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Consolidated Statements of Cash Flows - USD ($)
 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Cash flows from operating activities:    
Net (loss) income $ (12,610,857) $ 25,123,901
Income from discontinued operations 0 (37,329,963)
Adjustments to reconcile net (loss) income to net cash used in operating activities:    
Share-based compensation 2,281,077 1,881,712
Depreciation and amortization 207,981 284,005
(Gain) loss on disposal of assets (1,428,762) 175,793
Accretion on marketable securities 197,485 218,755
Changes in operating assets and liabilities:    
Prepaid and other current assets 209,522 717,711
Other assets 182,218 164,788
Due to/from PCT 0 (1,681,593)
Accounts payable, accrued liabilities and other liabilities (5,982,395) (5,823,272)
Net cash used in operating activities - continuing operations (16,943,731) (16,268,163)
Net cash used in operating activities - discontinued operations 0 (638,069)
Net cash used in operating activities (16,943,731) (16,906,232)
Cash flows from investing activities:    
Purchase of marketable securities (60,190,972) (51,724,691)
Sale of marketable securities 54,134,000 7,105,603
Proceeds from CFC device sale 2,550,000 0
Net proceeds from PCT sale 0 74,689,814
Net cash sold in PCT sale 0 (6,727,263)
Acquisition of property and equipment (133,679) (118,478)
Net cash (used in) provided by investing activities - continuing operations (3,640,651) 23,224,985
Net cash used in investing activities - discontinued operations 0 (188,794)
Net cash (used in) provided by investing activities (3,640,651) 23,036,191
Cash flows from financing activities:    
Proceeds from exercise of options 354,740 13,576
Tax withholding payments on net share settlement equity awards (402,532) (357,665)
Net proceeds from issuance of common stock 997,709 5,678,632
Repayment of long-term debt 0 (5,651,354)
Proceeds from notes payable 0 400,998
Repayment of notes payable (159,180) (764,402)
Net cash provided by (used in) financing activities - continuing operations 790,737 (680,215)
Net cash used in financing activities - discontinued operations 0 (74,231)
Net cash provided by (used in) financing activities 790,737 (754,446)
Net (decrease) increase in cash, cash equivalents and restricted cash (19,793,645) 5,375,513
Cash, cash equivalents and restricted cash at beginning of period - continuing operations 34,167,989 7,076,651
Cash and cash equivalents at beginning of period - discontinued operations 0 7,628,357
Cash, cash equivalents and restricted cash at end of period 14,374,344 20,080,521
Cash paid during the period for:    
Interest 5,148 706,231
Taxes $ 0 $ 0