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Income Taxes - Components of Deferred Income Taxes (Details) - USD ($) $ in Thousands | Dec. 31, 2018 | Dec. 31, 2017
--- | --- | ---
Components of Deferred Tax Assets and Liabilities [Abstract] |  |
Accumulated net operating losses (tax effected) | $ 60,544 | $ 60,171
CIRM funding | 1,033 | 1,780
Deferred rent | 5 | 3
Share-based compensation | 6,390 | 2,656
Intangibles | 199 | 270
Charitable contributions | 9 | 11
Accumulated depreciation | 9 | 22
Accrued payroll | 117 | 682
AMT credit | 0 | 575
Other | 525 | 526
Deferred tax assets | 68,831 | 66,696
Deferred tax liabilities | 0 | 0
Net deferred tax asset, before valuation allowance | 68,831 | 66,696
Valuation allowance | (68,831) | (66,121)
Net deferred tax asset | $ 0 | $ 575

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