share-based compensation expense 32,000 $ 0   $ 413,000 $ 208,000
General and Administrative [Member]          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share-based compensation expense 135,000 62,000   1,869,000 1,674,000
Discontinued Operations [Member]          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share-based compensation expense $ 0 $ 0   $ 0 $ 889,000